Pine Bluff Hotel Guide - Jefferson Regional Medical Center hotels in Pine Bluff, United States of America.

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Tonight
31 Dec - 1 Jan
Tomorrow
1 Jan - 2 Jan
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

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Our top choices for Jefferson Regional Medical Center hotels

Terrace/patio
Hampton Inn and Suites Pine Bluff

Hampton Inn and Suites Pine Bluff

Hampton Inn and Suites Pine Bluff
2.5 star property
1.9 km from Jefferson Regional Medical Center
8.8 out of 10, Excellent, (681)
"Nice comfortable stay"
United States
Bellindia
The price is €87
includes taxes & fees
22 Jan - 23 Jan 2026
Hampton Inn and Suites Pine Bluff
Deluxe House, 5 Bedrooms, Non Smoking
Pine Bluff

Pine Bluff

Pine Bluff
3.0 star property
0.4 km from Jefferson Regional Medical Center
The price is €586
includes taxes & fees
4 Jan - 5 Jan 2026
Pine Bluff
Lobby
Comfort Inn & Suites Pine Bluff

Comfort Inn & Suites Pine Bluff

Comfort Inn & Suites Pine Bluff
2.5 star property
4.1 km from Jefferson Regional Medical Center
8.0 out of 10, Very good, (362)
"Great room and service"
United States
Gloria
The price is €70
includes taxes & fees
12 Jan - 13 Jan 2026
Comfort Inn & Suites Pine Bluff
Free buffet breakfast
Holiday Inn Express Hotel & Suites Pine Bluff / Pines Mall by IHG

Holiday Inn Express Hotel & Suites Pine Bluff / Pines Mall by IHG

Holiday Inn Express Hotel & Suites Pine Bluff / Pines Mall by IHG
2.5 star property
5.1 km from Jefferson Regional Medical Center
8.2 out of 10, Very good, (686)
"Coffee could be better, Columbian"
United States
Jim
The price is €81
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express Hotel & Suites Pine Bluff / Pines Mall by IHG
Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave
Best Western Presidential Hotel & Suites

Best Western Presidential Hotel & Suites

Best Western Presidential Hotel & Suites
2.5 star property
5.4 km from Jefferson Regional Medical Center
8.0 out of 10, Very good, (779)
"Nice and quiet, but the pillows were uncomfortably small. "
United States
Tracey
The price is €70
includes taxes & fees
3 Jan - 4 Jan 2026
Best Western Presidential Hotel & Suites
Reception
Super 8 by Wyndham Pine Bluff

Super 8 by Wyndham Pine Bluff

Super 8 by Wyndham Pine Bluff
2.0 star property
5.3 km from Jefferson Regional Medical Center
7.4 out of 10, Good, (326)
"The staff were friendly and accommodating. They made sure your stay was the best"
United States
Shanika
The price is €60
includes taxes & fees
12 Jan - 13 Jan 2026
Super 8 by Wyndham Pine Bluff
Desk, laptop workspace, free WiFi, bed sheets
Towneplace Suites By Marriott White Hall

Towneplace Suites By Marriott White Hall

Towneplace Suites By Marriott White Hall
3.0 star property
11.8 km from Jefferson Regional Medical Center
9.4 out of 10, Exceptional, (173)
"Clean room and property excellent staff very friendly and inviting "
United States
CHARLES
The price is €106
includes taxes & fees
11 Jan - 12 Jan 2026
Towneplace Suites By Marriott White Hall
Reception
Quality Inn & Suites Pine Bluff

Quality Inn & Suites Pine Bluff

Quality Inn & Suites Pine Bluff
2.5 star property
4.7 km from Jefferson Regional Medical Center
6.6 out of 10, (233)
"Friendly staff "
United States
Herbert
The price is €56
includes taxes & fees
12 Jan - 13 Jan 2026
Quality Inn & Suites Pine Bluff
Business centre
Days Inn & Suites by Wyndham Pine Bluff

Days Inn & Suites by Wyndham Pine Bluff

Days Inn & Suites by Wyndham Pine Bluff
2.0 star property
5.5 km from Jefferson Regional Medical Center
6.4 out of 10, (660)
"Everything was perfect "
United States
Amecia
The price is €58
includes taxes & fees
1 Jan - 2 Jan 2026
Days Inn & Suites by Wyndham Pine Bluff
Premium bedding, desk, laptop workspace, free WiFi
Motel 6 Pine Bluff, AR

