A large white building with a dome and a statue in front, surrounded by fountains and trees.

5 Star Hotels in St. Louis, Missouri

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Check availability on St. Louis 5 Star Hotels

Tonight
22 Sept - 23 Sept
Tomorrow
23 Sept - 24 Sept
This weekend
25 Sept - 27 Sept
Next weekend
2 Oct - 4 Oct

Our top choices for St. Louis 5-star hotels

A modern hotel lobby with a glass facade, seating area, and a staircase.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.
A room with large windows overlooking a bridge and water, featuring wooden chairs and a small table.

1. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
United States
Marty
€382
includes taxes & fees
5 Oct - 6 Oct
Four Seasons Hotel St Louis
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A modern living room with a sofa, chairs, a coffee table, and a chandelier.
A lobby with a fireplace, two armchairs, a round table, and a bench.
A bar area with leather seating, a bar counter, and shelves of bottles.

2. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
United States
Kennedy
€650
includes taxes & fees
11 Oct - 12 Oct
The Ritz-Carlton, St. Louis
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in St. Louis.
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road St. Louis MO
€121
11 Oct - 12 Oct
includes taxes & fees
8.4/10 Very good! (1,184 reviews)
Renaissance St. Louis Airport Hotel
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

315 Chestnut St St. Louis MO
€156
2 Oct - 3 Oct
includes taxes & fees
Hyatt Regency St. Louis at The Arch
21C Museum Hotel St Louis

21C Museum Hotel St Louis

1528 Locust street St. Louis MO
€151
18 Oct - 19 Oct
includes taxes & fees
21C Museum Hotel St Louis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

St. Louis and related destinations

The Gateway Arch towers 630 feet above the Mississippi, with a tram that takes you to spectacular views at the top. Explore Forest Park's free museums, catch a Cardinals game at Busch Stadium, and don't miss Ted Drewes' frozen custard that locals swear by.

See all hotels in St. Louis
A large white building with a dome and a statue in front, surrounded by fountains and trees.

Top St. Louis Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in St. Louis?
If you're seeking a 5-star experience, Four Seasons Hotel St Louis offers one of the best of them according to Expedia traveller reviews. Choose this St. Louis getaway and you can look forward to impeccable service, well-appointed guest rooms and top-notch facilities.
How much does it cost to stay in a 5-star hotel in St. Louis?
The amount you pay for a 5-star hotel in St. Louis can vary depending on when you decide to travel and how long you plan to stay, among a number of factors. Take advantage of our price per night filter and other search tools to find the best rate on a high-end stay.
  • Search for the lowest price per night from €121
What makes a hotel 5 stars in St. Louis?
In St. Louis, a hotel needs to provide a specific amount of high-end amenities to be rated 5 stars. These can include saunas and spas, on-site gyms, gourmet restaurants, luxury bathroom products, premium bedding and more. What also sets 5-star hotels apart is their outstanding service. You can expect things like nightly turn-down services, concierge services and in-room massages. Some may even offer additional touches such as welcome gifts.