Photo by Jen - Nealys On Wheels

Santa Fe Hotel Guide. Hotels in Guadalupe District, Santa Fe, United States of America

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Our top choices for Guadalupe District hotels

Porch
Guadalupe Inn

Guadalupe Inn

Guadalupe Inn
2.0 star property
Guadalupe District
9.2 out of 10, Wonderful, (1000)
"Cozy, quiet, and great for couples!"
United States
Emerson
The price is €100
includes taxes & fees
11 Jan - 12 Jan 2026
Guadalupe Inn
Terrace/patio
The Sage Hotel

The Sage Hotel

The Sage Hotel
3.0 star property
Don Diego, 0.6 km from Guadalupe District
8.0 out of 10, Very good, (2156)
"Very friendly staff, beautifully clean rooms, great parking, and safe environment."
United States
Tavares
The price is €70
includes taxes & fees
5 Jan - 6 Jan 2026
The Sage Hotel
Exterior
El Sendero Inn, an Ascend Collection Hotel

El Sendero Inn, an Ascend Collection Hotel

El Sendero Inn, an Ascend Collection Hotel
2.5 star property
Downtown Santa Fe, 1.2 km from Guadalupe District
9.0 out of 10, Wonderful, (1544)
"Great stay. Will stay there again. "
United States
Mark
The price is €88
includes taxes & fees
4 Jan - 5 Jan 2026
El Sendero Inn, an Ascend Collection Hotel
Standard Room, 2 Queen Beds (Double Queen Room)
Coyote South

Coyote South

Coyote South
3.5 star property
Southside, 6.3 km from Guadalupe District
8.4 out of 10, Very good, (3017)
"Great staff excellent accommodations "
United States
Randall
The price is €67
includes taxes & fees
4 Jan - 5 Jan 2026
Coyote South
Exterior
La Quinta Inn by Wyndham Santa Fe

La Quinta Inn by Wyndham Santa Fe

La Quinta Inn by Wyndham Santa Fe
3.0 star property
Southside, 8.3 km from Guadalupe District
7.0 out of 10, Good, (1605)
"Spacious parking and an excellent breakfast. Hotel is located in a prime area"
United States
Ramasamy
The price is €64
includes taxes & fees
11 Jan - 12 Jan 2026
La Quinta Inn by Wyndham Santa Fe
Rooftop bar
Drury Plaza Hotel in Santa Fe

Drury Plaza Hotel in Santa Fe

Drury Plaza Hotel in Santa Fe
3.5 star property
Downtown Santa Fe, 1.4 km from Guadalupe District
9.6 out of 10, Exceptional, (1425)
"Very nice place to stay would recommend highly"
United States
Lisa Maxwell
The price is €146
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Plaza Hotel in Santa Fe
Meeting facility
Inn at Santa Fe, SureStay Collection by Best Western

Inn at Santa Fe, SureStay Collection by Best Western

Inn at Santa Fe, SureStay Collection by Best Western
3.0 star property
Southside, 11 km from Guadalupe District
8.6 out of 10, Excellent, (2080)
"Great customer service, clean rooms, and a great breakfast.⭐️⭐️⭐️⭐️ "
United States
Anna
The price is €70
includes taxes & fees
3 Jan - 4 Jan 2026
Inn at Santa Fe, SureStay Collection by Best Western
Outdoor pool, pool umbrellas, pool loungers
Hilton Vacation Club Villas de Santa Fe

Hilton Vacation Club Villas de Santa Fe

Hilton Vacation Club Villas de Santa Fe
3.0 star property
Northeast Santa Fe, 1 km from Guadalupe District
9.2 out of 10, Wonderful, (1005)
"It's a great place to stay! "
United States
Tonya
The price is €85
includes taxes & fees
22 Jan - 23 Jan 2026
Hilton Vacation Club Villas de Santa Fe
Suite, 1 King Bed | View from room
Hilton Santa Fe Buffalo Thunder