Motel 6 Pine Bluff, AR

Motel 6 Pine Bluff, AR
2.0 star property
5.4 km from Jefferson Regional Medical Center
6.6 out of 10, (559)
"Second time staying here and staff is friendly. "
United States
Juanita
The price is €60
includes taxes & fees
1 Jan - 2 Jan 2026
Motel 6 Pine Bluff, AR
Lobby
Econo Lodge Pine Bluff

Econo Lodge Pine Bluff

Econo Lodge Pine Bluff
2.0 star property
5.3 km from Jefferson Regional Medical Center
6.2 out of 10, (166)
"It was affordable and ok "
United States
Edward
The price is €57
includes taxes & fees
7 Jan - 8 Jan 2026
Econo Lodge Pine Bluff
Front of property – evening/night
Redwood Inn and Suites

Redwood Inn and Suites

Redwood Inn and Suites
2.0 star property
10.9 km from Jefferson Regional Medical Center
7.2 out of 10, Good, (35)
"Room was clean and staff were helpful"
United States
Cynthia
The price is €63
includes taxes & fees
1 Jan - 2 Jan 2026
Redwood Inn and Suites
Exterior
Holiday Inn Express and Suites White Hall by IHG

Holiday Inn Express and Suites White Hall by IHG

Holiday Inn Express and Suites White Hall by IHG
2.5 star property
10.5 km from Jefferson Regional Medical Center
9.2 out of 10, Wonderful, (589)
"Great Staff, good location, rate was reasonable and the room was clean, overall, it was a good experience"
United States
Keith
The price is €93
includes taxes & fees
25 Jan - 26 Jan 2026
Holiday Inn Express and Suites White Hall by IHG
Desk, iron/ironing board, free WiFi, bed sheets
Super 8 by Wyndham White Hall

Super 8 by Wyndham White Hall

Super 8 by Wyndham White Hall
2.0 star property
11 km from Jefferson Regional Medical Center
7.2 out of 10, Good, (420)
"Rooms were large and clean. Parking was convenient. Breakfast options were limited."
United States
Frank
The price is €58
includes taxes & fees
6 Jan - 7 Jan 2026
Super 8 by Wyndham White Hall
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Jefferson Regional Medical Center Hotel Reviews

Holiday Inn Express and Suites White Hall by IHG

Holiday Inn Express and Suites White Hall by IHG

10/10 Excellent
"The rooms were clean, the staff was exceptionally helpful and kind."
Jamie 2-night trip
Posted 1 day ago
Holiday Inn Express and Suites White Hall by IHG

Hotels near other Jefferson Regional Medical Center attractions

Central Park

Explore the great outdoors at Central Park, a lovely green space in Pine Bluff. Experience the museums and art scene in this family-friendly area.
See properties

Bloom Tennis Center

Catch an event at Bloom Tennis Center during your trip to Pine Bluff. Experience the museums and art scene in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Jefferson Regional Medical Center?
Jefferson Regional Medical Center is located in Pine Bluff. If you're looking for a convenient place to stay, take a look at the 5 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near Jefferson Regional Medical Center?
Adjacent to Jefferson Regional Medical Center, Pine Bluff is one of the top choices for your stay based on our traveller data, and this holiday home offers free parking and in-room kitchens. Other good choices within 5 miles include Hampton Inn and Suites Pine Bluff and Days Inn & Suites by Wyndham Pine Bluff.
How many hotels will I be able to find near Jefferson Regional Medical Center?
Expedia has 5 hotels and other accommodation options within a mile from Jefferson Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Jefferson Regional Medical Center, will I receive a refund?
Yes! Most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Add dates, click "Search", then you can filter by "fully refundable" to review the best options available near Jefferson Regional Medical Center.
What can I see and do near Jefferson Regional Medical Center?
Pine Bluff /Jefferson County Historical Museum, Arkansas Railroad Museum and Arkansas Entertainers Hall of Fame feature captivating exhibits. Consider spending a leisurely afternoon outside at Delta Rivers Nature Center, Central Park or Belmont Park. Explore nature at Lake Pine Bluff and Midland Lake.