La Jolla Hotel Guide. Hotels in La Jolla Mesa, La Jolla, United States of America

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Tonight
17 Dec - 18 Dec
Tomorrow
18 Dec - 19 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

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Our top choices for La Jolla Mesa hotels

Standard Room, 1 King Bed, Non Smoking, Bay View
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
13.7 km from La Jolla Mesa
8.8 out of 10, Excellent, (744)
"Friendly staff and clean rooms. "
Canada
Justine
The price is €107
includes taxes & fees
24 Dec - 25 Dec
The DEXTRO Little Italy, BW Premier Collection
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
15 km from La Jolla Mesa
9.4 out of 10, Exceptional, (1000)
"Great location "
United States
Mohammad
The price is €113
includes taxes & fees
4 Jan - 5 Jan 2026
Staypineapple, Hotel Z, Gaslamp San Diego
Exterior
Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
9.5 km from La Jolla Mesa
8.2 out of 10, Very good, (1908)
"Great stay "
United States
Vanessa
The price is €74
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn San Diego Old Town
Room, 1 King Bed with Sofa bed, Marina View | View from room
Sheraton San Diego Resort

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
11.5 km from La Jolla Mesa
8.4 out of 10, Very good, (3161)
"Great stay! "
United States
Melissa
The price is €135
includes taxes & fees
22 Dec - 23 Dec
Sheraton San Diego Resort
Lobby
Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
8 km from La Jolla Mesa
7.4 out of 10, Good, (4116)
"Room was very clean and staff very pleasant "
Canada
Brian
The price is €83
includes taxes & fees
24 Dec - 25 Dec
Wyndham Garden San Diego Near SeaWorld
2 outdoor pools, open 6 AM to 10:00 PM, pool cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
14.8 km from La Jolla Mesa
9.2 out of 10, Wonderful, (1951)
"Amazing stay. Absolutely perfect "
United States
Wayne
The price is €202
includes taxes & fees
24 Dec - 25 Dec
Marriott Marquis San Diego Marina
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
13.5 km from La Jolla Mesa
8.4 out of 10, Very good, (6032)
"Always an amazing stay"
United States
Jana
The price is €158
includes taxes & fees
21 Dec - 22 Dec
Wyndham San Diego Bayside
Outdoor pool, pool umbrellas, pool loungers
Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown
2.5 star property
13.4 km from La Jolla Mesa
8.2 out of 10, Very good, (2287)
"The room was great, the bed was comfortable."
United States
PAM
The price is €102
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn San Diego-Downtown
Exterior
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
14.5 km from La Jolla Mesa
9.0 out of 10, Wonderful, (2870)
"Great Location....tons of walking from the hotel Front desk were very nice and polite will be coming back for sure "
United States
Carlos
The price is €196
includes taxes & fees
22 Dec - 23 Dec
Manchester Grand Hyatt San Diego
Courtyard
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
13.2 km from La Jolla Mesa
8.4 out of 10, Very good, (1891)
"Excellent location"
United States
Paolo
The price is €99
includes taxes & fees
4 Jan - 5 Jan 2026
DoubleTree by Hilton San Diego - Del Mar
Lobby
Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach
2.5 star property
4.3 km from La Jolla Mesa
9.0 out of 10, Wonderful, (802)
"good place to stay"
United States
Sisi
The price is €101
includes taxes & fees
21 Dec - 22 Dec
Fairfield Inn & Suites by Marriott San Diego Pacific Beach
Outdoor pool, pool loungers
Hilton San Diego Bayfront

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
15.5 km from La Jolla Mesa
8.6 out of 10, Excellent, (1870)
"Enjoyed my stay"
United States
Brandon
The price is €145
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton San Diego Bayfront
Reception
Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
11.9 km from La Jolla Mesa
8.8 out of 10, Excellent, (1562)
"Staff was great, easy check in and great location"
United States
Alysa
The price is €112
includes taxes & fees
5 Jan - 6 Jan 2026
Best Western Plus Island Palms Hotel & Marina
Reception
Kings Inn San Diego

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
10 km from La Jolla Mesa
8.8 out of 10, Excellent, (3567)
"Room was very clean, and the breakfast was good"
United States
Roxana
Kings Inn San Diego
Exterior
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter

Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
3.0 star property
15.1 km from La Jolla Mesa
9.0 out of 10, Wonderful, (1230)
"Very nice clean room and amenities and staff was pleasant and we love the location. "
United States
Arnold
The price is €135
includes taxes & fees
19 Dec - 20 Dec
Residence Inn by Marriott San Diego Downtown/Gaslamp Quarter
Outdoor pool, open 7:00 AM to 10:00 PM, pool cabanas (surcharge)
San Diego Mission Bay Resort

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
6.1 km from La Jolla Mesa
8.4 out of 10, Very good, (1311)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
United States
Haley
The price is €182
includes taxes & fees
1 Jan - 2 Jan 2026
San Diego Mission Bay Resort
Courtyard
Leucadia Beach Inn

Leucadia Beach Inn

Leucadia Beach Inn
2.5 star property
28.5 km from La Jolla Mesa
9.4 out of 10, Exceptional, (1000)
"Love this place!"
United States
BILL
The price is €83
includes taxes & fees
8 Jan - 9 Jan 2026
Leucadia Beach Inn
Outdoor pool
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
15.2 km from La Jolla Mesa
9.0 out of 10, Wonderful, (3155)
"Great stay"
United States
Laurence
The price is €207
includes taxes & fees
22 Dec - 23 Dec
Hard Rock Hotel San Diego
Hot springs
The Atwood Hotel San Diego - SeaWorld/Zoo

The Atwood Hotel San Diego - SeaWorld/Zoo

The Atwood Hotel San Diego - SeaWorld/Zoo
3.0 star property
10.1 km from La Jolla Mesa
8.0 out of 10, Very good, (1827)
"Clean and helpful staff, thank you !"
United States
Bora
The Atwood Hotel San Diego - SeaWorld/Zoo
Property grounds
Paradise Point Resort & Spa

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
5 km from La Jolla Mesa
8.6 out of 10, Excellent, (2355)
"Great stay, top tier service and excellent customer care "
Canada
Meriem
The price is €172
includes taxes & fees
18 Jan - 19 Jan 2026
Paradise Point Resort & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in La Jolla Mesa

Find the best La Jolla Mesa areas for the activities you enjoy most.

La Jolla Shores

While visiting La Jolla Shores, you might make a stop by sights like La Jolla Beach and Birch Aquarium.

La Jolla Cove featuring general coastal views and rugged coastline as well as a small group of people

Village of La Jolla

While visiting Village of La Jolla, you might make a stop by sights like La Jolla Cove and Museum of Contemporary Art San Diego.

Torrey Pines

Pristine beaches, ample dining options, and top golf courses are just a few top things to explore in Torrey Pines. A visit to Black's Beach or Torrey Pines Golf Course might round out your trip, and you can jump aboard the metro at UC San Diego Central Campus Station or VA Medical Center Station to get around town.

Country Club

Country Club might not have many top sights, but La Jolla Cove and Mount Soledad National Veterans Memorial are two attractions nearby that you can check out.

La Jolla

Beach Barber Tract

If you're spending some time in Beach Barber Tract, Windansea Beach and Marine Street Beach are top sights worth seeing.

Top La Jolla Mesa Hotel Reviews

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

10/10 Excellent
"Wonderful and polite staff great amenities and food Valet service like we never experienced before. Hard Rock hotel is definitely on my trip Calendar. "
David 3-night trip
Posted 1 day ago
Hard Rock Hotel San Diego

Frequently asked questions

What is La Jolla Mesa like?
Travellers to La Jolla's La Jolla Mesa neighbourhood will be sure to enjoy a stay here.
How many hotels will I be able to find in the La Jolla Mesa area?
If you're searching for places to stay in La Jolla, choose from one of Expedia's 15 hotels and other accommodation options in La Jolla Mesa.
If I need to cancel my hotel reservation in La Jolla Mesa, will I receive a refund?
Yes! Most hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to review the best options available in La Jolla Mesa.
What are the top things to see and do in La Jolla Mesa?
Tourmaline Surfing Park, Bird Rock and Pacific Beach are just a few of the places to visit in and around La Jolla Mesa. While you're out sightseeing, Crystal Pier and Mount Soledad National Veterans Memorial are a couple of additional sights to visit in La Jolla.