Hilton Santa Fe Buffalo Thunder

Hilton Santa Fe Buffalo Thunder
4.0 star property
19.9 km from Guadalupe District
8.8 out of 10, Excellent, (1003)
"Room was clean and staff was friendly"
United States
Ursula
The price is €106
includes taxes & fees
14 Jan - 15 Jan 2026
Hilton Santa Fe Buffalo Thunder
Front of property
Inn and Spa at Loretto

Inn and Spa at Loretto

Inn and Spa at Loretto
4.0 star property
Downtown Santa Fe, 1.1 km from Guadalupe District
9.0 out of 10, Wonderful, (1000)
"Great staff - rooms are great but try to get mountain views. VERY dog friendly. "
United States
John
The price is €158
includes taxes & fees
5 Jan - 6 Jan 2026
Inn and Spa at Loretto
Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas
Hotel Glorieta

Hotel Glorieta

Hotel Glorieta
3.5 star property
1.6 km from Guadalupe District
8.0 out of 10, Very good, (48)
"Loved the decor"
United States
Marian
The price is €118
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Glorieta
Free buffet breakfast
Holiday Inn Express & Suites Santa Fe by IHG

Holiday Inn Express & Suites Santa Fe by IHG

Holiday Inn Express & Suites Santa Fe by IHG
2.5 star property
Southside, 6.3 km from Guadalupe District
9.0 out of 10, Wonderful, (863)
"Nice hotel. Very friendly staff."
United States
Kathy
The price is €100
includes taxes & fees
7 Jan - 8 Jan 2026
Holiday Inn Express & Suites Santa Fe by IHG
Dining
Eldorado Hotel & Spa

Eldorado Hotel & Spa

Eldorado Hotel & Spa
4.0 star property
Downtown Santa Fe, 0.8 km from Guadalupe District
8.8 out of 10, Excellent, (1036)
"Great location and hotel"
United States
Steven
The price is €137
includes taxes & fees
6 Jan - 7 Jan 2026
Eldorado Hotel & Spa
Lobby sitting area
Motel 6 Santa Fe, NM - Downtown

Motel 6 Santa Fe, NM - Downtown

Motel 6 Santa Fe, NM - Downtown
2.0 star property
Railyard Arts District, 0.5 km from Guadalupe District
7.8 out of 10, Good, (1002)
"Room was nice, easy check in."
United States
Alex
The price is €62
includes taxes & fees
6 Jan - 7 Jan 2026
Motel 6 Santa Fe, NM - Downtown
Suite, 1 King Bed
La Fonda on the Plaza

La Fonda on the Plaza

La Fonda on the Plaza
4.0 star property
Downtown Santa Fe, 1.1 km from Guadalupe District
9.2 out of 10, Wonderful, (1046)
"The rooms were exceptionally well maintained and the dining room served wonderful food. "
United States
Sara
The price is €140
includes taxes & fees
4 Jan - 5 Jan 2026
La Fonda on the Plaza
Premium bedding, individually decorated, individually furnished, desk
El Rey Court

El Rey Court

El Rey Court
3.0 star property
3.2 km from Guadalupe District
8.8 out of 10, Excellent, (1000)
"Staff was great!"
United States
cedric
The price is €130
includes taxes & fees
14 Jan - 15 Jan 2026
El Rey Court
Outdoor pool, a heated pool, pool loungers
Inn of the Governors

Inn of the Governors

Inn of the Governors
3.5 star property
Downtown Santa Fe, 0.9 km from Guadalupe District
9.6 out of 10, Exceptional, (1475)
"We loved everything about this hotel! The staff was super friendly and location was perfect! "
United States
Elizabeth
The price is €146
includes taxes & fees
4 Jan - 5 Jan 2026
Inn of the Governors
Exterior
Hotel Chimayo de Santa Fe

Hotel Chimayo de Santa Fe

Hotel Chimayo de Santa Fe
3.5 star property
Downtown Santa Fe, 1.2 km from Guadalupe District
9.2 out of 10, Wonderful, (1000)
"Location is incredible - half a block from the plaza, which makes the reasonable rate outstanding. Also, the fact that it's one of the few places with safe, FREE parking is a big plus. Will stay again."
United States
Corinne
The price is €125
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Chimayo de Santa Fe
Seasonal outdoor pool
Hilton Santa Fe Historic Plaza

