Isla Grande Hotel Guide - Luxury Hotels in Isla Grande, Colón

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Isla Grande Luxury Hotels

This weekend
Next weekend
No exact matches found, but these alternatives could be just right

Recommended hotels in Isla Grande

Deluxe Beachfront 4-bedroom house in Colón Province

Deluxe Beachfront 4-bedroom house in Colón Province
Colón Province
The price is €341
includes taxes & fees
23 Dec - 24 Dec
Deluxe Beachfront 4-bedroom house in Colón Province

Hotel Cocotal

Hotel Cocotal
2.5 star property
Isla Grande
10.0 out of 10, Exceptional, (3)
"Beautiful views, great service "
United States
Israel
The price is €76
includes taxes & fees
23 Dec - 24 Dec
Hotel Cocotal

HOTEL ISLA GRANDE

HOTEL ISLA GRANDE
3.0 star property
Isla Grande
5.0 out of 10, (4)
"They would not check me in "
United States
Carl
The price is €88
includes taxes & fees
23 Dec - 24 Dec
HOTEL ISLA GRANDE

Ciel y Miel

Ciel y Miel
3.0 star property
Cacique
10.0 out of 10, Exceptional, (9)
"Love this place and would return back numerous times"
United States
Sean
Ciel y Miel

Ranchos de Chalia

Ranchos de Chalia
3.0 star property
Puerto Lindo
9.8 out of 10, Exceptional, (11)
"Perfect location"
United States
Juan
The price is €110
includes taxes & fees
2 Jan - 3 Jan 2026
Ranchos de Chalia

Casa Congo - Rayo Verde - Restaurante

Casa Congo - Rayo Verde - Restaurante
3.0 star property
Portobelo
9.0 out of 10, Wonderful, (108)
"Great location and staff "
United States
Oleg
The price is €70
includes taxes & fees
28 Dec - 29 Dec
Casa Congo - Rayo Verde - Restaurante

Caribbean getaway: beach cottage just on the sand

Caribbean getaway: beach cottage just on the sand
Palenque
10.0 out of 10, Exceptional, (1)
"The beach view was perfect! I loved hearing the waves all day and throughout the night. My dog and I enjoyed everything and felt very comfortable. "
United States
Beth N.
The price is €273
includes taxes & fees
28 Dec - 29 Dec
Caribbean getaway: beach cottage just on the sand

Charming 3-bedroom villa with AC and WiFi in soothing Río Hato

Charming 3-bedroom villa with AC and WiFi in soothing Río Hato
Río Hato
The price is €420
includes taxes & fees
24 Dec - 25 Dec
Charming 3-bedroom villa with AC and WiFi in soothing Río Hato

Cabaña La Punta op het Strand!!

Cabaña La Punta op het Strand!!
Colón Province
The price is €149
includes taxes & fees
23 Dec - 24 Dec
Cabaña La Punta op het Strand!!

BEAUTIFUL APARTMENT IN FRONT OF THE SEA

BEAUTIFUL APARTMENT IN FRONT OF THE SEA
Portobelo
8.0 out of 10, Very good, (3)
"All of it! Gabriel is a marvelous host; absolutely above and beyond. The house is lovely, very unique, and the location, right on the water, superb. We'll be back!"
United States
Rosa M.
The price is €156
includes taxes & fees
23 Dec - 24 Dec
BEAUTIFUL APARTMENT IN FRONT OF THE SEA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Isla Grande Hotel Reviews

Frequently asked questions

Are you looking for a luxury hotel for your stay in Isla Grande?
Expedia can help you get a flight to Panama City (PTY-Tocumen Intl.) airport or Panama City (PAC-Marcos A. Gelabert Intl.) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are important when you plan a holiday, so we make it easy to get what you need to make your stay relaxing and comfortable. If you want an upscale hotel that has fine dining, a spa or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that Isla Grande has to offer.
What's the best high-end place to stay in Isla Grande?
Ordovician Beach Resort is a luxury resort with a private beach and 2 restaurants, and it's a popular choice for Expedia travellers looking for an elegant place to stay.
When can I expect good weather in Isla Grande?
Planning for the weather is a good way to make your trip to Isla Grande relaxing and enjoyable, especially when you're splurging. The hottest months are usually May and September, with an average temperature of 27°C, while the coldest months are January and February, with an average of 26°C. The rainiest months in Isla Grande are November, July, August and October, with each month seeing an average of 350 mm of rainfall.
What's there to see and do in Isla Grande?
When you're in Isla Grande, enjoy exploring the sights and attractions here including Isla Mamey, Blanca Beach and Portobelo National Park. If you have a little extra time during your trip, you might want to check out San Felipe Church and Playa La Angosta.