Spartanburg Hotel Guide - East Main Centre hotels in Spartanburg, United States of America.

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31 Dec - 1 Jan
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1 Jan - 2 Jan
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2 Jan - 4 Jan
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9 Jan - 11 Jan

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Our top choices for East Main Centre hotels

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AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg
3.5 star property
5.4 km from East Main Centre
9.2 out of 10, Wonderful, (587)
"The gentleman at the front desk when I checked in made me feel very comfortable. He was so chill. It was a great stay"
United States
robert
The price is €131
includes taxes & fees
1 Jan - 2 Jan 2026
AC Hotel by Marriott Spartanburg
Coffee shop
Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg
3.0 star property
10.7 km from East Main Centre
9.4 out of 10, Exceptional, (439)
"Friendly staff, clean rooms, excellent food! "
United States
Ashley
The price is €112
includes taxes & fees
1 Jan - 2 Jan 2026
Four Points by Sheraton Spartanburg
Terrace/patio
Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg
3.0 star property
11 km from East Main Centre
9.4 out of 10, Exceptional, (493)
"Staff was wonderful "
United States
Denise
The price is €111
includes taxes & fees
25 Jan - 26 Jan 2026
Hilton Garden Inn Spartanburg
Property amenity
Residence Inn by Marriott Spartanburg Westgate

Residence Inn by Marriott Spartanburg Westgate

Residence Inn by Marriott Spartanburg Westgate
3.0 star property
11.1 km from East Main Centre
9.4 out of 10, Exceptional, (214)
"Great hotel!"
United States
LeAnn
The price is €131
includes taxes & fees
1 Jan - 2 Jan 2026
Residence Inn by Marriott Spartanburg Westgate
Free daily buffet breakfast
Hampton Inn Spartanburg-North I-85

Hampton Inn Spartanburg-North I-85

Hampton Inn Spartanburg-North I-85
2.5 star property
5.6 km from East Main Centre
8.8 out of 10, Excellent, (1000)
"Good hotel "
United States
Yevgeniy
The price is €73
includes taxes & fees
9 Jan - 10 Jan 2026
Hampton Inn Spartanburg-North I-85
Reception
Tru by Hilton Spartanburg

Tru by Hilton Spartanburg

Tru by Hilton Spartanburg
2.5 star property
11.6 km from East Main Centre
9.2 out of 10, Wonderful, (832)
"Excellent hotel."
United States
Jairo
The price is €104
includes taxes & fees
6 Jan - 7 Jan 2026
Tru by Hilton Spartanburg
Lobby
Spartanburg Marriott

Spartanburg Marriott

Spartanburg Marriott
3.5 star property
5 km from East Main Centre
8.6 out of 10, Excellent, (1001)
"Clean, very kind and helpful staff, we had a wonderful and comfortable stay. "
United States
Courtney
The price is €136
includes taxes & fees
2 Jan - 3 Jan 2026
Spartanburg Marriott
Free buffet breakfast
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
2.5 star property
5.5 km from East Main Centre
8.6 out of 10, Excellent, (866)
"Yes, staff was great. The room was very clean."
United States
Angela
The price is €95
includes taxes & fees
25 Jan - 26 Jan 2026
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Free daily buffet breakfast
Best Western Plus Spartanburg

Best Western Plus Spartanburg

Best Western Plus Spartanburg
2.5 star property
7.9 km from East Main Centre
8.4 out of 10, Very good, (1000)
"Food was great! Rooms was good!"
United States
Audrey
The price is €84
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus Spartanburg
Lobby
Best Western Spartanburg Northwest

Best Western Spartanburg Northwest

Best Western Spartanburg Northwest
3.0 star property
8.1 km from East Main Centre
8.2 out of 10, Very good, (824)
"Great place"
United States
Jamie
The price is €87
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Spartanburg Northwest
Free daily full breakfast
Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall
2.5 star property
10.5 km from East Main Centre
8.2 out of 10, Very good, (1000)
"The room was great."
United States
Lacy
The price is €88
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Suites At WestGate Mall
Lobby
ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg

ECHO Suites Extended Stay by Wyndham Spartanburg
2.0 star property
10.6 km from East Main Centre
8.2 out of 10, Very good, (309)
"Nice hotel "
United States
Kierra
The price is €69
includes taxes & fees
4 Jan - 5 Jan 2026
ECHO Suites Extended Stay by Wyndham Spartanburg
Exterior
Comfort Inn & Suites Spartanburg North