Hilton Santa Fe Historic Plaza

Hilton Santa Fe Historic Plaza
4.0 star property
Downtown Santa Fe, 0.8 km from Guadalupe District
8.2 out of 10, Very good, (1003)
"Beautifully maintained- incredibly helpful staff and the perfect location to see the historic plaza and more. "
United States
Patricia
The price is €120
includes taxes & fees
19 Jan - 20 Jan 2026
Hilton Santa Fe Historic Plaza
Exterior
Hotel Santa Fe

Hotel Santa Fe

Hotel Santa Fe
4.0 star property
Railyard Arts District, 0.5 km from Guadalupe District
9.2 out of 10, Wonderful, (1089)
"Lovely stay"
United States
Richard
The price is €149
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Guadalupe District

Find the best Guadalupe District areas for the activities you enjoy most.

Downtown Santa Fe

Visitors to Downtown Santa Fe rave about its fascinating museums, popular shops and acclaimed art galleries. You might also want to make some time to see Santuario De Nuestra Senora de Guadalupe or Lensic Performing Arts Center while you're exploring the neighbourhood.

Southside

Southside is known for its popular shops, and with sights like Meow Wolf and Greer Garson Theater Center, you won't get bored spending a day wandering around this part of Santa Fe.

Canyon Road showing art and interior views

Historic Eastside

While visiting Historic Eastside, you might make a stop by sights like Canyon Road and Edition ONE Gallery.

Tesuque

Tesuque is noteworthy for its spas, and you can make a stop at top attractions like Glenn Green Galleries & Sculpture Garden and Shidoni Foundry.

Northeast Santa Fe

While Northeast Santa Fe isn't home to many top sights, New Mexico Museum of Art and Cathedral Basilica of Saint Francis of Assisi are some notable places to visit nearby.

Top Guadalupe District Hotel Reviews

La Fonda on the Plaza

La Fonda on the Plaza

10/10 Excellent
"The staff was friendly, professional and helpful. Location of the property is excellent. Coctails in the lounge were great & it was fun watching the eclectic guests. The room was nice with enough space. The overall ambiance felt special."
Felisa 1-night trip
Posted 3 days ago
La Fonda on the Plaza

Frequently asked questions

What's it like in Guadalupe District?
You'll be sure to have fun exploring Santa Fe's Guadalupe District neighbourhood. Make sure that you visit Santa Fe Railyard and Santuario De Nuestra Senora de Guadalupe as part of your Guadalupe District travel plans.
What's a favourite place to stay in Guadalupe District?
Based on Expedia customer reviews, Guadalupe Inn is the highest ranked property in Guadalupe District. This hotel is a short 14-minute walk from Santa Fe Plaza, and it offers free breakfast and free WiFi.
How many hotels are there in the Guadalupe District area?
If you're searching for places to stay in Santa Fe, Expedia has something to meet your needs with 66 Guadalupe District hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Guadalupe District, will I receive a refund?
Yes! You'll find that most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to get the best options available in Guadalupe District.
What can I see and do in this Santa Fe neighbourhood?
Sights like El Museo Cultural, Art Vault and TAI Modern can be part of your cultural tour of Guadalupe District. As you're discovering the neighbourhood, Santa Fe Railyard and Santuario De Nuestra Senora de Guadalupe are some other places worth a visit. Santa Fe Farmers Market, SITE Santa Fe and Harrell House of Natural Oddities and Bug Museum are just a few of the places to visit in and around Guadalupe District. While you're out sightseeing, Andrea Fisher Fine Pottery and Lensic Performing Arts Center are a couple of additional sights to visit in Santa Fe.
How can I get around Guadalupe District and the greater Santa Fe area?
If you want to head out of town, you can hop aboard a train at Santa Fe Depot.