A sunset over a beach with a pier extending into the water.

Los Osos Hotel Guide - Hotels with Spa in Los Osos, California

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Check availability on Los Osos Hotels with Spa

Tonight
11 Oct - 12 Oct
Tomorrow
12 Oct - 13 Oct
Next weekend
16 Oct - 18 Oct
In two weeks
23 Oct - 25 Oct

Our top choices for Los Osos hotels with a spa

A bathroom with a stone sink, a mirror, and towels hanging on the wall.
A bar area with wooden beams, a colorful carpet, and a variety of bar stools.
A pool area with lounge chairs and umbrellas, a gazebo, and a waterfall.
A rustic bathroom with a stone sink, a toilet, and a shower area.

1. Madonna Inn

Madonna Inn
San Luis Obispo
  • Unwind at a unique spa retreat with six treatment rooms for aromatherapy, body scrubs, and massages in scenic comfort.
€181
includes taxes & fees
13 Oct - 14 Oct
Madonna Inn
A multi-story building with balconies, a fountain, and a patio area.
A stone wall with a statue, a wooden bench with a basket, and a mirror with a decorative frame.
A lobby with a stone wall, wooden chairs, a fireplace, and a signboard.
A hotel entrance with a stone facade, a tiled entrance, and a sign reading "Avila La Fonda Hotel".

2. Avila La Fonda Hotel

Avila La Fonda Hotel
Avila Beach
  • Revitalising seaside escape with private indoor hot tubs and spa services offers a wellness retreat just steps from the beach.
€207
includes taxes & fees
1 Nov - 2 Nov
Avila La Fonda Hotel
A modern interior with a reception desk, wooden shelving, and a variety of products on display.
A wooden pergola structure with a table and chairs underneath, surrounded by greenery.
A bar area with a long counter, multiple stools, and a large potted plant.
A hotel with a brick facade, large windows, and a well-lit entrance.

3. HOTEL CERRO, Autograph Collection

HOTEL CERRO, Autograph Collection
Downtown San Luis Obispo
  • Tranquil urban retreat with steam room, rooftop garden, and holistic treatments for a restorative wellness escape.
€307
includes taxes & fees
18 Oct - 19 Oct
HOTEL CERRO, Autograph Collection
A room with a dining table, chairs, a hanging plant, and a window with blinds.
A bedroom with a four-poster bed, a round table, two chairs, a ceiling fan, and a balcony with outdoor furniture.
A vintage wooden cabinet with glass doors, containing various items like wine bottles, a clock, and decorative objects.
A two-story building with a balcony, a sign indicating vacancy, and a parking lot with cars.

4. Cayucos Sunset Inn B&B

Cayucos Sunset Inn B&B
Cayucos
  • Relax in a beachside inn with private hot tubs, garden views, and rejuvenating couples massages.
€198
includes taxes & fees
13 Oct - 14 Oct
Cayucos Sunset Inn B&B
A spacious lobby with a wooden ceiling, a reception desk, seating areas, and large windows offering views of the outdoors.
A modern living room with a sofa, chairs, a coffee machine, and a dining area with a table and chairs.
An outdoor patio area with seating and planters, overlooking a hilly landscape.
A modern restaurant with wooden tables and chairs, a long counter with seating, and decorative plants.

5. Hotel San Luis Obispo

Hotel San Luis Obispo
Downtown San Luis Obispo
  • Savour serenity at this luxury hotel with a full-service spa offering daily treatments and couples' massage rooms in San Luis Obispo.
€379
includes taxes & fees
1 Nov - 2 Nov
Hotel San Luis Obispo
A multi-story hotel with balconies, a covered walkway, and a landscaped garden area.
A hotel room with two wooden beds, a desk with a chair, and a large window with curtains.
A reception area with a wooden floor, a reception desk, a vase with flowers, and an exit sign.
A spacious living room with a fireplace, a large TV, and a cozy seating area.