Comfort Inn & Suites Spartanburg North

Comfort Inn & Suites Spartanburg North
2.5 star property
8.2 km from East Main Centre
7.8 out of 10, Good, (972)
"Very comfortable beds quiet clean room they weren’t skimpy with towels or other supplies and really put a lot into their Christmas tree - not the bare minimum like most places these days and location for traveling is perfect! We stayed here twice & plan to again! Also the price was very reasonable!"
United States
Sue
The price is €81
includes taxes & fees
5 Jan - 6 Jan 2026
Comfort Inn & Suites Spartanburg North
Property amenity
Residence Inn by Marriott Spartanburg

Residence Inn by Marriott Spartanburg

Residence Inn by Marriott Spartanburg
3.0 star property
10.7 km from East Main Centre
8.0 out of 10, Very good, (462)
"The location was quiet and the staff were very friendly."
United States
Andrew
The price is €94
includes taxes & fees
8 Jan - 9 Jan 2026
Residence Inn by Marriott Spartanburg
Free daily buffet breakfast
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
2.5 star property
11 km from East Main Centre
8.6 out of 10, Excellent, (985)
"Room was spotless, staff was very friendly. "
United States
Anne-Marie
The price is €104
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
Restaurant
Holiday Inn Spartanburg Northwest by IHG

Holiday Inn Spartanburg Northwest by IHG

Holiday Inn Spartanburg Northwest by IHG
2.5 star property
8.3 km from East Main Centre
7.6 out of 10, Good, (832)
"Breakfast was not free but our stay was enjoyable overall. Clean and convenient location for my work trip and staff was really friendly "
United States
Jennifer
The price is €99
includes taxes & fees
2 Jan - 3 Jan 2026
Holiday Inn Spartanburg Northwest by IHG
Exterior
USA Economy Lodge

USA Economy Lodge

USA Economy Lodge
2.0 star property
8.5 km from East Main Centre
7.6 out of 10, Good, (85)
"Loved it very quiet and pleasant "
United States
Tameesha
USA Economy Lodge
Free daily on-the-go breakfast
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
2.5 star property
10.7 km from East Main Centre
8.8 out of 10, Excellent, (713)
"Room was excellent- clean. Breakfast was ok- wished for different meat to choose from "
United States
pearl
The price is €84
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
Outdoor pool
Days Inn by Wyndham Spartanburg

Days Inn by Wyndham Spartanburg

Days Inn by Wyndham Spartanburg
2.0 star property
9 km from East Main Centre
7.6 out of 10, Good, (146)
"This hotel was okay"
United States
Shannon
The price is €73
includes taxes & fees
4 Jan - 5 Jan 2026
Days Inn by Wyndham Spartanburg
Desk, laptop workspace, blackout curtains, free WiFi
Motel 6 Spartanburg, Sc – Northwest / Business 85

Motel 6 Spartanburg, Sc – Northwest / Business 85

Motel 6 Spartanburg, Sc – Northwest / Business 85
2.0 star property
6.1 km from East Main Centre
7.2 out of 10, Good, (73)
"Old building. Not well kept. Piles of dog poop everywhere. Holes in the sheets. It was basic shelter. "
United States
Roger
The price is €73
includes taxes & fees
1 Jan - 2 Jan 2026
Motel 6 Spartanburg, Sc – Northwest / Business 85
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top East Main Centre Hotel Reviews

Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg

10/10 Excellent
"The room was clean and staff was nice but the breakfast was not free as suggested above on the survey. I was charged for my breakfast. "
Katina 1-night trip
Posted 2 days ago
Four Points by Sheraton Spartanburg

Hotels near other East Main Centre attractions

Eastpointe Shopping Center

You can find the perfect gifts to bring home at Eastpointe Shopping Center during your stay in Spartanburg. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Hillcrest Shopping Center

You can do some window-shopping at Hillcrest Shopping Center during your trip to Spartanburg. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around East Main Centre?
East Main Centre is located in Spartanburg. This family-friendly area is known for its array of dining options and sporting events. You'll find 94 hotels and other accommodations within a few miles for a convenient home base.
Where is the best place to stay close to East Main Centre?
Spartanburg Marriott is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and free parking. It's located 3.1 mi (5 km) from East Main Centre. Another good choice is Hampton Inn Spartanburg-North I-85, located 3.5 mi (5.6 km) away.
How many hotels will I find close to East Main Centre?
Expedia has 94 hotels and other accommodation options a few miles from East Main Centre.
If I need to cancel the hotel reservation for my stay near East Main Centre, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to get the best deals near East Main Centre.
What can I see and do near East Main Centre?
You'll want to browse the exhibits at Hub City Railroad Museum and Spartanburg Regional History Museum. Sights like Spartanburg Memorial Auditorium and Spartanburg Regional Hospital highlight some of the local culture. You can check out the local talent at Twitchell Auditorium, Chapman Cultural Center and Rainey Amphitheater.