A bridge over a calm river with a sunset sky.

Holiday Rentals in St. Charles County

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Our top choices for St. Charles County holiday rentals

Pool

Pool & Gym. Your Next Trip!

Pool & Gym. Your Next Trip!
O'Fallon
10.0 out of 10, Exceptional, (1 review)
"It was a fine short stay. Good breakfast!!"
United States
Elizabeth B.
Pool & Gym. Your Next Trip!
TV, fireplace

The Blake Cottage Wine Country Home

The Blake Cottage Wine Country Home
Augusta
8.4 out of 10, Very good, (11 reviews)
"It was a wonderful location for our girls' night! Plenty of room for our group and within walking distance of the wineries. "
United States
Deana T.
The price is €341
includes taxes & fees
28 Jun - 29 Jun
The Blake Cottage Wine Country Home
Living area

Cozy and Modern Augusta Hideaway Near Wineries and Katy Trail

Cozy and Modern Augusta Hideaway Near Wineries and Katy Trail
Augusta
9.8 out of 10, Exceptional, (39 reviews)
"Very nice place"
United States
Abraham
The price is €331
includes taxes & fees
2 Jul - 3 Jul
Cozy and Modern Augusta Hideaway Near Wineries and Katy Trail
Exterior

Rustic Augusta Wood Cabin

Rustic Augusta Wood Cabin
Augusta
9.6 out of 10, Exceptional, (8 reviews)
"I booked this place wit spend some homely time with my kids and it was amazing, the place was clean they even dropped off some extra towels without us having to ask, it was truly amazing. Will definitely stay there again. "
United States
teresa s.
The price is €312
includes taxes & fees
9 Jul - 10 Jul
Rustic Augusta Wood Cabin
Terrace/patio

WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL

WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL
Augusta
10.0 out of 10, Exceptional, (34 reviews)
"Comfortable place to stay. We appreciated the snacks and that there is a pack n play!"
United States
Samantha E.
The price is €259
includes taxes & fees
28 Jun - 29 Jun
WELCOME TO THE OWL'S NEST - 2 BEDROOM HOME IN AUGUSTA, WINERIES & THE KATY TRAIL
Interior

Adorable Augusta Cabin

Adorable Augusta Cabin
Augusta
8.4 out of 10, Very good, (18 reviews)
"Great little Cabin exactly as described. Weekend getaway with the wife clean and cozy. Would stay again if visiting the wineries "
United States
Michael W.
The price is €192
includes taxes & fees
28 Jun - 29 Jun
Adorable Augusta Cabin
Smart TV, fireplace, computer monitors

Charming open 4bd and screen-in porch! Sleeps 10!

Charming open 4bd and screen-in porch! Sleeps 10!
Saint Charles
9.2 out of 10, Wonderful, (44 reviews)
"Everything about the property was great. Very roomy and felt like home. "
United States
Dan R.
The price is €527
includes taxes & fees
28 Jun - 29 Jun
Charming open 4bd and screen-in porch! Sleeps 10!
Interior

The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (175 reviews)
"Great place to stay. Our go to when visiting St.Charles or STL"
United States
jeramy p.
The price is €230
includes taxes & fees
29 Jun - 30 Jun
The Lofts of North Main Street
Fridge, microwave, oven, stovetop

St. Charles Manor | 2BR Hot Tub Chalet | 1.2 Acres

St. Charles Manor | 2BR Hot Tub Chalet | 1.2 Acres
Saint Charles
8.8 out of 10, Excellent, (3 reviews)
"We loved the location for our travel needs and we had everything we needed for a family of two adults and two dogs. "
United States
Leslie R.
The price is €495
includes taxes & fees
28 Jun - 29 Jun
St. Charles Manor | 2BR Hot Tub Chalet | 1.2 Acres
1 bedroom, WiFi, bed sheets

Duplex Hideaway in St. Charles, MO

Duplex Hideaway in St. Charles, MO
St. Charles Historic District
9.8 out of 10, Exceptional, (6 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
The price is €223
includes taxes & fees
28 Jun - 29 Jun
Duplex Hideaway in St. Charles, MO
Smart TV, stereo

