Walterboro Hotel Guide - Colleton Medical Center hotels in Walterboro, United States of America.

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20 Dec - 21 Dec
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Our top choices for Colleton Medical Center hotels

Free daily on-the-go breakfast
Sleep Inn Walterboro I-95

Sleep Inn Walterboro I-95

Sleep Inn Walterboro I-95
2.5 star property
2 km from Colleton Medical Center
7.6 out of 10, Good, (575)
"Quiet and very accesible place."
United States
Lisa
The price is €76
includes taxes & fees
13 Jan - 14 Jan 2026
Sleep Inn Walterboro I-95
Standard Room, 1 King Bed
Southern Inn By OYO Walterboro I-95

Southern Inn By OYO Walterboro I-95

Southern Inn By OYO Walterboro I-95
2.5 star property
1.8 km from Colleton Medical Center
7.0 out of 10, Good, (79)
"Room is badly overrated. Sink was clogged. Interior badly needs remodeled."
United States
Ronnie
The price is €49
includes taxes & fees
28 Dec - 29 Dec
Southern Inn By OYO Walterboro I-95
Front of property – evening/night
Travelodge by Wyndham Walterboro

Travelodge by Wyndham Walterboro

Travelodge by Wyndham Walterboro
2.0 star property
1.8 km from Colleton Medical Center
6.2 out of 10, (527)
"Everything is ok "
United States
Fonda
The price is €52
includes taxes & fees
21 Dec - 22 Dec
Travelodge by Wyndham Walterboro
Exterior
Super 8 by Wyndham Walterboro

Super 8 by Wyndham Walterboro

Super 8 by Wyndham Walterboro
2.0 star property
2.3 km from Colleton Medical Center
6.2 out of 10, (211)
"Stay was good. "
United States
Cindy
The price is €58
includes taxes & fees
27 Dec - 28 Dec
Super 8 by Wyndham Walterboro
Free daily buffet breakfast
Hampton Inn & Suites Walterboro

Hampton Inn & Suites Walterboro

Hampton Inn & Suites Walterboro
2.5 star property
6.9 km from Colleton Medical Center
9.2 out of 10, Wonderful, (1000)
"Wonderful stay!"
United States
Efrain
The price is €152
includes taxes & fees
23 Dec - 24 Dec
Hampton Inn & Suites Walterboro
Desk, iron/ironing board, free WiFi, bed sheets
Comfort Inn & Suites Walterboro I-95

Comfort Inn & Suites Walterboro I-95

Comfort Inn & Suites Walterboro I-95
2.5 star property
6.6 km from Colleton Medical Center
8.6 out of 10, Excellent, (1002)
"Room is clean and staff was very courteous and check in was a breeze. Would stay here again"
United States
Teddy
The price is €102
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn & Suites Walterboro I-95
Free daily buffet breakfast
Holiday Inn Exp Walterboro by IHG

Holiday Inn Exp Walterboro by IHG

Holiday Inn Exp Walterboro by IHG
2.5 star property
6.8 km from Colleton Medical Center
8.6 out of 10, Excellent, (1003)
"Big room and friendly staff. Breakfast was great "
United States
Michael
The price is €142
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Exp Walterboro by IHG
Free WiFi, bed sheets
Motel 6 Walterboro, SC

Motel 6 Walterboro, SC

Motel 6 Walterboro, SC
2.0 star property
6.6 km from Colleton Medical Center
8.2 out of 10, Very good, (1418)
"Room was spotless and the staff was excellent. Would love to stay here again. "
United States
Tina
The price is €53
includes taxes & fees
22 Dec - 23 Dec
Motel 6 Walterboro, SC
Breakfast area
Econo Lodge Walterboro I-95

Econo Lodge Walterboro I-95

Econo Lodge Walterboro I-95
2.0 star property
5.9 km from Colleton Medical Center
7.8 out of 10, Good, (1001)
"Great motel and great prices "
United States
Kent
The price is €50
includes taxes & fees
28 Dec - 29 Dec
Econo Lodge Walterboro I-95
Exterior
Microtel Inn & Suites by Wyndham Walterboro

Microtel Inn & Suites by Wyndham Walterboro

Microtel Inn & Suites by Wyndham Walterboro
2.0 star property
6.9 km from Colleton Medical Center
8.0 out of 10, Very good, (1001)
"Clean, great staff, no eggs or meat at breakfast, small bathroom vanity "
United States
Laura
The price is €90
includes taxes & fees
5 Jan - 6 Jan 2026
Microtel Inn & Suites by Wyndham Walterboro
Lobby
Best Western Of Walterboro

