In the heart of Jeffersonville, Deaconess Guesthouse combines historical charm with modern luxury. Enjoy stunning riverfront views from the front porch and balcony or unwind in the hot tub under starry skies. This spacious retreat boasts indoor gaming zones, a unique dome, fully-equipped kitchens, SMART ROKU TVs in every living room and bedroom.
🌅 Deaconess Guesthouse | Historic Riverfront Luxury Estate | 8BR • Sleeps 24 • Hot Tub • Dome • Fire Pit • Minutes to Louisville
Welcome to Deaconess Guesthouse, a truly one-of-a-kind luxury riverfront estate where breathtaking Ohio River views, historic elegance, and modern comfort come together for an unforgettable stay. Nestled in the heart of historic Jeffersonville, this beautifully restored 1840s landmark offers the privacy and amenities of a boutique resort while placing you just minutes from Downtown Louisville, Churchill Downs, the Urban Bourbon Trail, NuLu, Whiskey Row, and the region's best dining, entertainment, and attractions.
Wake each morning to panoramic river views from the wraparound porch, sip coffee as boats drift by, spend your day exploring Kentucky's bourbon country and Louisville's iconic attractions, then return to your private retreat for evenings beneath the stars—soaking in the hot tub, sharing stories around the fire pit, dining under the signature dome, or relaxing on one of the scenic riverfront balconies.
Originally one of Indiana's earliest hospitals, this remarkable estate has been thoughtfully transformed into a luxury destination while preserving its rich architectural heritage. With 8 beautifully appointed bedrooms, 6 spa-inspired bathrooms, 4 fully equipped kitchens, and accommodations for up to 24 guests, it's the perfect setting for family reunions, Derby weekends, Bourbon Trail adventures, weddings, executive retreats, and milestone celebrations.
✨ Signature Luxury Amenities 🌅 Spectacular Ohio River Views: One of the property's most unforgettable features, enjoy sweeping river views from expansive wraparound porches, private balconies, and beautifully landscaped outdoor spaces that create the perfect backdrop for morning coffee, sunset cocktails, and peaceful moments throughout your stay. 🛏 Boutique Hotel-Style Accommodations: Eight thoughtfully designed bedrooms feature luxury mattresses, premium linens, elegant furnishings, and spacious layouts, providing exceptional comfort and privacy for every guest. 🛁 Spa-Inspired Bathrooms: Six beautifully renovated bathrooms combine timeless character with upscale finishes, offering a relaxing, hotel-quality experience. 🍽 Four Fully Equipped Kitchens: Whether preparing holiday meals, hosting a private chef, or enjoying an extended stay, four complete kitchens provide unmatched flexibility for large families and groups. 🔥 Resort-Style Outdoor Living: Designed to bring everyone together, your private outdoor retreat includes: - Private hot tub - Signature dome - Fire pit - Covered gazebo with outdoor dining - Wraparound porches - Scenic riverfront balconies - Beautifully landscaped gathering spaces 🏛 Historic Architecture, Modern Luxury: Original craftsmanship, soaring ceilings, grand historic details, and designer interiors blend seamlessly with modern conveniences and upscale amenities, creating a stay that feels both timeless and luxurious. 🎮 Entertainment & Gathering Spaces: Multiple designer living rooms, inviting gathering spaces, and game areas offer plenty of room for conversation, celebrations, and memorable evenings together. 🐾 Family & Pet-FriendlyThoughtfully equipped for guests of all ages—including well-behaved pets—so everyone can enjoy the experience together. 🚗 Convenient Parking: Private rear parking accommodates up to eight vehicles, with complimentary street parking directly in front of the estate.
📍 Explore Louisville & Southern Indiana Perfectly positioned in walkable downtown Jeffersonville, you'll be just minutes from the area's most celebrated destinations: 🏇 Churchill Downs & the Kentucky Derby Museum 🥃 Urban Bourbon Trail & world-renowned distilleries 🌆 Downtown Louisville 🍸 NuLu & Whiskey Row 🌉 Big Four Bridge & Waterfront Park 🍽 Award-winning restaurants, cafés, bourbon bars, breweries, and rooftop dining 🎶 Live music, festivals, and seasonal events 🛍 Boutique shopping and local markets 🎨 Museums and cultural attractions ✈ Louisville Muhammad Ali International Airport (SDF)
You'll also enjoy walking to Jeffersonville's charming riverfront, local coffee shops, restaurants, boutiques, parks, and scenic Riverwalk.
