Photo by Bill Dillard

Search Guadalupe County Hotels

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Top Cities in Guadalupe County

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Guadalupe County hotels

La Quinta Inn & Suites by Wyndham Santa Rosa

La Quinta Inn & Suites by Wyndham Santa Rosa
3.0 star property
Santa Rosa
9.2 out of 10, Wonderful, (1439)
"The room and property were very clean. The blankets are a little thin but other than that it was great for our nights stay. The staff was very friendly and the breakfast was good. Will absolutely stay there again. "
United States
Ricky
The price is €139
includes taxes & fees
29 Dec - 30 Dec
La Quinta Inn & Suites by Wyndham Santa Rosa

Super 8 by Wyndham Santa Rosa

Super 8 by Wyndham Santa Rosa
2.0 star property
Santa Rosa
7.8 out of 10, Good, (1001)
"Nice, clean and quiet hotel. "
United States
Michelle
The price is €67
includes taxes & fees
1 Jan - 2 Jan 2026
Super 8 by Wyndham Santa Rosa

Comfort Inn Santa Rosa on Route 66

Comfort Inn Santa Rosa on Route 66
2.5 star property
Santa Rosa
8.4 out of 10, Very good, (1007)
"Loved staying here"
United States
Daniel
The price is €109
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Inn Santa Rosa on Route 66

Days Inn & Suites by Wyndham Santa Rosa

Days Inn & Suites by Wyndham Santa Rosa
2.0 star property
Santa Rosa
8.6 out of 10, Excellent, (541)
"Clean room, friendly staff and very convenient parking arrangements"
United States
Evon
The price is €88
includes taxes & fees
1 Jan - 2 Jan 2026
Days Inn & Suites by Wyndham Santa Rosa

Hampton Inn Santa Rosa

Hampton Inn Santa Rosa
2.5 star property
Santa Rosa
8.4 out of 10, Very good, (937)
"Thank you everything was nice"
United States
Chandra
The price is €110
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Santa Rosa

Best Western Santa Rosa Inn

Best Western Santa Rosa Inn
2.5 star property
Santa Rosa
9.2 out of 10, Wonderful, (1003)
"Friendly front desk, dog friendly grounds close to restaurant."
Canada
Robyn
The price is €135
includes taxes & fees
24 Dec - 25 Dec
Best Western Santa Rosa Inn

Hotel Blue 66, BW Signature Collection

Hotel Blue 66, BW Signature Collection
2.5 star property
Santa Rosa
8.4 out of 10, Very good, (184)
"Excellent hotel for the value. Super clean, good decor, excellent wifi, good breakfast choices. Glad to have found this little gem."
Canada
Sylvie
The price is €90
includes taxes & fees
30 Dec - 31 Dec
Hotel Blue 66, BW Signature Collection

Motel 6 Santa Rosa, NM

Motel 6 Santa Rosa, NM
2.0 star property
Santa Rosa
6.6 out of 10, (1004)
"Room was clean."
United States
Emily
The price is €62
includes taxes & fees
1 Jan - 2 Jan 2026
Motel 6 Santa Rosa, NM

Econo Lodge Inn & Suites Santa Rosa

Econo Lodge Inn & Suites Santa Rosa
2.0 star property
Santa Rosa
8.6 out of 10, Excellent, (1004)
"Nice place to stay "
United States
Michelle
The price is €77
includes taxes & fees
1 Jan - 2 Jan 2026
Econo Lodge Inn & Suites Santa Rosa

Holiday Inn Express SANTA ROSA by IHG

Holiday Inn Express SANTA ROSA by IHG
2.5 star property
Santa Rosa
8.4 out of 10, Very good, (1000)
"Excellent breakfast!"
United States
Louella
The price is €137
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express SANTA ROSA by IHG

Route 66 Inn

Route 66 Inn
2.5 star property
Santa Rosa
5.0 out of 10, (130)
"Pet friendly, room in the parking lot if you are traveling with a trailer or motorhome. The office is open 24/7. "
United States
Christine
The price is €62
includes taxes & fees
4 Jan - 5 Jan 2026
Route 66 Inn

Travelodge by Wyndham Vaughn

Travelodge by Wyndham Vaughn
2.0 star property
Vaughn
6.2 out of 10, (220)
"It was clean n nice , quite staf was great"
United States
Dolores
The price is €117
includes taxes & fees
9 Jan - 10 Jan 2026
Travelodge by Wyndham Vaughn

Rodeway Inn Santa Rosa

Rodeway Inn Santa Rosa
2.0 star property
Santa Rosa
6.0 out of 10, (478)
"The staff is very helpful and the room is clean and excellent condition. "
United States
Shirley
The price is €68
includes taxes & fees
1 Jan - 2 Jan 2026
Rodeway Inn Santa Rosa

Americas Best Value Inn Santa Rosa, NM

Americas Best Value Inn Santa Rosa, NM
2.0 star property
Santa Rosa
7.6 out of 10, Good, (1002)
"Very kind and courteous staff. Clean room and everything we needed. Very pleased with our stay. "
United States
Suzanne
The price is €67
includes taxes & fees
7 Jan - 8 Jan 2026
Americas Best Value Inn Santa Rosa, NM

Charming Santa Rosa Home w/ Mountain Views & Porch

Charming Santa Rosa Home w/ Mountain Views & Porch
3.0 star property
Santa Rosa
10.0 out of 10, Exceptional, (1)
"Overall amazing!!!"
United States
Christopher
Charming Santa Rosa Home w/ Mountain Views & Porch

Rodeway Inn Santa Rosa, NM

Rodeway Inn Santa Rosa, NM
2.0 star property
Santa Rosa
2.0 out of 10, (1)
"Dog and human hair all over bed, bath drain plugged, shower valve broken, mold at every wall/ceiling/floor corner, bed hard as a rock, breakfast was not worth trying cold cereal or a boiled egg. Coffee area was filthy. Sugar packets had been doused in something and were all hard and stained. Pass. Not worth even the lower price compared to La Quint across the street. "
United States
Gary
Rodeway Inn Santa Rosa, NM

Sunset Motel

Sunset Motel
2.0 star property
Santa Rosa
4.4 out of 10, (12)
"Nothing, it was terrible! Office was closed, no one answered the phone. Attempted several times. Drapes falling, old furniture on plain view, motel appeared abandoned and unhabitable. After 2 hours of waiting, I left and continue my travel."
United States
JacquelineReyes
Sunset Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Guadalupe County Hotel Reviews