A cityscape with a prominent historical building in the center, surrounded by modern high-rise buildings and a river in the background.

4 Star Hotels in Santa Fe, Santa Fe Province

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Check availability on Santa Fe 4 Star Hotels

Tonight
31 Aug - 1 Sept
Tomorrow
1 Sept - 2 Sept
This weekend
4 Sept - 6 Sept
Next weekend
11 Sept - 13 Sept

Our top choices for Santa Fe 4-star hotels

A spacious lobby with a central circular area, a staircase, and a bar area with multiple seating options.
A multi-story hotel with a curved facade, a central entrance, and a balcony on the upper floors.
A bar area with a floral arrangement and a cocktail on the counter.
A patio area with wooden tables and chairs, a large umbrella, and potted plants.

1. InterTower Hotel

InterTower Hotel
Santa Fe
Canada
Alfred Miels
€104
7 Sept - 8 Sept
InterTower Hotel
A rooftop pool with wooden loungers and a city view.
A restaurant with large windows, indoor plants, and a tiled floor.
An outdoor seating area with white tables and chairs, surrounded by palm trees and greenery, with a modern building in the background.
A modern living room with a sectional sofa, a round coffee table, and a large abstract sculpture.

2. Los Silos Hotel

Los Silos Hotel
Santa Fe
United States
Russell
€112
27 Sept - 28 Sept
Los Silos Hotel
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Learn more about Santa Fe

Discover colonial architecture and vibrant history at Plaza 25 de Mayo, where the Metropolitan Cathedral stands as a stunning centrepiece. Kayak along the Paraná River or visit the riverside Parque del Sur for sunset views across the water.

See all hotels in Santa Fe
A red suspension bridge over a river with surrounding greenery.

Top Santa Fe Hotel Reviews

InterTower Hotel

InterTower Hotel

10/10 Excellent
"We thoroughly enjoyed our stay at the Intertower Hotel and found the staff to be incredibly friendly and helpful. The breakfasts were ample and delicious. The cleaning staff did a superb job. The front desk staff were knowledgeable and very helpful with advice about local things to do. We really liked the option of having two adjoining rooms with the connecting door for our family of five. We would highly recommend!"
Jamin 7-night trip
Posted 2 days ago
InterTower Hotel
Los Silos Hotel

Los Silos Hotel

8/10 Good
"Me gustó las personas que atienden. Todos muy buenos y dedicados a su trabajo."
veronica 3-night trip
Posted 8 days ago
Los Silos Hotel

Frequently asked questions

What are the best 4-star hotels in Santa Fe?
Relax in comfort at InterTower Hotel. According to reviews by our guests, this is one of Santa Fe's best 4-star hotels.
How much does it cost to stay in a 4-star hotel in Santa Fe?
Expedia can help you easily track down the perfect 4-star hotel for your stay in Santa Fe. Use our handy filter tool to tailor your search by things like budget, conveniences and star rating and get access to fantastic deals in a few clicks.
  • Search for the lowest price from €104
What's the difference between 5-star and 4-star hotels in Santa Fe?
Offering a friendly guest experience and upscale surroundings, 4-star hotels are an excellent option for your Santa Fe trip. These kinds of accommodation generally feature lots of useful amenities that make it a breeze to unpack and relax — think pillowtop mattresses, gyms and restaurants. Or live in the lap of luxury at a 5-star hotel designed to pamper with high-end perks and amenities. 24-hour front desk, complimentary toiletries and fine dining are typically featured at these plush properties.

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