A mountainous landscape with green valleys, rocky outcrops, and scattered buildings.

Cheap flights to Santa Isabel

View €77 flight on Thu, 24 Sept 2026Opens in a new window

Popular airlines to Santa Isabel

  • LATAM Airlines Group

  • Avianca

  • Aeromexico

  • Delta

  • Iberia

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Cheap round-trip flights to Santa Isabel

Prices were available within the past 7 days and start at €77 for one-way flights and €148 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
LATAM Airlines Group
avianca
LATAM Airlines Group
avianca
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group
LATAM Airlines Group

Frequently asked questions

How do I find cheap flights to Santa Isabel that have flexible change policies?
At Expedia, we've been channeling our inner Olympic gymnast to provide you with the most flexible fares on the market. Simply click on "No change fee" directly underneath the "Flexible change policies" subheading to find your ideal flight to Santa Isabel.
How can I find cheap tickets to Santa Isabel?
You'll always nab an awesome deal with Expedia, but our "flexible dates" search function makes it even easier. Enter your preferred flight date, then check the flexible dates box above to compare prices for nearby days. €148 was the cheapest price for a flight to Santa Isabel in the last seven days.
How much is a flight to Santa Isabel?
In the last seven days, return flights to Santa Isabel sold for as low as €148 and peaked at €171. For one-way journeys departing from Guayaquil (GYE), the cheapest seat during this time was only €77.
How much is a plane ticket to Santa Isabel?
Fares to Santa Isabel ranged from €148 to €171 in the last seven days. Usually, the sooner you make a reservation, the bigger the bargain.
What months are the cheapest to book a flight to Santa Isabel?
February is the most affordable month to book a seat for your Santa Isabel trip. Tickets cost the most during December, so keep clear of this time if possible.

Book with confidence

About Santa Isabel

Expedia offers flights to Santa Isabel to meet every traveller's needs. Whatever your flight need - Expedia has the flight for you. So choose from flights to Santa Isabel or destinations around the world and discover how easy it is to make your flight reservations on Expedia.
About Santa Isabel
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