All hotels in South Carolina Lowcountry, South Carolina
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
All hotels in South Carolina Lowcountry, South Carolina
We have found 13052 South Carolina Lowcountry Hotels
- Marriott's Harbour Point - Hilton Head Island 2 Bedroom Villa
- Sun-Drenched 3BR Villa with Breezy Porch, Lagoon Views, Bikes and Pool Access
- Updated 2BR Condo with Modern Kitchen, Balcony, Pool and Near Local Access
- Oceanfront - 3 Bedroom - Marriott's Monarch at Sea Pines - Full Resort Access
- 2 Bedroom Deluxe Edisto Beach, SC!
- 2 Bedroom Loft. Edisto Beach, SC!
- Savor Peaceful Sunsets Just Steps from the Dock and Serene Waterway Trails
- Group-Friendly 2BR with Lakefront Porch, Kitchen, Tennis, Bikes and Poolside
- Spice Bush at Hilton Head Island is close to Harbour Town and Sea Pines.
- Peaceful Stay w/ Washer, Dryer & Gorgeous Views of the Scenic Coast | 2 Units
- Marriott SurfWatch, 2-bedroom villa Hilton Head, full week only 4/14 to 4/21/24
- Breezy 1BR Condo w/ Pool, Kitchen, Balcony and Just a Quick Stroll to the Beach
- Light-Filled 1BR Escape Near Beach, Dining, Ice Cream Shops and Sunny Pool Days
- Shaded 2BR Nature Escape with Bikes, Porch Lounging and Peaceful Water Backdrop
- Family Beach Week! Hilton Head Coveted 1st Floor Walk Out 2B/2B Villa at Monarch
- 2bed/2bath Lockoff. Edisto Beach, SC!
- 4Bed/3Bath Presidential Unit. Edisto Beach, SC!
- Quiet Oasis w/ Washer & Dryer Just Steps from the Dock and Waterfront Views
- Beautiful House with Beach views
- Marriott Barony Beach, 2BR/2BA Villa w/premier resort amenities & beachfront
- Marriott resort; Ocean Vista, Full kitchen, In and out pools, exercise room.
- Beautiful 3-bedroom oceanfront Marriott Surfwatch resort
- Marriotts SurfWatch - 2 Bedroom, Courtyard View, Sleeps 6
- 2-bedroom resort in charming Hilton Head Island with AC, WiFi, fitness room
- arriott Harbour Point 2025 PGA Tour RBC Heritage Week - 2 Bd, 2 Bath Villa
- 3BR Home w/ Screened Porch, Pool, Tennis, Kitchen, Bike Paths and Water Backdrop
- Nature-Focused 3BR Stay with Porch, Lake Views, Pool, Tennis Courts and Trails
- Spacious 3BR Villa with Pool, Hot Tub, Kitchen and Just a Short Walk to Beach
- Marriott Grande Ocean, Hilton Head Island, SC
- Marriott Grande Ocean, 2BR/2BA Villa w/premier resort amenities & beachfront
- Marriott's Monarch at Sea Pines
- Edisto Island "EDI-Slow" SC King Cotton Villas Resort–3BD/4BA Presidential Suite
- Bluewater Resort 2 bedroom 2 baths kitchen 3 pools- free golf 4 foursome per day
- Bluewater Resort and Marina #2
- 2 Family Suites by the Lazy River – Great for Scenic Views and Relaxing Moments
- 3 Family-Friendly Suites Offering Gorgeous Water Views and a Peaceful Setting
- Dockside Living Awaits in This Elegant Waterfront Escape for All Ages | 2 Units
- Relax in a Serene Spot with Scenic Sunsets Over the Water | 2 Units
- Courtyard View - 3 Bedroom - Marriott's SurfWatch - Full Resort Access
- 2-bedroom Ocean Front Resort Suite - Sleeps 8 - Full Kitchen - Resort Amenities
- Beautiful 2 Bedroom Villa at Marriott Vacation Cub's Hilton Head Harbour Point
- Marriott Sunset Pointe 2025 PGA Tour RBC Heritage Week 2Bd 2 Ba one week booking
- Two Sunny 1BR Getaway w/ Pool Access, Hot Tub, Kitchen and Steps from Ocean Fun
- Marriott’s Harbour Club 2-Bedroom Villas – The Perfect Lowcountry Getaway
- 2 Bedroom - Marriott's Grande Ocean - Ocean View
- Marriott’s Grande Ocean Resort GUARANTEED OCEANFRONT Two BDRM Villa Hilton Head
- Marriott's Monarch on the Beach at Sea Pines with a lovely Garden View
- 2 Bedroom Garden View at Marriott's Monarch at Sea Pines
- 1Bed/1Bath Edisto, SC!
- 4 Bedroom Presidential. Edisto Beach, SC!
- Ideal Location for Scenic Strolls and Peaceful Relaxation by the Water | 3 Units
- Spacious Stay Designed for Laid-Back Family Getaways | 2 Units
- Marriott Barony Beach Resort during the Heritage Golf Tournament, Courtyard View
- Barony Beach Club. A Marriott resort second to none
- Cozy beach front property. Kid friendly!
Let Expedia take you to the best Hotels in South Carolina Lowcountry. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.