A calm lake surrounded by trees with autumn foliage.

Florence Hotel Guide - Hotels in Florence Regional, Florence, United States of America

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Check prices for these dates

Next weekend
30 Oct - 1 Nov
In two weeks
6 Nov - 8 Nov

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Our top choices for Florence, SC (FLO-Florence Regional) hotels

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

1. Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence
2.0 star property
8 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (2,752 reviews)
"A convenient stop for travelers to rest."
United States
Alanda
The price is €61
includes taxes & fees
25 Oct - 26 Oct
Howard Johnson by Wyndham Florence
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

2. Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC
2.5 star property
8 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (2,480 reviews)
"Would stay here again - convenient and comfortable"
United States
Amy
The price is €90
includes taxes & fees
1 Nov - 2 Nov
Park Inn by Radisson Florence, SC
A hotel lobby with a reception desk, seating area, and a television screen.

3. Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area
2.5 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,375 reviews)
"Breakfast was excellent. Room was clean and quiet."
United States
Mila
The price is €101
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites Florence Center Area
A hotel room with two beds, a television, a desk, and a framed picture on the wall.

4. Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95
2.5 star property
8.2 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (998 reviews)
"Great location and great rooms. We were definitely pleased with our stay."
United States
Ladavish
The price is €122
includes taxes & fees
1 Nov - 2 Nov
Hampton Inn & Suites Florence-North-I-95
A swimming pool with lounge chairs and a view of the outdoors.

5. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
2.5 star property
8.3 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1,002 reviews)
"Good location- very good free breakfast"
United States
Christopher
The price is €131
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

6. La Quinta Inn & Suites by Wyndham Florence

La Quinta Inn & Suites by Wyndham Florence
3.0 star property
8.1 km from Florence, SC (FLO-Florence Regional)
7.8 out of 10, Good, (1,462 reviews)
"Close to the restaurants and shopping."
United States
Brenda
The price is €86
includes taxes & fees
25 Oct - 26 Oct
La Quinta Inn & Suites by Wyndham Florence
A hotel room with a desk, chair, bed, and a yellow sofa.

7. Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center
2.5 star property
10.2 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (407 reviews)
"Nice spot for an overnight!"
United States
Sharhonda
The price is €89
includes taxes & fees
1 Nov - 2 Nov
Quality Inn & Suites Florence Civic Center
A spacious lobby with a reception desk, seating area, and large windows.

8. Hilton Garden Inn Florence

Hilton Garden Inn Florence
2.5 star property
9.9 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (357 reviews)
"Rooms were clean and staff was friendly."
United States
Derrick
The price is €118
includes taxes & fees
1 Nov - 2 Nov
Hilton Garden Inn Florence
A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

9. TownePlace Suites by Marriott Florence

TownePlace Suites by Marriott Florence
3.0 star property
9.7 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (919 reviews)
"The staff was amazing!!! The rooms are impeccable the kitchen is excellent!!! I would love to stay here every time"
United States
Crystal
The price is €110
includes taxes & fees
1 Nov - 2 Nov
TownePlace Suites by Marriott Florence
A multi-story hotel with a prominent entrance and signage for Springhill Suites by Marriott.

10. SpringHill Suites by Marriott Florence

SpringHill Suites by Marriott Florence
3.0 star property
9.8 km from Florence, SC (FLO-Florence Regional)
8.2 out of 10, Very good, (1,003 reviews)
"The room Was clean and comfortable and the breakfast was good."
United States
John
The price is €107
includes taxes & fees
26 Oct - 27 Oct
SpringHill Suites by Marriott Florence
A fire pit surrounded by chairs and tables, with a staircase leading to an entrance, and a large window with a curtain.

11. Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG
3.0 star property
10.7 km from Florence, SC (FLO-Florence Regional)
9.4 out of 10, Exceptional, (1,003 reviews)
"Enjoyed our stay."
United States
Tishia
The price is €131
includes taxes & fees
15 Nov - 16 Nov
Staybridge Suites Florence - Civic Center by IHG
A hotel entrance with a stone facade, glass doors, and a number '501' above.

12. Fairfield Inn & Suites by Marriott Florence I-20

Fairfield Inn & Suites by Marriott Florence I-20
3.0 star property
9.6 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (662 reviews)
"I enjoyed a two night stay here at Fairfield. The staff was completely awesome. The breakfast was amazing, so many options to choose from to meet every healthy meal plan. The amenities were very clean, modern and chic, providing an upscale experience. Overall experience was excellent!"
United States
Alma
The price is €118
includes taxes & fees
1 Nov - 2 Nov
Fairfield Inn & Suites by Marriott Florence I-20
A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

13. Residence Inn Marriott Florence

Residence Inn Marriott Florence
3.0 star property
9.9 km from Florence, SC (FLO-Florence Regional)
8.8 out of 10, Excellent, (585 reviews)
"The room was clean and spacious. The staff was friendly."
United States
Teri
The price is €107
includes taxes & fees
1 Nov - 2 Nov
Residence Inn Marriott Florence
A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

14. Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center
2.5 star property
9.9 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (992 reviews)
"Very enjoyable stay"
United States
William
The price is €93
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn & Suites Florence Center
A Holiday Inn Express & Suites hotel with a covered entrance, palm trees, and a clear sky.

15. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
2.5 star property
10.7 km from Florence, SC (FLO-Florence Regional)
9.0 out of 10, Wonderful, (1,001 reviews)
"Wonderful hotel and in a great location!"
United States
Leigh
The price is €107
includes taxes & fees
22 Nov - 23 Nov
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG
A hotel with a modern design, multiple floors, and a parking lot.

16. Best Western Inn

Best Western Inn
2.5 star property
7.2 km from Florence, SC (FLO-Florence Regional)
7.8 out of 10, Good, (1,000 reviews)
"Clean rooms and friendly staff and great breakfast"
United States
Steward Heikes
The price is €89
includes taxes & fees
25 Oct - 26 Oct
Best Western Inn
A swimming pool with lounge chairs and a building with a sign reading "BAYMONT".

17. Super 8 by Wyndham Florence

Super 8 by Wyndham Florence
2.0 star property
7.3 km from Florence, SC (FLO-Florence Regional)
7.2 out of 10, Good, (1,007 reviews)
"Great and affordable stay"
United States
Shawn
The price is €54
includes taxes & fees
26 Oct - 27 Oct
Super 8 by Wyndham Florence
A hotel room with two beds, a wooden headboard, a nightstand, and three sunset paintings on the wall.

18. Days Inn by Wyndham Florence Near Civic Center

Days Inn by Wyndham Florence Near Civic Center
2.5 star property
10.2 km from Florence, SC (FLO-Florence Regional)
7.4 out of 10, Good, (1,002 reviews)
"Good rooms for the price"
United States
Louis
The price is €69
includes taxes & fees
25 Oct - 26 Oct
Days Inn by Wyndham Florence Near Civic Center
A modern hotel with a covered entrance, large windows, and a sign indicating it is a hotel.

19. Aloft by Marriott Florence

Aloft by Marriott Florence
3.0 star property
10.2 km from Florence, SC (FLO-Florence Regional)
8.4 out of 10, Very good, (393 reviews)
"Excellent stay"
United States
Darlene
The price is €117
includes taxes & fees
29 Oct - 30 Oct
Aloft by Marriott Florence
An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

20. Tru by Hilton Florence I-95

Tru by Hilton Florence I-95
2.5 star property
8.4 km from Florence, SC (FLO-Florence Regional)
8.6 out of 10, Excellent, (1,002 reviews)
"Great hotel and staff"
United States
Margarita
The price is €96
includes taxes & fees
8 Nov - 9 Nov
Tru by Hilton Florence I-95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Florence, SC (FLO-Florence Regional)

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious lobby with a checkered floor, a reception desk, and a chandelier.
Howard Johnson by Wyndham Florence
2.0 star property
8.6
Excellent
2,752 reviews
View
A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.
Park Inn by Radisson Florence, SC
2.5 star property
9.0
Wonderful
2,480 reviews
View
A hotel lobby with a reception desk, seating area, and a television screen.
Comfort Inn & Suites Florence Center Area
2.5 star property
9.0
Wonderful
1,375 reviews
View
A hotel room with two beds, a television, a desk, and a framed picture on the wall.
Hampton Inn & Suites Florence-North-I-95
2.5 star property
9.0
Wonderful
998 reviews
View
A swimming pool with lounge chairs and a view of the outdoors.
Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG
2.5 star property
8.6
Excellent
1,002 reviews
View

Top Florence Regional Hotel Reviews

Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

8/10 Good
"Clean good spot to rest. Would stay again."
Sarah 1-night trip
Posted 5 hours ago
Howard Johnson by Wyndham Florence

Guide to exploring Florence Regional

Florence Regional hotels information

Number of reviews
12,774
Accommodation
134 hotels
Lowest Price
€54
Highest Price
€131

Frequently asked questions

What's the area like near Florence, SC (FLO-Florence Regional)?

Florence, SC (FLO-Florence Regional) is located in a welcoming area of Florence known for its array of dining options. You'll find 72 hotels and other accommodations within a few miles of the airport for a convenient home base.

Where is the best place to stay close to Florence, SC (FLO-Florence Regional)?

Hyatt Place Florence Downtown is one of the top choices for your stay and is a popular hotel, featuring free breakfast and free WiFi. It's located 2.2 mi (3.5 km) from Florence, SC (FLO-Florence Regional). Other choices near the airport include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.

How many hotels can I expect to find close to Florence, SC (FLO-Florence Regional)?

Expedia has 72 hotels and other accommodation options a few miles from the airport.

What can I see and do near the airport in Florence?

Sights like Mcleod Regional Medical Center and Florence Stockade highlight some of the local culture. You can enjoy live performances at Florence Little Theatre and FMU Performing Arts Center. If you've got some time to explore the area around Florence, SC (FLO-Florence Regional), you may want to make a stop by Dr. Eddie Floyd Tennis Center, Southgate Bowling Center and CarolinaBank Field.