Best Western Of Walterboro

Best Western Of Walterboro
2.5 star property
6.3 km from Colleton Medical Center
7.6 out of 10, Good, (338)
"Room was very clean and quiet. Easy check in and check out. "
United States
Jessica
The price is €75
includes taxes & fees
23 Dec - 24 Dec
Best Western Of Walterboro
Free daily buffet breakfast
Quality Inn Walterboro I-95

Quality Inn Walterboro I-95

Quality Inn Walterboro I-95
2.5 star property
6.8 km from Colleton Medical Center
7.6 out of 10, Good, (864)
"It was so nice we booked additional week. "
United States
R
The price is €67
includes taxes & fees
30 Dec - 31 Dec
Quality Inn Walterboro I-95
Lobby
Days Inn by Wyndham Walterboro

Days Inn by Wyndham Walterboro

Days Inn by Wyndham Walterboro
2.0 star property
6.8 km from Colleton Medical Center
7.2 out of 10, Good, (766)
"It was just ok"
United States
Julie
The price is €60
includes taxes & fees
23 Dec - 24 Dec
Days Inn by Wyndham Walterboro
Standard Room, 2 Double Beds, Smoking | Room amenity
Rodeway Inn Walterboro I-95

Rodeway Inn Walterboro I-95

Rodeway Inn Walterboro I-95
2.0 star property
6.4 km from Colleton Medical Center
7.0 out of 10, Good, (259)
"The AC worked hgreat, .my room was clean and the staff was friendly. "
United States
Tammy
The price is €45
includes taxes & fees
4 Jan - 5 Jan 2026
Rodeway Inn Walterboro I-95
Premium bedding, desk, soundproofing, iron/ironing board
Red Roof Inn Walterboro

Red Roof Inn Walterboro

Red Roof Inn Walterboro
2.0 star property
6.1 km from Colleton Medical Center
6.6 out of 10, (860)
"Always stay here on our way to the mountains "
United States
Judy
The price is €52
includes taxes & fees
1 Jan - 2 Jan 2026
Red Roof Inn Walterboro
Front of property – evening/night
Baymont by Wyndham Walterboro

Baymont by Wyndham Walterboro

Baymont by Wyndham Walterboro
2.5 star property
6.2 km from Colleton Medical Center
6.2 out of 10, (1045)
"I like the quietness. "
United States
Joseph
The price is €47
includes taxes & fees
21 Dec - 22 Dec
Baymont by Wyndham Walterboro
Reception
Budgetel

Budgetel

Budgetel
2.0 star property
6 km from Colleton Medical Center
3.6 out of 10, (5)
"There was bedbugs! Tim was very friendly though. "
United States
Abu
The price is €67
includes taxes & fees
21 Dec - 22 Dec
Budgetel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Colleton Medical Center Hotel Reviews

Comfort Inn & Suites Walterboro I-95

Comfort Inn & Suites Walterboro I-95

10/10 Excellent
"Nice clean room Easy access to I95"
Michael 1-night trip
Posted 6 days ago
Comfort Inn & Suites Walterboro I-95

Hotels near other Colleton Medical Center attractions

First Baptist Church

3.9/5 (30 reviews)
After visiting First Baptist Church, make a plan to see the other sights and activities in Walterboro. While you're here, you can savour the top-notch restaurants.
See properties

Forest Hills Tennis Center

Catch an event at Forest Hills Tennis Center during your trip to Walterboro. While you're here, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Colleton Medical Center?
Colleton Medical Center is located in Walterboro. This welcoming area is known for its array of dining options. You'll find 35 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay near Colleton Medical Center?
Baymont by Wyndham Walterboro is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. It's located 3.9 mi (6.2 km) from Colleton Medical Center. Other good options within 5 miles include Comfort Inn & Suites Walterboro I-95 and Motel 6 Walterboro, SC.
How many hotels should I expect to find close to Colleton Medical Center?
Expedia has 35 hotels and other accommodation options a few miles from Colleton Medical Center.
If I need to cancel the hotel reservation for my stay near Colleton Medical Center, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, you might be able to still cancel and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to get the best options available near Colleton Medical Center.