I've been to Rome a number of times, and have tried a number of hotels, all with pros and cons. Artemide may well have the most pros-very conveniently located near Termini metro and railway stations and an easy walk to most major areas in the city center. Big enough to have a good restaurant, breakfast room, and spa/gym, but small enough to retain a bit of a boutique hotel feel. My room was well sound proofed and surprisingly quiet despite overlooking a major street. Room rate was very reasonable for a good hotel in the city center. If there was one big negative for me, it is that it is a bit of a hike to Trastevere and its restaurants.