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
St. Charles Historic District
9.6 out of 10, Exceptional, (79 reviews)
"Great location and beautiful place. Had a wonderful time. "
United States
Ernest R.
The price is €226
includes taxes & fees
27 Jul - 28 Jul
Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
2 bedrooms, desk, iron/ironing board, free WiFi

Spacious Townhome Retreat

Spacious Townhome Retreat
O Fallon
10.0 out of 10, Exceptional, (11 reviews)
"Great quiet neighborhood close to everything!"
United States
Jen D.
The price is €413
includes taxes & fees
2 Jul - 3 Jul
Spacious Townhome Retreat
Dining

Cozy 3 Bedroom/ Family Comfort & Convenient Location

Cozy 3 Bedroom/ Family Comfort & Convenient Location
Wentzville
10.0 out of 10, Exceptional, (6 reviews)
"We had a wonderful stay! The home was very clean, check-in was super easy, and it was the perfect place for our family. Everything was exactly as described and we felt comfortable the entire time. Would definitely stay here again!"
United States
Tricia W.
The price is €317
includes taxes & fees
29 Jun - 30 Jun
Cozy 3 Bedroom/ Family Comfort & Convenient Location
A heated pool

Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
Great for Business Travelers! Pool + Gym
Private kitchen

Centrally located, spacious 4 bdrm, on quiet Ct

Centrally located, spacious 4 bdrm, on quiet Ct
O'Fallon
10.0 out of 10, Exceptional, (24 reviews)
"Lots of sleeping room and clean. Very conveniently located; close to interstate 70 which appears to be the main interstate throughout the St Louis area."
United States
Joan P.
Centrally located, spacious 4 bdrm, on quiet Ct
Exterior

HotTub-2br2b-near Historic Main Street

HotTub-2br2b-near Historic Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (8 reviews)
"Questions were answered quickly and the home was very welcoming. "
United States
T M.
The price is €306
includes taxes & fees
7 Jul - 8 Jul
HotTub-2br2b-near Historic Main Street
Interior

Cottage on Main st- Low Cleaning Fee

Cottage on Main st- Low Cleaning Fee
St. Charles Historic District
10.0 out of 10, Exceptional, (8 reviews)
"Good location. Decorated very nicely. "
United States
Debbie A.
The price is €266
includes taxes & fees
29 Jun - 30 Jun
Cottage on Main st- Low Cleaning Fee
TV

Main Street Apartment

Main Street Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (38 reviews)
"Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. "
United States
Brooke I.
The price is €365
includes taxes & fees
28 Jun - 29 Jun
Main Street Apartment
5 bedrooms, WiFi, bed sheets

Dog-Friendly 5-BR Home for Groups

Dog-Friendly 5-BR Home for Groups
Wentzville
10.0 out of 10, Exceptional, (11 reviews)
"Great place, great host"
United States
Elena R.
Dog-Friendly 5-BR Home for Groups
Interior

2 Bedroom Townhome Walking Distance to Streets

2 Bedroom Townhome Walking Distance to Streets
Saint Charles
9.0 out of 10, Wonderful, (19 reviews)
"We were located in a nice community and very close to the "The Streets" entertainment area (2 min away), Old town St. Charles (6 min away) and 15 minutes from the airport. The owner was very helpful and answered all my questions. Check this place out!"
United States
William D.
2 Bedroom Townhome Walking Distance to Streets
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top St. Charles County Hotel Reviews

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

8/10 Good
"I liked the hotel the pool was cool. Just the parking was a little annoying."
Megan 1-night trip
Posted 1 hour ago
Clayton Plaza Hotel & Extended Stay

Find out more about St. Charles County

Holiday Homes in St. Charles County

Search for holiday homes in St. Charles County on Expedia.ie! You can easily find your home rentals, villas, holiday apartments in St. Charles County using one of the methods below: 

  • View our selection of featured holiday homes in St. Charles County
  • Use the map to find apartments and other holiday rentals in the St. Charles County neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday homes in St. Charles County while they last

Look no further and take a look at our great range of rental properties in St. Charles County!