A sunset over a beach with a pier extending into the water.

Los Osos Hotel Guide - Hotels with Spa in Los Osos, California

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Our top choices for Los Osos hotels with a spa

Exterior

The Agrarian Hotel, BW Signature Collection

The Agrarian Hotel, BW Signature Collection
2.5 star property
Arroyo Grande
9.6 out of 10, Exceptional, (1,017 reviews)
  • cleanliness
    Revitalise mind and body at this charming hotel with therapeutic spa services and a bubbling hot tub.
The price is €170
includes taxes & fees
22 Jul - 23 Jul
The Agrarian Hotel, BW Signature Collection
Reception

Cayucos Sunset Inn B&B

Cayucos Sunset Inn B&B
3.5 star property
Cayucos
9.8 out of 10, Exceptional, (243 reviews)
  • cleanliness
    Relax in a beachside inn with private hot tubs, garden views, and rejuvenating couples massages.
The price is €253
includes taxes & fees
26 Jul - 27 Jul
Cayucos Sunset Inn B&B
Caveman | Bathroom

Madonna Inn

Madonna Inn
3.5 star property
San Luis Obispo
9.2 out of 10, Wonderful, (1,533 reviews)
  • cleanliness
    Unwind at a unique spa retreat with six treatment rooms for aromatherapy, body scrubs, and massages in scenic comfort.
The price is €277
includes taxes & fees
20 Jul - 21 Jul
Madonna Inn
Lobby

Hotel San Luis Obispo

Hotel San Luis Obispo
4.5 star property
Downtown San Luis Obispo
9.4 out of 10, Exceptional, (622 reviews)
  • cleanliness
    Savour serenity at this luxury hotel with a full-service spa offering daily treatments and couples' massage rooms in San Luis Obispo.
The price is €424
includes taxes & fees
20 Jul - 21 Jul
Hotel San Luis Obispo
Property grounds

Avila La Fonda Hotel

Avila La Fonda Hotel
4.0 star property
Avila Beach
9.6 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Revitalising seaside escape with private indoor hot tubs and spa services offers a wellness retreat just steps from the beach.
The price is €318
includes taxes & fees
2 Aug - 3 Aug
Avila La Fonda Hotel
Reception

HOTEL CERRO, Autograph Collection

HOTEL CERRO, Autograph Collection
4.0 star property
Downtown San Luis Obispo
9.2 out of 10, Wonderful, (489 reviews)
  • cleanliness
    Tranquil urban retreat with steam room, rooftop garden, and holistic treatments for a restorative wellness escape.
The price is €406
includes taxes & fees
10 Aug - 11 Aug
HOTEL CERRO, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Los Osos

Pool
Breakfast included

Top Los Osos Hotel Reviews

Oxford Suites Pismo Beach

Oxford Suites Pismo Beach

10/10 Excellent
"Excellent facility will definitely come back!!"
Kshitij 1-night trip
Posted less than an hour ago
Oxford Suites Pismo Beach

Frequently asked questions

Looking for a spa hotel in Los Osos?
Forget the stress of everyday life and book yourself a hotel with a spa. Discover the beaches in Los Osos—worth a picture or two! Take part in recreational activities such as golf during your holiday. Hotels with spas are a great way to take a break from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Los Osos?
Sea Pines Resort is a top spa hotel featuring a golf course, a bar and a restaurant. Spend an afternoon at the spa where you'll find deep-tissue massages, hot stone massages and couples treatments.
How many spa hotels will I find in Los Osos?
Among Expedia's 44 accommodation options in Los Osos, there is 1 spa hotel.
What's there to see and do in Los Osos?
Experience Los Osos with a stop at Morro Coast Audubon Society Sweet Springs Nature Preserve, Elfin Forest Preserve and Montaña de Oro State Park. If you have a bit of extra time while you're in the area, you might want to check out Morro Bay State Park and Los Osos Oaks State Reserve.
What is a Los Osos spa hotel?
Spa hotels in Los Osos provide lodging and have an on-site spa which offers services such as facials as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.