Rochester Hotel Guide - Mayo Civic Center hotels in Rochester, United States of America.

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Our top choices for Mayo Civic Center hotels

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester, 0.2 km from Mayo Civic Center
9.6 out of 10, Exceptional, (546)
"Very courteous staff, loved the valet guy!"
United States
Jean
The price is €168
includes taxes & fees
9 Jan - 10 Jan 2026
Hilton Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester, 0.9 km from Mayo Civic Center
9.6 out of 10, Exceptional, (483)
"Room was large, clean, beds were comfortable. Downstairs cafe and seating areas were very comfortable."
United States
Ann
The price is €124
includes taxes & fees
2 Jan - 3 Jan 2026
TownePlace Suites by Marriott Rochester Mayo Clinic Area

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
2.5 star property
Kutzky Park, 2.3 km from Mayo Civic Center
9.6 out of 10, Exceptional, (677)
"Good place to stay when traveling to Mayo apots"
United States
Carolyn
The price is €87
includes taxes & fees
1 Jan - 2 Jan 2026
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

The Berkman

The Berkman
3.0 star property
Folwell, 2 km from Mayo Civic Center
9.6 out of 10, Exceptional, (372)
"Staff was great, as was the room."
United States
Scott
The price is €139
includes taxes & fees
24 Dec - 25 Dec
The Berkman

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
2.9 km from Mayo Civic Center
9.6 out of 10, Exceptional, (882)
"Great stay,clean and friendly"
United States
Janet
The price is €112
includes taxes & fees
1 Jan - 2 Jan 2026
Home2 Suites by Hilton Rochester Mayo Clinic Area

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
2.9 km from Mayo Civic Center
9.6 out of 10, Exceptional, (252)
"Rooms were clean staff was courteous. "
United States
Michael
The price is €125
includes taxes & fees
28 Dec - 29 Dec
Residence Inn by Marriott Rochester Mayo Clinic Area South

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 1.5 km from Mayo Civic Center
9.4 out of 10, Exceptional, (963)
"Rooms are comfortable and staff was was so professional and helpful."
United States
William
The price is €101
includes taxes & fees
25 Dec - 26 Dec
EVEN Hotel Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
Kutzky Park, 1.5 km from Mayo Civic Center
9.4 out of 10, Exceptional, (422)
"Early check in was definitely a plus since I flew from out of town. "
United States
Humberto
The price is €110
includes taxes & fees
25 Dec - 26 Dec
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester, 0.6 km from Mayo Civic Center
9.2 out of 10, Wonderful, (1006)
"Quick and easy check-in, walkable area and nice breakfast and accomodations. Would stay again!"
United States
Elizabeth
The price is €126
includes taxes & fees
24 Dec - 25 Dec
Hyatt House Rochester/Mayo Clinic Area

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester, 0.2 km from Mayo Civic Center
9.2 out of 10, Wonderful, (167)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is €154
includes taxes & fees
29 Dec - 30 Dec
Broadway Plaza, Trademark Collection by Wyndham

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park, 1.9 km from Mayo Civic Center
9.2 out of 10, Wonderful, (771)
"Clean room and housekeeping service was excellent"
United States
Dawn
The price is €82
includes taxes & fees
30 Dec - 31 Dec
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
3.0 star property
Kutzky Park, 1.9 km from Mayo Civic Center
9.2 out of 10, Wonderful, (477)
"Clean room, breakfast selection"
United States
Sonya
The price is €104
includes taxes & fees
29 Dec - 30 Dec
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.5 star property
2.7 km from Mayo Civic Center
9.2 out of 10, Wonderful, (454)
"The staff checking in and out were helpful and friendly. The room was clean, comfortable, and quiet. "
United States
Allison
The price is €95
includes taxes & fees
5 Jan - 6 Jan 2026
Candlewood Suites Rochester Mayo Clinic Area by IHG

Aspen Suites

Aspen Suites
3.0 star property
1.7 km from Mayo Civic Center
9.0 out of 10, Wonderful, (695)
"Room was clean and inviting and staff always willing to help"
United States
Maria del Carmen
The price is €170
includes taxes & fees
16 Jan - 17 Jan 2026
Aspen Suites

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
3 km from Mayo Civic Center
9.0 out of 10, Wonderful, (1011)
"We had a wonderful stay!"
United States
Sarah
The price is €81
includes taxes & fees
23 Jan - 24 Jan 2026
Hampton Inn Rochester-South

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
3.1 km from Mayo Civic Center
9.0 out of 10, Wonderful, (899)
"Good breakfast..shuttle service is excellent..super nice staff.."
United States
DALE K
The price is €66
includes taxes & fees
9 Jan - 10 Jan 2026
Econo Lodge Mayo Clinic Area

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester, 0.3 km from Mayo Civic Center
8.8 out of 10, Excellent, (892)
"Room was clean and comfortable Staff courteous Comfortable beds Great restaurant"
United States
Matney
The price is €78
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester, 0.3 km from Mayo Civic Center
8.8 out of 10, Excellent, (853)
"Everything was wonderful! Helpful, friendly staff, great location, nice amenities."
United States
kristi
The price is €105
includes taxes & fees
2 Jan - 3 Jan 2026
Hilton Garden Inn Rochester Downtown, MN

Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester, 0.7 km from Mayo Civic Center
8.8 out of 10, Excellent, (1000)
"Convenient, clean location and friendly staff"
United States
Kaushika
The price is €110
includes taxes & fees
25 Dec - 26 Dec
Brentwood Inn & Suites

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park, 2.1 km from Mayo Civic Center
8.8 out of 10, Excellent, (765)
"Clean room, friendly staff. The only minus is the lighting in the bathroom, way too dim. "
United States
Stacy
The price is €86
includes taxes & fees
25 Dec - 26 Dec
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mayo Civic Center Hotel Reviews

Hotels near other Mayo Civic Center attractions

Frequently asked questions

What's the area like around Mayo Civic Center?
Mayo Civic Center is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, take a look at the 133 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to Mayo Civic Center?
Adjacent to Mayo Civic Center, Kahler Grand Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Hyatt House Rochester/Mayo Clinic Area.
How many hotels should I expect to find near Mayo Civic Center?
Expedia has 133 hotels and other accommodation options within a mile from Mayo Civic Center.
If I need to cancel the hotel reservation for my stay near Mayo Civic Center, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Add dates, click "Search", then you can use the "fully refundable" filter to get the best deals available near Mayo Civic Center.
What can I see and do near Mayo Civic Center?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Assisi Heights and Plummer House. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.