✨ More Than a Stay—A Luxury Riverfront Escape Deaconess Guesthouse is more than a vacation rental—it's an experience. From breathtaking river views and unforgettable sunsets to luxurious amenities and thoughtfully designed gathering spaces, every detail has been curated to create meaningful moments with the people who matter most.
Whether you're celebrating a special occasion, exploring Kentucky's legendary Bourbon Trail, attending the Kentucky Derby, or simply escaping for a relaxing waterfront getaway, Deaconess Guesthouse offers one of the Ohio River's most distinctive luxury retreats. We look forward to welcoming you.
** Please note: A strict cancellation policy applies for Derby and Bourbon & Beyond dates. **
★ CONVENIENT CENTRAL LOCATION Perfectly located just minutes from Louisville’s top attractions, restaurants, nightlife, and event venues:
• Big Four Walking Bridge — 0.4 mi (2 mins) • Downtown Louisville & 4th Street Live — 2.4 mi (6 mins) • KFC Yum! Center — 2.3 mi (7 mins) • Churchill Downs / Kentucky Derby — 7.7 mi (15 mins) • Waterfront Park — 3.4 mi (9 mins) • Louisville Airport (SDF) — 8.6 mi (10 mins) • Kentucky Exposition Center & Fairgrounds — ~6.5 mi (10–11 mins) • Kentucky Kingdom — 7.4 mi (13 mins) • Highland Festival Grounds — 8.5 mi (12 mins) • Louisville Mega Cavern — 10.2 mi (19 mins) • UPS Worldport — 11.2 mi (20 mins) • Valhalla Golf Club — 19 mi (27 mins) • Waverly Hills Sanatorium — 17 mi (30 mins)
Most destinations are just a quick 10–15 minute Uber/Lyft ride away.
★ 2026 TOP EVENTS
• Kentucky State Fair — Aug 20–30, 2026 • Big Four Arts Festival — Sep 12–13, 2026 • Louder Than Life Festival — Sep 17–20, 2026 • Bourbon & Beyond Festival — Sep 24–27, 2026 • St. James Court Art Show — Oct 3–4, 2026 • NuLu Fest — Oct 9–11, 2026 • Halloween & Haunted Attractions — Oct 24–31, 2026 • Thanksgiving Week Travel — Nov 25–29, 2026 • Light Up Louisville — Nov 27, 2026 • Christmas at the Frazier Museum — Dec 2026 • Louisville Ballet’s The Nutcracker — Dec 2026 • New Year’s Eve at Fourth Street Live! — Dec 31, 2026
★ 2026 TRADE SHOWS & MAJOR EVENTS
• Equip Exposition — Oct 20–23, 2026
NOTE: 1. 25+ to book. 2. House Rules Required: E-sign rental agreement and submit a $500 security hold via secure OwnerRez (placed 2 days before arrival, released 7 days after departure if no damage). 3. Cancellation Policy: Please be aware that a strict cancellation policy is in effect for bookings during the Kentucky Derby and Bourbon & Beyond festival dates. 4. No visitors unless pre-approved by the host. 5. Exterior cameras only (parking area & front door). No interior or backyard cameras. 6. Dome use: Not recommended during hot summer months. 7. No early check-in / late check-out on same-day turnovers. 8. When available: $100 (≤2 hrs), $250 (2–4 hrs), full night rate (>4 hrs). 9. Refunds: Non-Airbnb refunds are subject to a 3% payment processing fee. 10. Optional Concierge Services: Enhance your stay with our optional services, including grocery pre-stocking, a private chef experience, or custom-chauffeured Bourbon Trail tours. 11. House-trained pets are welcomed. We do charge $300 for 1st pet and $250 for the 2nd pet. (max 2 pets, 50lbs max weight limit each).
PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANKS!!
