Photo by Caitlyn McCrimmon

Holiday Rentals in Los Santos

Save an average of 15% on thousands of properties with Expedia Rewards

Most properties are fully refundable. Because flexibility matters.

Search over 2.9 imllion properties and 550 airlines worldwide

Featured Holiday Rentals in Los Santos

Front of property
Villas Don Pablo
1.0 star property
9.4 out of 10, Exceptional, (7)
"Ofrece todo lo necesario para una familia, en un ambiente seguro y tranquilo. "
The price is €51
per night
18 May - 19 May
Villas Don Pablo
Pool
PEDASI - BEACHFRONT POOL ENTIRE VILLA - 3BRM HOUSE - Ranch Style + Fishing too.
10.0 out of 10, Exceptional, (1)
"Great for long walks on beach and shaded pool. Basic kitchen - we enjoyed our breakfasts and lunches at the house. Esteban is a wonderful host - very responsive and helpful. Comes with Bailey the Fox Hound - great beach buddy!"
PEDASI - BEACHFRONT POOL ENTIRE VILLA - 3BRM HOUSE - Ranch Style + Fishing too.
Boating
Hostal Pachamama
1.5 star property
10.0 out of 10, Exceptional, (1)
"Großartige Erfahrung! Absolute Ruhe und Einsamkeit. Die Gastgeber tun alles, um den Aufenthalt zu einem wunderschönen Erlebnis werden zu lassen. Die Hütten sind sehr einfach aber es ist alles vorhanden, was man dringend braucht! Vielen Dank nochmal!!"
The price is €44
per night
21 May - 22 May
Hostal Pachamama
Save an average of 15% on thousands of hotels when you're signed in
Outdoor pool
Beautiful Casita with Ocean front infinity pool.
10.0 out of 10, Exceptional, (2)
"Wonderful and relaxing stay. As advertised. Bonnie was the absolute best host! Highly recommend!"
Beautiful Casita with Ocean front infinity pool.
Property grounds
Beautiful Beach House in Las Tablas Panama
9.2 out of 10, Wonderful, (5)
"Everything was as advertised, great location with a beautiful view. This is our second year staying here and there were several upgrades that made our stay better. Looking forward to our next visit to the beach."
Beautiful Beach House in Las Tablas Panama
Outdoor pool
Beautiful Villa in Pedasi, Beach View.
10.0 out of 10, Exceptional, (5)
"Location was great and the accommodations were spacious. The pool was a lifesaver!"
Beautiful Villa in Pedasi, Beach View.
Outdoor pool
Resting cabin with a unique garden, swimming pool and Panamanian traditions.
10.0 out of 10, Exceptional, (1)
"La experiencia fue hermosa, estar en el lugar es mucho más bello que en las fotos, los colores, las plantas, el aire 100, la piscina 100, tiene calentador de agua, cocina cómoda, las camas cómodas y muy gratificante las conversaciones con la Sra. Doris y Sr. Juan, espacio para estacionar, hay un restaurante muy cerca para las cenas se llama “Snack” tiene menú con pescados, mariscos y carnes, todo muy bueno y súper bien precio….. excelente experiencia!"
Resting cabin with a unique garden, swimming pool and Panamanian traditions.
Pool
El Sitio Villas
3.5 star property
8.6 out of 10, Excellent, (4)
"The hotel and staff are fantastic and we had a wonderful time. But I am unhappy with the $1000 deposit required at check in. First I find it far too high and second the process to refund it was very strange. At check in they charged my credit card $1000 and then at check out they said they had to run it again for another $1000 before they could refund the original $1000. None of this made any sense to me and I was left with two $1000 receipts and only one showing a refund of $1000. I don't...
The price is €191
per night
16 Jun - 17 Jun
El Sitio Villas
An infinity pool
Amazing Blue Venao, Unique & Cozy 2BR Condo — 3 min from the beach!
10.0 out of 10, Exceptional, (3)
"This is a very modern, beautiful main floor condo in the heart of the surfing area of Playa Venao. It provides a very accommodating arrangement for up to 4 people with two comfortable bedrooms, a well equipped full kitchen and lovely large partially covered outdoor patio. Paulo (owner) has ensured your stay will be comfortable in every way! The facilities at Blue Venao are excellent including a beautiful large pool overlooking the beach, yoga classes and several restaurants each with amazing...
Amazing Blue Venao, Unique & Cozy 2BR Condo — 3 min from the beach!
Outdoor pool
Villa Nomada
3.5 star property
10.0 out of 10, Exceptional, (3)
