Commerce
Travel Guide
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Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
The price is €87 per night from 9 Nov to 10 Nov
€87
9 Nov - 10 Nov
includes taxes & fees
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,009 reviews)
"Loved having breakfast, hot meal and drinks as part of our stay"
Reviewed on 5 Oct 2025

The Riverview
777 Main St, Cape Girardeau, MO
The price is €112 per night from 19 Oct to 20 Oct
€112
19 Oct - 20 Oct
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.2/10 Wonderful! (432 reviews)
"Newer hotel so clean. Walk-in shower with no door but works. Control is on opposite side of shower head so alittle awkward. Starbucks was nice. Front desk very accommodating. Close to old downtown but too far to walk. Railroad tracks on east side but didn’t reallly hear."
Reviewed on 7 Oct 2025

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3003 SOUTH OLD ORCHARD ROAD, Jackson, MO
The price is €78 per night from 21 Oct to 22 Oct
€78
21 Oct - 22 Oct
includes taxes & fees
Stay at this 3-star business-friendly hotel in Jackson. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (634 reviews)
"Clean"
Reviewed on 8 Oct 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Peaceful secluded cabin located near Horseshoe Lake
Miller City
Stay at this cabin in Alexander County. Enjoy an in-room coffeemaker and air conditioning.
9.8/10 Exceptional! (18 reviews)
"cute A frame in a secluded spot. Couldn’t ask for a more relaxing situation."
Reviewed on 31 Aug 2025

Serenity South -- Gardens, River-Views, and Refreshing Space
Cape Girardeau
Book a stay at this family-friendly vacation home in Cape Girardeau. Enjoy a water park, a garden, and patios. Popular attractions eDen Spa & Salon and The Glenn ...
10/10 Exceptional! (141 reviews)
"Good stay."
Reviewed on 30 Sept 2025

The Twisted Sassafras Treehouse
Cape Girardeau
Stay at this cabin in Cape Girardeau. Enjoy a garden, patios, and an in-room coffeemaker. Popular attractions Cape Girardeau Conservation Nature Center and Cape ...
10/10 Exceptional! (24 reviews)
"Amazing space. So nice being up in the trees. Had an amazing, relaxing time!!!"
Reviewed on 20 Sept 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.