Property amenities
Pool/Spa
Hot tub
Internet
Available in the house: Free WiFi
Parking and transport
Car recommended
Parking on site
Kitchen
Coffee/tea maker
Cookware, dishware, and utensils
Dishwasher
Hob
Ice maker
Kitchen island
Microwave
Oven
Refrigerator
Spices
Toaster
Dining
Dining table
Bedrooms
8 bedrooms
Bedsheets provided
Sofa bed
Bathroom
6 bathrooms
Bathtub or shower
Hair dryer
Shower
Towels provided
Living spaces
Dining table
Fireplace
Living room
Entertainment
Books
Games
Smart TV
Outdoor areas
Balcony
Barbecue grill
Fenced yard
Firepit
Garden
Laundry
Laundry facilities
Washing machine
Work spaces
Desk
Desk chair
Comfort
Air conditioning
Heating
Pets
Pet friendly
Suitability/Accessibility
If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
Area rugs in public areas
Handrails in hallways
Handrails in stairways
Hardwood flooring in public areas
Smooth flooring in public areas
Thin carpet in public areas
Tile flooring in public areas
Well-lit path to entrance
Smoke-free property
Services and conveniences
Iron/ironing board
Location highlights
In the city centre
Near a hospital
Near a zoo
Near the marina
On a river
On the waterfront
Things to do
Arcade/game room
Water park
Casino nearby
Fishing nearby
Golfing nearby
Kayaking nearby
Motor boating nearby
Theme park nearby
Winery tours nearby
Safety features
Carbon monoxide detector (host has indicated there is a carbon monoxide detector on the property)
Smoke detector (host has indicated there is a smoke detector on the property)
First aid kit
Fire extinguisher
Deadbolt lock
General
Garden
Recycling
Some LED lighting used
Unit size: 5,800 square feet
Water-efficient showers
Water-efficient toilets
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You will receive an email from the host with check-in and check-out instructions
Information provided by the property may be translated using automated translation tools
Rules
Must sign rental agreement upon booking which will be sent via email
A $500 security hold will be placed 2 days prior to arrival and released 7 days after departure, if no damages are reported
Must follow all house rules listed in the end of the description and also on the rental agreement.
Pets
Pets are allowed
Service animals are welcome, and are exempt from fees
Note from host: Up to 2 pets 50lbs max.
Children and extra beds
Children are welcome
Events
No events allowed
Smoking
Smoking is not permitted
Important information
You need to know
This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
On-site parties or group events are strictly prohibited
Host has indicated that there is a carbon monoxide detector on the property
Host has indicated that there is a smoke detector on the property
Safety features at this property include a fire extinguisher, a first aid kit and a deadlock
This property is managed through our partner, Vrbo. You will receive an email from Vrbo with a link to a Vrbo account, where you can change or cancel your reservation
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.
We should mention
A car is recommended for transport to and from this property
About the area
Located in Jeffersonville, this holiday home is in the city centre and on the waterfront. KFC Yum Center and Louisville Slugger Museum are cultural highlights, and some of the area's popular attractions include Kentucky Kingdom and Louisville Zoo. Looking to enjoy an event or a game? See what's going on at L&N Federal Credit Union Stadium or Churchill Downs. Looking to get your feet wet? Kayaking, power boating and fishing adventures can be found near the property. Visit our Jeffersonville travel guide
How much does it cost to stay at 8BR Waterfront Getaway Bourbon Trail w/Dome HotTub Firepit Luxe Amenities Views?
As of 27 Jul 2026, prices found for a 1-night stay for 2 adults at 8BR Waterfront Getaway Bourbon Trail w/Dome HotTub Firepit Luxe Amenities Views on 16 Aug 2026 start from €2,135, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
How much is parking at 8BR Waterfront Getaway Bourbon Trail w/Dome HotTub Firepit Luxe Amenities Views?
On-site parking is available at the property.
What time is check-in at 8BR Waterfront Getaway Bourbon Trail w/Dome HotTub Firepit Luxe Amenities Views?
Check-in begins at 4:00 PM.
What time is check-out at 8BR Waterfront Getaway Bourbon Trail w/Dome HotTub Firepit Luxe Amenities Views?
Checkout is at 10:00 AM.
Where is 8BR Waterfront Getaway Bourbon Trail w/Dome HotTub Firepit Luxe Amenities Views located?
This family-friendly Jeffersonville holiday home is located on the waterfront, within a 10-minute walk of Ohio River Valley, Ohio River and Big Four Bridge. Atlantis Waterpark and Louisville Waterfront Park are also within 2 miles (3 km).
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We had a wonderful experience! Probably the best rental I've ever stayed in. It was very clean, wonderful amenities and the host was very attentive. Checking on us several times. We will highly recommend and hope to stay again!!