"Muy bonita casa frente al mar, amplias recamaras, detalles muy agradables, cocina amplia y de alta calidad. La piscina perfecta y un ambiente muy agradable. Perfecto para ir unos dias en familia o grupo de amigos. Definitivamente un lugar para repetir. Excelente! A mi familia de USA y de aquí de Panamá les encantó."
The price is €559
per night
19 May - 20 May
Villa Nomada
Sports facility
Playa Blanca Vacations Rentals
3.5 star property
7.4 out of 10, Good, (52)
"It’s nice view a huge man made lake and ocean - But rooms A/C did not cool place down so we had to pay additional charge to move to hotel with A/C while still facing the heat in doors"
The price is €177
per night
27 May - 28 May
Playa Blanca Vacations Rentals
Outdoor pool
Modern Thematic Apartment in Playa Blanca Panama
8.0 out of 10, Very good, (1)
"It was spotless and the owner was super responsive to any questions I had, right away! The property needs little things here and there Nighttables (none in the Master) Trash cans in bathrooms No cutlery knives (perhaps someone took them???) Detailed instructions on Wifi, TV, oven, would be nice. Had to reach out a few times to figure things out."
The price is €199
per night
21 May - 22 May
Modern Thematic Apartment in Playa Blanca Panama
Pool
Peaceful Oasis at Nikki Residences, Playa Blanca
8.8 out of 10, Excellent, (8)
"Very quiet beach and general area! Absolutely no fight for chairs . Enjoyed the available food ,bar and music thurs Fri, sat and sun. The pool is beautiful large and clean . Amenities/gym not as indicated in VRBO . Gym is not available. It has been neglected and needs a significant amount of work to reopen. Despite some vacant and neglected condos, it is a place I would love to return ."
Peaceful Oasis at Nikki Residences, Playa Blanca
On the beach
Newly remodeled Town Center condo Resort. Saltwater pool and water slide LUXURY
Newly remodeled Town Center condo Resort. Saltwater pool and water slide LUXURY
Outdoor pool
Beach House / 6 People / Pool / Pet Friendly / Tourist Area
8.0 out of 10, Very good, (1)
"Todo muy bien ordenado y cómodo. Buena comunicación con la anfitriona."
Beach House / 6 People / Pool / Pet Friendly / Tourist Area
Outdoor pool
Terreza Villas - Beach Front Villa
6.0 out of 10, (1)
"Days before I arrived, the host emailed me and asked if I minded switching rooms because current occupants wanted to extend their stay. I said okay. When I arrived, nothing was ready and I tried to communicate to the onsite staff that I was supposed to be in the upstairs unit. After waiting an hour I was led to a room that was not clean. I spent the first night without towels or toilet paper. Finally the next afternoon, I got the keys to the proper room. I asked for a refund for the 1st night,...
Terreza Villas - Beach Front Villa
View from property
Terrazas Villa Beach Front
2.0 out of 10, (1)
"Que me fue cancelada mi reserva y no se me llamo para indicármelo."
Terrazas Villa Beach Front
Beach
Panama Santa Clara Beach Residence
9.6 out of 10, Exceptional, (4)
"The house worked well for our two families traveling together. There were plenty of comfortable beds. The bedrooms have air conditioning. The outdoor space was great. The kids enjoyed the pool, basketball hoop, pool table and ping pong table. Benito was very helpful with the house. We did have water issues but Benito took care of our issues. Overall the house had everything we needed but was very basis. We enjoyed our stay. "
Panama Santa Clara Beach Residence
Outdoor pool
BEAUTIFUL LUXURY VILLA 3 BEDROOMS
The price is €232
per night
20 May - 21 May
BEAUTIFUL LUXURY VILLA 3 BEDROOMS
Private kitchen
Loft Style Medieval Tranquilite Assure a 1 km de la Plage
The price is €101
per night
17 May - 18 May
Loft Style Medieval Tranquilite Assure a 1 km de la Plage
Don't see what you're looking for?
See all available properties in Los Santos
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Holiday Homes in Los Santos

Search for holiday homes in Los Santos on Expedia.ie! You can easily find your home rentals, villas, holiday apartments in Los Santos using one of the methods below: 

  • View our selection of featured holiday homes in Los Santos
  • Use the map to find apartments and other holiday rentals in the Los Santos neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday homes in Los Santos while they last

Look no further and take a look at our great range of rental properties in Los Santos!

Recent reviews in Los Santos
Expedia verified reviews