A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Florida Keys Hotel Guide - Hotels with Spa in Florida Keys, United States of America

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Check availability on Florida Keys Hotels with Spa

Tonight
22 Oct - 23 Oct
Tomorrow
23 Oct - 24 Oct
This weekend
23 Oct - 25 Oct
Next weekend
30 Oct - 1 Nov

Our top choices for Florida Keys hotels with a spa

A view through a window with metal bars, featuring a beach with palm trees, a thatched umbrella, and a wooden dock.
A beachside resort with lounge chairs, a pool, and palm trees.
A beach with kayaks lined up near the water's edge, palm trees, and lounge chairs.
A clear blue pool surrounded by palm trees and a thatched-roof structure, with a sign indicating no diving.

1. Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
Rock Harbor
  • Serene spa getaway with tranquil gardens and sunset views from the oceanfront hot tub.
€129
includes taxes & fees
25 Oct - 26 Oct
Kona Kai Resort and Gallery - Adults Only
A conference room with a large painting of a blue ocean, two Laptops, and wicker chairs.
A balcony with a view of palm trees and the sea, a white railing, and a table with chairs.
A tropical resort with a swimming pool, palm trees, and a waterfall.
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.

2. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
  • Luxury spa sanctuary with 7 treatment rooms offers beachside massages and tranquil gardens for ultimate rejuvenation.
€264
includes taxes & fees
19 Nov - 20 Nov
Cheeca Lodge & Spa
A modern, well-organized room with a white sofa, a white chair, a gold lamp, and a white bookshelf filled with various items.
A beach with white chairs and kayaks, palm trees, and a clear view of the ocean.
Room
An aerial view of a resort with a central pool, multiple buildings, and a beach area with sun loungers.

3. Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
Marathon
  • Restore serenity at this beachfront hotel with 5 tranquil spa treatment rooms and multiple outdoor pools overlooking stunning ocean views.
€260
includes taxes & fees
25 Oct - 26 Oct
Isla Bella Beach Resort & Spa
A room with a bed, a ceiling fan, and a view of the ocean.
A poolside area with lounge chairs and umbrellas, palm trees, and a view of the sea.
A beachfront hotel with multiple-story buildings, palm trees, and a sandy beach.
A room with a view of the beach and ocean, a bed with a white and blue blanket, and a small table with a potted plant.

4. Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
Old Town Key West
  • Serene beachside spa oasis offers tropical relaxation with ocean views and couples treatments.
€236
includes taxes & fees
25 Oct - 26 Oct
Southernmost Beach Resort and Guesthouses
A modern bathroom with a marble floor, a large mirror, and a wooden vanity.
A balcony with a view of the ocean, a sofa, and a massage table.
A beach with clear blue water, a sandy shore, and a distant bridge.
A resort with a beach, a dock, and a water view.

5. Pier House Resort & Spa

Pier House Resort & Spa
Key West Historic District
  • Waterfront spa resort invites relaxation with private beach, outdoor pool, and rejuvenating treatments in Key West's central locale.
€236
includes taxes & fees
26 Oct - 27 Oct
Pier House Resort & Spa
A hotel room with a bed, a dresser, a mirror, and a nightstand.
A beachfront property with a balcony overlooking the sea, palm trees, and a well-lit outdoor seating area.
A spacious bar area with high ceilings and large windows, offering views of the ocean.
A poolside area with blue chairs and a thatched-roof structure.

6. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
  • Discover tranquil bliss at this waterfront haven with three spa rooms, private beach, and hot stone massages.
€255
includes taxes & fees
25 Oct - 26 Oct
Reefhouse Resort & Marina
A massage therapy session in a room with a city view.
A beach with a wooden pier, palm trees, and beach umbrellas.
A resort with a pool, lounge chairs, umbrellas, palm trees, and a view of the ocean.
An outdoor dining area with tables set for guests, overlooking a calm sea and a pier.

7. The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
Old Town Key West
  • Luxurious beachfront spa retreat offers deep-tissue massages and serene outdoor treatments in Key West.
€239
includes taxes & fees
26 Oct - 27 Oct
The Reach Key West, Curio Collection by Hilton
Sports facility
Restaurant
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a large tree in the background.
A bar area with a long counter, multiple stools, and a view of the marina with boats.

8. Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
  • Rejuvenate at this waterfront resort's luxurious Ocean Spa with specialised massages in serene rooms.
€181
includes taxes & fees
8 Nov - 9 Nov
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
A modern hotel room with a circular white bed, a bathroom with a mirror and toiletries, and a shelf with OSEA products.
A hotel with a swimming pool, balconies, and a view of the sea.
A balcony with a table and chairs, overlooking a turquoise sea with boats and a distant shoreline.
A balcony with a view of the ocean, a table, chairs, and a railing.

9. Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
Key West Historic District
  • Luxurious oceanfront escape with 3 spa treatment rooms offers deep-tissue massages, facials, and holistic therapies for pure rejuvenation.
€300
includes taxes & fees
25 Oct - 26 Oct
Hyatt Centric Key West Resort and Spa
Lobby
A large resort building with multiple balconies, palm trees, and a well-lit entrance area.
A waterfront hotel with multiple balconies, a dock, and boats.
A covered balcony with white Adirondack chairs and a small table with flowers, overlooking a turquoise sea and distant shoreline.

10. Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
Old Town Key West
  • Indulge in oceanfront spa retreats with sunset views at this tropical Key West haven just steps from Duval Street.
€295
includes taxes & fees
25 Oct - 26 Oct
Opal Key Resort & Marina, Key West
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Choose what matters most at spa hotels in Florida Keys

Pool
Breakfast included
Hot tub
4 stars
5 stars

Spa hotels with pools in Florida Keys

A beach with a wooden pier, palm trees, and beach umbrellas.
A resort with a pool, lounge chairs, umbrellas, palm trees, and a view of the ocean.
An outdoor dining area with tables and chairs, overlooking the ocean.
A modern bar area with a central island, white bar stools, and a view of the ocean.

The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
Old Town Key West
€239
includes taxes & fees
26 Oct - 27 Oct
The Reach Key West, Curio Collection by Hilton
A deck with sun loungers and a railing overlooking the sea.
A beachside hotel with rows of blue lounge chairs and white umbrellas, palm trees, and a clear blue sky.
A beach scene with two people relaxing under a white umbrella, a palm tree, and a clear blue sky.
A room with a view of the beach and ocean, a bed with a white and blue blanket, and a small table with a potted plant.

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
Old Town Key West
€236
includes taxes & fees
25 Oct - 26 Oct
Southernmost Beach Resort and Guesthouses
A bathroom with a large bathtub, a view of the sea, and a pier with boats.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A hotel room with a large bed, a television, a dining area with chairs, a table, and a view of the ocean.
A tropical resort with a swimming pool, palm trees, and a waterfall.

Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
€264
includes taxes & fees
19 Nov - 20 Nov
Cheeca Lodge & Spa
An aerial view of a resort with a central pool, multiple buildings, and a beach area with sun loungers.
An aerial view of a resort with a large building, a beach, and a pier in the background.
A bar area with wooden chairs, a bar counter, and a variety of bottles and glasses.
A beach scene with two white chairs, a hammock, and palm trees.

Isla Bella Beach Resort & Spa

Isla Bella Beach Resort & Spa
Marathon
€260
includes taxes & fees
25 Oct - 26 Oct
Isla Bella Beach Resort & Spa
A wooden deck with wicker furniture and a glass balustrade overlooking a beach.
A spacious lobby with green sofas, a coffee table, and a dining area.
A beach with white lounge chairs and umbrellas, a sandy shore, and a calm sea under a partly cloudy sky.
A resort with a pool leading to a beach, surrounded by palm trees and white buildings.

Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
Old Town Key West
€306
includes taxes & fees
1 Nov - 2 Nov
Casa Marina Key West, Curio Collection by Hilton
A hotel with a swimming pool, balconies, and a view of the sea.
A balcony with a view of the ocean, a table, chairs, and a railing.
A beach wedding setup with white chairs, a wooden arch, and lanterns.
A marina with jet skis docked in front of a hotel with a dock and a boat in the background.

Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
Key West Historic District
€300
includes taxes & fees
25 Oct - 26 Oct
Hyatt Centric Key West Resort and Spa
A beachfront hotel with a covered patio, palm trees, and a boat on the sand.
A view through a white-framed window with a decorative white fence, leading to a tiled patio area with a round table.
A balcony with a view of the ocean, a sofa, and a massage table.
A resort with a beach, a dock, and a water view.

Pier House Resort & Spa

Pier House Resort & Spa
Key West Historic District
€236
includes taxes & fees
26 Oct - 27 Oct
Pier House Resort & Spa
A hotel with a covered entrance, multiple balconies, and palm trees.
A restaurant interior with wooden beams, a bar area, and a colorful ceiling mural.
A waterfront hotel with multiple balconies, a dock, and boats.
A covered balcony with white Adirondack chairs and a small table with flowers, overlooking a turquoise sea and distant shoreline.

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
Old Town Key West
€295
includes taxes & fees
25 Oct - 26 Oct
Opal Key Resort & Marina, Key West
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a large tree in the background.
A modern hotel room with a sofa, a small table, a lamp, and a bed.
A fire pit with two Adirondack chairs and a table with drinks, set on a grassy area with a view of a building and palm trees in the background.
A bar area with a long counter, multiple stools, and a view of the marina with boats.

