A large white dome building with a red brick base, surrounded by green trees and a clear blue sky.

Central Missouri Hotel Guide - Hotels with Spa in Central Missouri, Missouri

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Central Missouri Hotels with Spa

Tonight
8 Oct - 9 Oct
Tomorrow
9 Oct - 10 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

Our top choices for Central Missouri hotels with a spa

A lakeside bar named "FIRE ICE" with outdoor seating and a view of the lake.
A spacious lobby with a high ceiling, stone accents, and a central fireplace.
A lobby with a stone fireplace, seating area, and a view of the sky through the ceiling.
An outdoor seating area with a fire pit, chairs, and a view of a lake at sunset.

1. Lodge Of Four Seasons Golf Resort, Marina & Spa

Lodge Of Four Seasons Golf Resort, Marina & Spa
Lake Ozark
  • Luxurious lakeside retreat with rejuvenating spa treatments and tranquil Japanese gardens for ultimate relaxation.
€101
includes taxes & fees
3 Nov - 4 Nov
Lodge Of Four Seasons Golf Resort, Marina & Spa
A hotel room with two beds, a nightstand, a cabinet, and a wall-mounted artwork.
A marina with docks and a large hotel building in the background.
An aerial view of a marina at dusk with illuminated buildings, docks, and boats.
A group of people dining at an outdoor table with a view of a body of water and city lights in the background.

2. Camden on the Lake Resort & Spa

Camden on the Lake Resort & Spa
Lake Ozark
  • Relax at this lakeside resort with four treatment rooms at Spa 54, featuring hot stone massages, hydrotherapy, and couples' services.
€116
includes taxes & fees
1 Nov - 2 Nov
Camden on the Lake Resort & Spa
A thatched-roof building with a sign reading "TIKI HUT POOL BAR".
Two people sitting on green Adirondack chairs facing a body of water with a forested shoreline in the background.
A spacious lobby with a stone fireplace, comfortable seating, and a large mural on the ceiling.
A deck with a view of a lake, dock, and chairs.

3. Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks
Osage Beach
  • Lakeside spa resort with golf course offers rejuvenating massages, body treatments, and poolside relaxation.
€156
includes taxes & fees
1 Nov - 2 Nov
Margaritaville Lake Resort Lake of the Ozarks
A bar area with wooden counters and stone accents, a stone wall, and a wooden door.
A golf course with a swimming pool and a clubhouse.
A balcony with two chairs and a table, overlooking a golf course and a lake.
A stone gazebo with a stone pathway leading to it, surrounded by well-maintained grass and a pond.

4. The Lodge at Old Kinderhook Golf Resort

The Lodge at Old Kinderhook Golf Resort
Camdenton
  • Revitalise at this lakeside retreat with full-service spa, golf course, and dual pools for ultimate relaxation.
€142
includes taxes & fees
26 Oct - 27 Oct
The Lodge at Old Kinderhook Golf Resort
A room with a bed, a desk with a computer, and a shelf with toiletries.
A historic Courtyard Hotel with large windows, a brick facade, and a welcoming entrance.
A room with a large window, a ceiling fan, a sofa, a table with chairs, and a lamp.
A bar area with a polished wooden counter, a flat-screen TV mounted on the wall, and a framed picture above the counter.

5. The Courtland Hotel and Day Spa

The Courtland Hotel and Day Spa
Fort Scott
  • Tranquil historic hotel offers rejuvenating spa escape with four serene treatment rooms for ultimate relaxation.
€88
includes taxes & fees
2 Nov - 3 Nov
The Courtland Hotel and Day Spa
A spa area with a massage table, a hot tub, and a grill.
A row of houses with a driveway leading to a gated entrance.
A living room with a fireplace, a dining area with a round table, and a balcony with a view.
A hot tub, a fire pit, and a view of a lake.

6. Hermann Hill

Hermann Hill
Hermann
  • Riverside bed and breakfast with private hot tubs and spa treatments offers romantic rejuvenation.
€337
includes taxes & fees
2 Nov - 3 Nov
Hermann Hill
View all properties

Choose what matters most at spa hotels in Central Missouri

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Central Missouri Hotel Reviews

Margaritaville Lake Resort Lake of the Ozarks

Margaritaville Lake Resort Lake of the Ozarks

10/10 Excellent
"We enjoyed our family stay in July. Lots of things for everyone in the family to do. The pools got very busy and we're hard to find a place to enjoy, but throughout the rest of the stay there was plenty that kept everyone happy! The painting class was super fun, we had drinks at several bars, food at Fin City and Landsharks, went bowling, visited the gym, used the indoor hot tub, played in the arcade, had brunch with mimosa, and just enjoyed our weekend. We will definitely be back!"
Heather 3-night trip
Posted 9 hours ago
Margaritaville Lake Resort Lake of the Ozarks
Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

10/10 Excellent
"Everything was clean and staff was friendly. Enjoyed the pool and hot tub. Good variety free breakfast. Only two issues, toilet didn't always flush properly and there was no coffee to fix a cup to go on my way out at checkout."
Linda 2-night trip
Posted 11 hours ago
Wingate by Wyndham - Columbia
Country Inn & Suites by Radisson, Columbia, MO

Country Inn & Suites by Radisson, Columbia, MO

10/10 Excellent
"Excellent bfst"
Ronald 1-night trip
Posted 16 hours ago
Country Inn & Suites by Radisson, Columbia, MO

Explore a world of travel with Expedia