A coastal landscape with clear turquoise waters, sandy beaches, and volcanic hills.

Holiday Rentals in Santa Cruz

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Our top choices for Santa Cruz holiday rentals

1. Torre Mar Galapagos Boutique Suites

Torre Mar Galapagos Boutique Suites
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (28 reviews)
"The host was so nice, kind, and friendly."
United States
Maho
The price is €117
12 Oct - 13 Oct
Torre Mar Galapagos Boutique Suites

2. VILLA MICONIA

VILLA MICONIA
3.0 star property
San Cristobal
The price is €143
12 Oct - 13 Oct
VILLA MICONIA

3. Modern apartment with 18 feet ceilings and private terrace with view to a park

Modern apartment with 18 feet ceilings and private terrace with view to a park
Puerto Ayora
10.0 out of 10, Exceptional, (24 reviews)
"I highly recommend you stay here. Its is beautiful and also away from the crowd noise."
United States
Richard
The price is €140
12 Oct - 13 Oct
Modern apartment with 18 feet ceilings and private terrace with view to a park

4. Suites

Suites
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (25 reviews)
"Check was early and friendly staff Room was super clean and comfortable"
United States
Judy
The price is €74
12 Oct - 13 Oct
Suites

5. Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (2 reviews)
"The place is perfect in every way, clean , spacious, great kitchen, comfortable beds, also the laundry facility is so helpful for longer stay. The host communication is excellent, immediate responds, great recommendations for the activities and local eats, location is also good , 10-15 minutes to walk to town center. we enjoyed our stay very much. highly recommend this place."
United States
Lihua
The price is €199
12 Oct - 13 Oct
Chic City Gateway: Spacious modern apartment in the Heart of Puerto Ayora

6. Colmena Apartment in downtown Puerto Ayora, Santa Cruz

Colmena Apartment in downtown Puerto Ayora, Santa Cruz
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We had an excellent experience at Five minutes from the malecon Santa Cruz - Puerto Ayora. The property is brand new, very secure, and perfectly located. What truly made our stay special was our host, Gaby. She was always available, attentive, and ready to help us with anything we needed. Had we known about this place earlier, we would have booked it for our entire stay in Santa Cruz. We highly recommend this accommodation to anyone visiting the island — it’s a gem!"
United States
jacques
The price is €163
12 Oct - 13 Oct
Colmena Apartment in downtown Puerto Ayora, Santa Cruz

7. Galapagos Family Vacation 3 BR. Centrally located and Ocean View

Galapagos Family Vacation 3 BR. Centrally located and Ocean View
Puerto Ayora
10.0 out of 10, Exceptional, (28 reviews)
"Great communication with host, gave us information ahead of time for laundry services and taxi. Clean and wonderful property close to everything and great views."
United States
Amanda
The price is €401
12 Oct - 13 Oct
Galapagos Family Vacation 3 BR. Centrally located and Ocean View

8. Suite with spectacular ocean view, you will wake up to the sound of the sea.

Suite with spectacular ocean view, you will wake up to the sound of the sea.
Puerto Ayora
8.0 out of 10, Very good, (1 review)
The price is €141
17 Oct - 18 Oct
Suite with spectacular ocean view, you will wake up to the sound of the sea.

9. Island Life Two-Bedroom Galapagos Casita

Island Life Two-Bedroom Galapagos Casita
Puerto Ayora
10.0 out of 10, Exceptional, (4 reviews)
"The host John was absolutely the BEST. He went above and beyond to make our stay wonderful. The house had everything one would need. "
United States
Trevor K.
The price is €180
13 Oct - 14 Oct
Island Life Two-Bedroom Galapagos Casita

10. Villa Galapagos

Villa Galapagos
2.5 star property
Puerto Ayora
6.0 out of 10, (1 review)
"着いて早々にダブルブッキングがわかった。これは施設というよりも、貴社のシステムの問題。前回も宿泊名簿に名前がなかったこともあり、強く改善をもとめる。"
Japan
アオアシカツオドリ
The price is €86
12 Oct - 13 Oct
Villa Galapagos

11. Galapagos Coliving Ecuador Casa Tuna

Galapagos Coliving Ecuador Casa Tuna
3.0 star property
Puerto Ayora
2.0 out of 10, (1 review)
"Beware of this scam, the owner did not receive our reservstion nor the money!"
United States
Maya
The price is €151
12 Oct - 13 Oct
Galapagos Coliving Ecuador Casa Tuna

12. 2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora
Puerto Ayora
The price is €83
15 Oct - 16 Oct
2-bedroom apartment with AC, WiFi in fabulous Puerto Ayora

13. TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"We enjoyed our 6-night stay at Ariana's. The apartment was large and comfortable. Bedroom air conditioners were whisper quiet. We especially enjoyed the rooftop terrace with its soft breezes. It’s a 20 minute walk to the big tortoise statue and a few minutes more to the Mlecon, or a 2 taxi ride."
Canada
Dean P.
The price is €93
12 Oct - 13 Oct
TWO Bedrooms Apartment ON THE Ground Floor IN Ariana`s Galapagos Hostal

14. Comfortable and cozy Galarous Island Suite

Comfortable and cozy Galarous Island Suite
Puerto Ayora
The price is €98
12 Oct - 13 Oct
Comfortable and cozy Galarous Island Suite

15. FAMILY SUITE in Puerto Ayora

FAMILY SUITE in Puerto Ayora
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Great lodging with effective space for multiple groups of travelers. Location is perfect, off the tourist path, and easy to access by any taxis in Puerto Arroyo (just say you want to go to Parque Cascada). Groceries are available anywhere near the house, better produce quality found in the shops on Baltra Ave. Property manager is easy to communicate with and responds instantly."
United States
Nathan M.
The price is €201
12 Oct - 13 Oct
FAMILY SUITE in Puerto Ayora

16. Comfortable Suite on Galarous Island

Comfortable Suite on Galarous Island
Puerto Ayora
The price is €156
12 Oct - 13 Oct
Comfortable Suite on Galarous Island

17. Island life Duplex great for groups

Island life Duplex great for groups
Puerto Ayora, Santa Cruz Island
Island life Duplex great for groups

18. Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi
Puerto Ayora
The price is €95
12 Oct - 13 Oct
Cozy 2-bedroom apartment in charming Puerto Ayora with AC, WiFi

19. Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC
Puerto Ayora
10.0 out of 10, Exceptional, (1 review)
"Stay was great and I really enjoy Daniel’s helpful service— can’t wait to come back and stay again!"
United States
Will L.
The price is €125
12 Oct - 13 Oct
Spacious 6-bedroom building in superb Puerto Ayora with AC and no AC

20. TWO Bedrooms Apartment ON THE First Floor Forest View

TWO Bedrooms Apartment ON THE First Floor Forest View
Puerto Ayora
The price is €93
12 Oct - 13 Oct
TWO Bedrooms Apartment ON THE First Floor Forest View
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santa Cruz Hotel Reviews

Find out more about Santa Cruz

Holiday Homes in Santa Cruz

Search for holiday homes in Santa Cruz on Expedia.ie! You can easily find your home rentals, villas, holiday apartments in Santa Cruz using one of the methods below: 

  • View our selection of featured holiday homes in Santa Cruz
  • Use the map to find apartments and other holiday rentals in the Santa Cruz neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday homes in Santa Cruz while they last

Look no further and take a look at our great range of rental properties in Santa Cruz!