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
€181
includes taxes & fees
8 Nov - 9 Nov
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
A tropical resort with a clear pool, palm trees, and lounge chairs.
A view through a window with metal bars, featuring a beach with palm trees, a thatched umbrella, and a wooden dock.
A clear blue pool surrounded by palm trees and a thatched-roof structure, with a sign indicating no diving.
A tropical resort with a paved pathway leading to a building, surrounded by palm trees and lush greenery.

Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
Rock Harbor
€129
includes taxes & fees
25 Oct - 26 Oct
Kona Kai Resort and Gallery - Adults Only
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Spa hotels with free breakfast in Florida Keys

A beach with a wooden pier, palm trees, and beach umbrellas.
A resort with a pool, lounge chairs, umbrellas, palm trees, and a view of the ocean.
An outdoor dining area with tables and chairs, overlooking the ocean.
A modern bar area with a central island, white bar stools, and a view of the ocean.

The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
Old Town Key West
€239
includes taxes & fees
26 Oct - 27 Oct
The Reach Key West, Curio Collection by Hilton
A deck with sun loungers and a railing overlooking the sea.
A beachside hotel with rows of blue lounge chairs and white umbrellas, palm trees, and a clear blue sky.
A beach scene with two people relaxing under a white umbrella, a palm tree, and a clear blue sky.
A room with a view of the beach and ocean, a bed with a white and blue blanket, and a small table with a potted plant.

Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses
Old Town Key West
€236
includes taxes & fees
25 Oct - 26 Oct
Southernmost Beach Resort and Guesthouses
A wooden deck with wicker furniture and a glass balustrade overlooking a beach.
A spacious lobby with green sofas, a coffee table, and a dining area.
A beach with white lounge chairs and umbrellas, a sandy shore, and a calm sea under a partly cloudy sky.
A resort with a pool leading to a beach, surrounded by palm trees and white buildings.

Casa Marina Key West, Curio Collection by Hilton

Casa Marina Key West, Curio Collection by Hilton
Old Town Key West
€306
includes taxes & fees
1 Nov - 2 Nov
Casa Marina Key West, Curio Collection by Hilton
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a large tree in the background.
A modern hotel room with a sofa, a small table, a lamp, and a bed.
A fire pit with two Adirondack chairs and a table with drinks, set on a grassy area with a view of a building and palm trees in the background.
A bar area with a long counter, multiple stools, and a view of the marina with boats.

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton

Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
Marathon
€181
includes taxes & fees
8 Nov - 9 Nov
Faro Blanco Resort Marathon Florida Keys, Curio by Hilton
A hotel with a swimming pool, balconies, and a view of the sea.
A balcony with a view of the ocean, a table, chairs, and a railing.
A beach wedding setup with white chairs, a wooden arch, and lanterns.
A marina with jet skis docked in front of a hotel with a dock and a boat in the background.

Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
Key West Historic District
€300
includes taxes & fees
25 Oct - 26 Oct
Hyatt Centric Key West Resort and Spa
A beachfront hotel with a covered patio, palm trees, and a boat on the sand.
A view through a white-framed window with a decorative white fence, leading to a tiled patio area with a round table.
A balcony with a view of the ocean, a sofa, and a massage table.
A resort with a beach, a dock, and a water view.

Pier House Resort & Spa

Pier House Resort & Spa
Key West Historic District
€236
includes taxes & fees
26 Oct - 27 Oct
Pier House Resort & Spa
An aerial view of a resort with a large pool, palm trees, and a beach.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.
A beachside patio with lounge chairs, a table, and a view of the ocean.
A beach with clear water, a wooden pier, and lounge chairs under a tree.

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
€353
includes taxes & fees
9 Nov - 10 Nov
Playa Largo Resort & Spa, Autograph Collection
A table with a glass pitcher, a glass with a slice of lime, and a plate with raspberries and a sprig of rosemary.
A child sitting on a beach with sand toys and a green bucket nearby.
An aerial view of a resort with two large swimming pools surrounded by palm trees and lounge chairs.
Restaurant

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
€306
includes taxes & fees
29 Oct - 30 Oct
Baker's Cay Resort Key Largo, Curio Collection by Hilton
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Spa hotels with hot tubs in Florida Keys

A bathroom with a large bathtub, a view of the sea, and a pier with boats.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A hotel room with a large bed, a television, a dining area with chairs, a table, and a view of the ocean.
A tropical resort with a swimming pool, palm trees, and a waterfall.

Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
€264
includes taxes & fees
19 Nov - 20 Nov
Cheeca Lodge & Spa
A tropical resort with a clear pool, palm trees, and lounge chairs.
A view through a window with metal bars, featuring a beach with palm trees, a thatched umbrella, and a wooden dock.
A clear blue pool surrounded by palm trees and a thatched-roof structure, with a sign indicating no diving.
A tropical resort with a paved pathway leading to a building, surrounded by palm trees and lush greenery.

Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
Rock Harbor
€129
includes taxes & fees
25 Oct - 26 Oct
Kona Kai Resort and Gallery - Adults Only
A beachfront hotel with a covered patio, palm trees, and a boat on the sand.
A view through a white-framed window with a decorative white fence, leading to a tiled patio area with a round table.
A balcony with a view of the ocean, a sofa, and a massage table.
A resort with a beach, a dock, and a water view.

Pier House Resort & Spa

Pier House Resort & Spa
Key West Historic District
€236
includes taxes & fees
26 Oct - 27 Oct
Pier House Resort & Spa
A hotel with a covered entrance, multiple balconies, and palm trees.
A restaurant interior with wooden beams, a bar area, and a colorful ceiling mural.
A waterfront hotel with multiple balconies, a dock, and boats.
A covered balcony with white Adirondack chairs and a small table with flowers, overlooking a turquoise sea and distant shoreline.

Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
Old Town Key West
€295
includes taxes & fees
25 Oct - 26 Oct
Opal Key Resort & Marina, Key West
A pool area with lounge chairs and umbrellas, surrounded by palm trees.
An aerial view of a coastal resort with multiple white buildings, a clear turquoise sea, and lush greenery.
A modern living room with a balcony overlooking the sea, furnished with a sofa, chairs, and a dining table.
A spacious lobby with high ceilings, large windows, and a central coffee table surrounded by sofas and chairs.

Hawks Cay Resort

Hawks Cay Resort
Marathon
€300
includes taxes & fees
15 Nov - 16 Nov
Hawks Cay Resort
A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A poolside area with blue chairs and a thatched-roof structure.
A spacious bar area with high ceilings and large windows, offering views of the ocean.
A spacious living room with large windows, comfortable seating, and decorative plants.

Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
€255
includes taxes & fees
25 Oct - 26 Oct
Reefhouse Resort & Marina
A table with a glass pitcher, a glass with a slice of lime, and a plate with raspberries and a sprig of rosemary.
A child sitting on a beach with sand toys and a green bucket nearby.
An aerial view of a resort with two large swimming pools surrounded by palm trees and lounge chairs.
Restaurant

Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton
Key Largo
€306
includes taxes & fees
29 Oct - 30 Oct
Baker's Cay Resort Key Largo, Curio Collection by Hilton
An aerial view of a resort with a large pool, palm trees, and a beach.
A restaurant with wooden tables and chairs, a bar area, and a view of the sea.
A beachside patio with lounge chairs, a table, and a view of the ocean.
A beach with clear water, a wooden pier, and lounge chairs under a tree.

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
Rock Harbor
€353
includes taxes & fees
9 Nov - 10 Nov
Playa Largo Resort & Spa, Autograph Collection
A balcony with a wooden table, two chairs, and a view of the ocean and palm trees.
A resort with multiple white buildings, each featuring balconies and surrounded by lush greenery and palm trees.
A pool area with clear blue water, white lounge chairs, and palm trees.
A gated entrance to a resort with palm trees and a clear sky.

The Islands of Islamorada

The Islands of Islamorada
Matecumbe
€581
includes taxes & fees
27 Oct - 28 Oct
The Islands of Islamorada
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Florida Keys Hotel Reviews

Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
""The view was absolutely amazing and the property was gorgeous. Everything about our stay was perfect—our only complaint was that the pool was cold and took the family a while to get used to. However, in defense of the property, we did visit in October! We will definitely be returning!""
Vanessa 3-night trip
Posted less than an hour ago
Reefhouse Resort & Marina
Amara Cay Resort

Amara Cay Resort

10/10 Excellent
"Excellent"
Yusnier 1-night trip
Posted 1 hour ago
Amara Cay Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"The hotel is expensive enough anyway without hidden extras Stealth tax what they’ve now labelled resort $50 a night tax plus $25 per night car parking Shame because it has a lovely vibe about the place"
Dean 1-night trip
Posted 1 day ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Hawks Cay Resort

Hawks Cay Resort

10/10 Excellent
"The place is very relaxing. Very clean. No bugs. Helpful polite staff. No complains at all. Just keep the fact that additional charges at check out are quite high."
Frederick 5-night trip
Posted 2 days ago
Hawks Cay Resort