
Popular airlines from Tocumen Intl. Airport (PTY) to San Francisco Intl. Airport (SFO)
- American Airlines
American Airlines
- Copa
Copa
- United
United
- Plan, book, fly with confidence
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Cheap flights from Panama City to San Francisco (PTY-SFO)
Prices were available within the past 7 days and start at €353 for one-way flights and €538 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, 5 Sep - Fri, 12 Sep
PTY
Panama City
SFO
San Francisco
€538 Return, found 1 day ago
€538
Return
found 1 day ago

Fri, 5 Sep - Fri, 12 Sep
PTY
Panama City
SFO
San Francisco
€563 Return, found 1 day ago
€563
Return
found 1 day ago

Fri, 5 Sep - Fri, 12 Sep
PTY
Panama City
SFO
San Francisco
€568 Return, found 1 day ago
€568
Return
found 1 day ago

Fri, 5 Sep - Fri, 12 Sep
PTY
Panama City
SFO
San Francisco
€581 Return, found 1 day ago
€581
Return
found 1 day ago

Fri, 5 Sep - Fri, 12 Sep
PTY
Panama City
SFO
San Francisco
€586 Return, found 1 day ago
€586
Return
found 1 day ago

Fri, 5 Sep - Fri, 12 Sep
PTY
Panama City
SFO
San Francisco
€591 Return, found 1 day ago
€591
Return
found 1 day ago

Fri, 5 Sep - Fri, 12 Sep
PTY
Panama City
SFO
San Francisco
€599 Return, found 1 day ago
€599
Return
found 1 day ago

Fri, 5 Sep - Fri, 12 Sep
PTY
Panama City
SFO
San Francisco
€612 Return, found 1 day ago
€612
Return
found 1 day ago

Fri, 5 Sep - Fri, 12 Sep
PTY
Panama City
SFO
San Francisco
€623 Return, found 1 day ago
€623
Return
found 1 day ago

Fri, 5 Sep - Fri, 12 Sep
PTY
Panama City
SFO
San Francisco
€745 Return, found 1 day ago
€745
Return
found 1 day ago
Find the cheapest month to fly from Panama City (PTY) to San Francisco (SFO)
August is typically the cheapest month to fly
From €405 - €737 per traveller.
Graph displaying average flight prices per month
Origin airport | Tocumen Intl. |
Destination airport | San Francisco Intl. |
Airlines serving | American Airlines, Copa, United |
Return price | €538 |
Distance | 5313 km |
Average flight time | 5 hours 45 mins |
Perfect flights from Panama City to San Francisco
Embark on an unforgettable journey without breaking the bank with Expedia's incredible deals on cheap flights from Panama City to San Francisco. Whether you're aching for a romantic escape with your partner, craving an adventurous solo expedition, or yearning to immerse yourself in the local history and culture, we've got you covered.
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Our flexible Tocumen Intl. to San Francisco Intl. ticket options cater to your travel preferences, with incredible one-way fares from €353 and roundtrip prices from €538. Whether you're planning a short city break or a longer adventure, our dynamic pricing ensures that you find the best deals for your journey.
But the magic doesn't stop there. Expedia offers a range of partner services to enhance your trip. Rent a car at San Francisco Intl. and explore San Francisco and its surrounding areas at your own pace. Discover hidden gems off the beaten path, and create unforgettable memories. We also provide a handpicked selection of accommodations, from charming bed and breakfasts to luxury hotels, ensuring that you have a comfortable and memorable stay.
Planning your next great adventure is a breeze with Expedia. Our user-friendly platform, unbeatable prices, and round-the-clock customer support are designed to make your travel experience seamless and stress-free. So, why wait? Book your PTY to SFO travel arrangements today and embark on the journey of a lifetime in San Francisco.
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Top Routes from Panama City
Top Routes to San Francisco
- Newark Liberty Intl. Airport to San Francisco (EWR - SFO)
- Los Angeles to San Francisco (LAX - SFO)
- London to San Francisco (LCY - SFO)
- Cork to San Francisco (ORK - SFO)
- Istanbul to San Francisco (IST - SFO)
- New York to San Francisco (JFK - SFO)
- Dublin to San Francisco (DUB - SFO)
- Budapest to San Francisco (BUD - SFO)
- Shannon to San Francisco (SNN - SFO)
- Rome to San Francisco (FCO - SFO)
- Athens to San Francisco (ATH - SFO)
- Lisbon to San Francisco (LIS - SFO)
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