A historic stone fortress with a central dome and surrounding walls.

Colon Hotel Guide - Luxury Hotels in Colon, Colón

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Check availability on Colon Luxury Hotels

Tonight
3 Oct - 4 Oct
Tomorrow
4 Oct - 5 Oct
Next weekend
9 Oct - 11 Oct
In two weeks
16 Oct - 18 Oct

Our top choices for Colon luxury hotels

A hotel entrance with a central water feature, seating areas, and potted plants.
An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.
A pool with a central water feature, surrounded by seating areas and potted plants.
The entrance of The Santa Maria with a covered walkway and a view of the interior.

1. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
  • Elevate your Panama City escape with a Jack Nicklaus golf course, rejuvenating spa treatments, and poolside luxury at this 5-star retreat.
€227
includes taxes & fees
31 Oct - 1 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A Courtyard Marriott hotel with a parking lot, palm trees, and a city skyline in the background.
An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.
A buffet with various food items including fruits, juices, and cheeses.
A hotel reception area with a wooden reception desk, seating area with chairs and ottomans, and a large window providing natural light.

2. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
€99
includes taxes & fees
23 Oct - 24 Oct
Courtyard by Marriott Panama Metromall
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
An indoor swimming pool with lounge chairs and red chairs, surrounded by lush greenery and a modern interior design.
A modern hotel entrance with a prominent 'Renaissance Hotel' sign, a well-lit outdoor area with a wooden structure, and a staircase leading to the upper floors.
A modern lobby with a staircase, marble flooring, and large windows with tropical plants.

3. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
  • Lavish escape in city centre Panama City with an outdoor pool, casino thrills, and fine dining, all minutes from top attractions.
€124
includes taxes & fees
10 Oct - 11 Oct
Renaissance Panama City Hotel
A rooftop pool with clear blue water, surrounded by palm trees and a city skyline in the background.
An outdoor café with multiple wooden tables and chairs, surrounded by greenery and decorative elements.
A modern hotel room with a large bed, a wardrobe, a desk with a chair, and a decorative wall piece.
A restaurant with wooden tables and chairs, hanging plants, and circular wall decorations.

4. Gran Evenia Panama

Gran Evenia Panama
Bella Vista
  • Indulge in luxurious comfort at this Panama hotel featuring rainfall showers, premium dining, and a stunning outdoor pool.
€99
includes taxes & fees
4 Oct - 5 Oct
Gran Evenia Panama
A poolside area with lounge chairs and a view of the ocean.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A terrace with seating and a view of the ocean.

5. JW Marriott Panama

JW Marriott Panama
San Francisco
  • Unwind in opulent waterfront luxury with 4 pristine pools and ocean-view dining in Panama City.
€265
includes taxes & fees
31 Oct - 1 Nov
JW Marriott Panama
A spacious indoor area with high ceilings, large windows, and multiple dining tables.
A restaurant with brick walls, arched windows, and a variety of seating arrangements including tables and chairs.
A spacious lobby with a tiled floor, large windows, and potted plants.
A white building with multiple balconies, large windows, and decorative railings.

6. American Trade Hotel

American Trade Hotel
Casco Viejo
  • A colonial gem in Panama City offering luxurious comfort, exquisite dining, and personalised service in a historic district.
€175
includes taxes & fees
13 Oct - 14 Oct
American Trade Hotel
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.
A modern hotel room with a dining area, a TV, and a city view.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.

7. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
  • Exclusive Panama City escape offers lavish poolside retreats and gourmet dining experiences.
€135
includes taxes & fees
25 Oct - 26 Oct
Hotel Riu Plaza Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.
A hotel with a rooftop pool, lounge chairs, and a view of the sea.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.

8. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
  • Indulge in colonial elegance at this Panama City gem featuring a full-service spa, outdoor pool, and gourmet dining.
€343
includes taxes & fees
3 Nov - 4 Nov
Sofitel Legend Casco Viejo, Panama City
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.
A modern building with a sign reading 'HYATT REGENCY.'
A modern interior with a central seating area, potted plants, and a staircase.

9. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
  • Indulgence awaits in this 4.5-star Panama City sanctuary featuring a full-service spa, outdoor pool, and elegant dining near Via Espana.
€183
includes taxes & fees
11 Oct - 12 Oct
Hyatt Regency Panama City
A restaurant with multiple dining tables, chairs, and a central water feature.
A historic building with ornate stonework and a balcony with plants.
A modern living room with a sofa, a coffee table, and a TV mounted on the wall.
A rooftop terrace with tables and chairs, a view of two white towers, and a building with a large window.

10. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
Casco Viejo
  • Experience historic luxury in Panama's Casco Viejo district with 5 restaurants and a rooftop pool with spectacular views.
€257
includes taxes & fees
9 Oct - 10 Oct
Hotel La Compañía Casco Antiguo
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Top Colon Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Si"
Otto 1-night trip
Posted 7 hours ago
Hotel Riu Plaza Panama
Gamboa Rainforest Reserve

Gamboa Rainforest Reserve

10/10 Excellent
"Incredibly friendly staff and there’s enough activities offered by this hotel to keep you busy for a few days. Really enjoyed my stay."
Hazel 3-night trip
Posted 16 hours ago
Gamboa Rainforest Reserve
Decapolis Hotel Panama City

Decapolis Hotel Panama City

10/10 Excellent
"Excellent hotel with a convenient price with the breakfast included."
Armando Bey 1-night trip
Posted 19 hours ago
Decapolis Hotel Panama City
Hotel Ojos del Rio

Hotel Ojos del Rio

8/10 Good
"No hot water in the shower."
charles 2-night trip
Posted 4 days ago
Hotel Ojos del Rio

Frequently asked questions

Are you looking for a luxury hotel for your Colon holiday?
Use Expedia to arrange your flight to Panama City (PAC-Marcos A. Gelabert Intl.) airport or Balboa (BLB-Panama Pacifico Intl.) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are important when you plan a trip, so we make it easy to find what you'd like to make your stay relaxing and comfortable. If you want an upscale hotel with a spa, an indoor pool or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Colon offers. Colon has some interesting things to see and do including Colon 2000 and Colon Free Zone, so you might want to take in the local sights during your visit.
What's the best luxury place to stay in Colon?
Sand Diamond Hotel is a luxury hotel with ski-in/ski-out access and a casino, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in Colon?
Planning for the weather is an important factor for making your trip to Colon a success, especially when you're splurging. The hottest months are usually May and September, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Colon are November, July, August and October, with each month seeing an average of 350 mm of rainfall.
What's there to see and do in Colon?
Take in the sights and attractions that Colon offers with a visit to Colon 2000, Colon Free Zone and Gamboa Rainforest Resort. If you have extra time while you're in the area, you might want to see Fantastic Casino | Colón 2000 and Fort San Lorenzo.
How can I get around Colon?
It's easier to get around town in style when you know your options. If you want to venture outside the area, hop aboard a train at Colon Atlantic Passenger Station.