The house is big and unique. There are four areas that could be separate spaces - each includes a living area, kitchen, bathroom, and two bedrooms. We were able to gather together when we wanted to and have our own space to sleep. The teens enjoyed the hot tub, and the younger kids liked the games. The location is great. We walked along the river and to the hub of town. Highly recommend.
This house was perfect for our company. We were able to spread out and have our own rooms. The host was amazing! We unfortunately had scary weather while we were there and Kapil went above and beyond to make sure we were safe. Would definitely stay here again!
Kapil was a great host. Went out of the way to make sure we had everything we needed for a perfect trip! Enjoyed the location, backyard, space and game room upstairs. Thanks for everything, would definitely stay here again!
The house was perfect for our group. It was clean and the decor was beautiful. Judy s short ride to all of our Louisville destinations. The host was very responsive. We look forward to staying at this property again!
Property is fantastic. Very nicely appointed and equipped. The view of the Ohio River is fantastic and the backyard is set up for entertaining and fun! Great property and great owner communication.
Fantastic experience! The property was exactly as described and the booking experience smooth and easy. All of my questions were answers promptly. Check-in was a breeze with fantastic lighting outside when arriving after dark. The propertly is beautiful and our corporate group enjoyed the stay immensely. The property met every need we had from the private spaces, group gathering and meeting spaces and comfortable outdoor areas. The views along the river are gorgeous and sunrise over the river was spectacular. The kitchens met our needs when we cooked in and there are also great dining options nearby for eating out or carrying out. Will definately book here again!
We Absolutely Loved Our Stay at Deaconess Guesthouse!We loved everything about this house! The tall ceilings, comfortable sitting areas, and the beautiful color palettes in each unit made it such a special and relaxing place to stay. The promotional boards with bits of history were so fun to read and gave the home extra character.The coffee bar was a huge hit with our group, and the little touches like the ice bucket and fully stocked bathrooms (shampoo, conditioner, and body wash) were so appreciated. It made our stay effortless knowing that everything we needed—paper towels, toilet paper, sponges, towels—was already provided.The place was spotless when we arrived, and it was such a treat to have TVs in every room. We really enjoyed the hot tub, and when we had a small issue, someone came right away—not only to fix it but also to clean it thoroughly. The responsiveness was top-notch. Even when we asked for a vacuum, it was delivered immediately!This property is beautifully maintained and exceptionally well-managed. We would absolutely stay here again and highly recommend it to anyone visiting Jeffersonville or the Louisville area!
From the time of Booking Kapil was great at communicating. He was very professional and polite through out our stay, checking in and allowing us to reach out at our convenance. The property was as advertised. A quite location on the river with local bars and restaurants within walking distance. Our group enjoyed the backyard in the evenings playing corn hole and sitting around the fire. The place was very clean inside and out and all things where in working order. I would highly recommend for large groups as there is plenty of space to hangout or take a few minutes away from the group when you need it. I have stayed in a ton of VRBOs and this one is in my top 10 for overall value, host performance, and cleanliness.
Another great stay at The Deaconess House! This was a repeat stay for our annual sales and marketing strategic planning and everything about our stay was great! Communication prior to and during the stay was excellent. The property was as described, all 4 units were fully stocked and more than met our needs. We had 8 adults staying plus had visitors one evening for a special dinner and the home provided plenty of room for everyone. We will likely return for a third visit next year and we highly recommend this property!
Awesome location for enjoying the barges on the river, walking to the Big Four walking bridge, and dinner in Jeffersonville! We spent most of our time on the riverside porch with a breeze! The Deaconess Guest House is well cared for and we felt welcomed by the clean, well appointed living spaces.
We rented all four units of this home for a getaway with 19 people. We fit beyond perfectly in the rooms and the two sofa beds, which a friend of mine said she hasn’t slept that well in months. Having the four kitchens, extra bathrooms and fun outdoor area was the extra bonus. Location is great and there’s tons of parking. Kapil was easy to communicate with the entire weekend!
We have a large (16 person) family that was looking to vacation in the Louisville area. We found this place that could accommodate everyone under one roof. The location was great as it was only minutes from downtown Louisville. The pictures and description of the property were as advertised. The only issue we ran into were the lack of venthoods in the kitchens made cooking a little smokey at times. We would have loved to use the back yard but we were unable to due to the time of year (heat and mosquitoes). Overall the property was as advertised and we would definitely recommend for larger parties like ours.