6. The Agrarian Hotel, BW Signature Collection

The Agrarian Hotel, BW Signature Collection
Arroyo Grande
  • Revitalise mind and body at this charming hotel with therapeutic spa services and a bubbling hot tub.
€156
includes taxes & fees
13 Oct - 14 Oct
The Agrarian Hotel, BW Signature Collection
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Choose what matters most at spa hotels in Los Osos

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Los Osos Hotel Reviews

Quality Suites Downtown San Luis Obispo

Quality Suites Downtown San Luis Obispo

8/10 Good
"Nice staff. Free parking. The room was very spacious. The beds were comfortable. Only think I hope the property changes: our room did not have rugs and the linoleum was very slippery. I like to take off my shoes when I get in the room and I almost fell. Other than that the room was very nice."
ana zahra 1-night trip
Posted 1 hour ago
Quality Suites Downtown San Luis Obispo
Pacific Point Resort

Pacific Point Resort

8/10 Good
"It had a beautiful view and was very clean, but some of the cliff‑side rooms had a strong, unpleasant smell. You couldn’t open the window or sit outside to enjoy the scenery. We informed the staff, and they moved us to a different room."
Mahtab 3-night trip
Posted 7 hours ago
Pacific Point Resort
SeaCrest OceanFront Hotel

SeaCrest OceanFront Hotel

10/10 Excellent
"Great property with amazing views. Great location to beach and Pismo Pier. On property restaurant “Blaze & Brew,” is fun and excellent food/menu. Rooms have been redone fairly recently and are spacious and comfortable. Plenty of amenities. Daily breakfast is good. We’d definitely stay again."
ROBERT 1-night trip
Posted 17 hours ago
SeaCrest OceanFront Hotel
Embassy Suites by Hilton San Luis Obispo

Embassy Suites by Hilton San Luis Obispo

10/10 Excellent
"Things get handle very professionally I have been coming to this place for two years Breakfast, spacious place and service Thank you!"
Ulises 1-night trip
Posted 1 day ago
Embassy Suites by Hilton San Luis Obispo
Sandcastle Hotel on the Beach

Sandcastle Hotel on the Beach

8/10 Good
"I felt overall the stay was good. There were a couple of things that stood out that could be changed. First, the upstairs balcony seating area was well arranged. However, the glass was really dirty. I’m not sure how often its cleaned but our entire stay it was dirty. Secondly the tv kept freezing up and even going out. I know that may be more of a network issue but just thought I would mention it. Overall, worth the price!"
Derrick 3-night trip
Posted 1 day ago
Sandcastle Hotel on the Beach
Vagabond Inn San Luis Obispo

Vagabond Inn San Luis Obispo

10/10 Excellent
"My neighbors played load music All night, certain it could be heard throughout the building. Its seems management turned a blind ear. Great spot close to all. Will stay again, price location cant beat it. A sleeping place when traveling for work."
teresa 2-night trip
Posted 2 days ago
Vagabond Inn San Luis Obispo

Frequently asked questions

Looking for a spa hotel in Los Osos?
Forget the stress of everyday life and book yourself a hotel with a spa. Discover the beaches in Los Osos—worth a picture or two! Take part in recreational activities such as golf during your holiday. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Los Osos?
Sea Pines Resort is a top spa hotel featuring a golf course, a bar and a restaurant. Spend an afternoon at the spa where you'll find deep-tissue massages, hot stone massages and couples treatments.
How many spa hotels will I find in Los Osos?
Among Expedia's 44 accommodation options in Los Osos, there is 1 spa hotel.
What's there to see and do in Los Osos?
Experience Los Osos with a stop at Montaña de Oro State Park, Morro Bay State Park and Los Osos Oaks State Reserve. If you have a bit of extra time while you're in the area, you might want to check out Morro Coast Audubon Society Sweet Springs Nature Preserve and Islay Creek Trail.
What is a Los Osos spa hotel?
Spa hotels in Los Osos provide lodging and have an on-site spa which offers services such as facials as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.