La Crosse Hotel Guide - Mayo Clinic Health System - Franciscan Healthcare hotels in La Crosse, United States of America.

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Our top choices for Mayo Clinic Health System - Franciscan Healthcare hotels

Room 4 - The Rodolphe with Steam Shower
Hatchery Riverside Hotel & Event Venue

Hatchery Riverside Hotel & Event Venue

Hatchery Riverside Hotel & Event Venue
3.0 star property
Historic Downtown La Crosse, 1.9 km from Mayo Clinic Health System - Franciscan Healthcare
10.0 out of 10, Exceptional, (76)
"I would definitely stay here again great location beautiful rooms and very pleasant staff"
United States
Christine
The price is €172
includes taxes & fees
11 Jan - 12 Jan 2026
Hatchery Riverside Hotel & Event Venue
Indoor pool, pool loungers
Gundersen Hotel & Suites

Gundersen Hotel & Suites

Gundersen Hotel & Suites
2.5 star property
Powell-Poage-Hamilton, 1 km from Mayo Clinic Health System - Franciscan Healthcare
9.4 out of 10, Exceptional, (1000)
"Staff was courteous. Room was spacious and very quiet."
United States
Peggy
Gundersen Hotel & Suites
Lobby
The Charmant Hotel

The Charmant Hotel

The Charmant Hotel
4.0 star property
Historic Downtown La Crosse, 1.5 km from Mayo Clinic Health System - Franciscan Healthcare
9.6 out of 10, Exceptional, (1001)
"I love this hotel! The staff was friendly and courteous. "
United States
Scott
The price is €151
includes taxes & fees
11 Jan - 12 Jan 2026
The Charmant Hotel
Terrace/patio
Hampton Inn & Suites La Crosse Downtown

Hampton Inn & Suites La Crosse Downtown

Hampton Inn & Suites La Crosse Downtown
2.5 star property
Historic Downtown La Crosse, 1.6 km from Mayo Clinic Health System - Franciscan Healthcare
9.6 out of 10, Exceptional, (1001)
"Clean room, friendly staff, overall great stay"
United States
Emily
The price is €96
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites La Crosse Downtown
In-room safe, free WiFi, bed sheets
Home2 Suites by Hilton La Crosse

Home2 Suites by Hilton La Crosse

Home2 Suites by Hilton La Crosse
3.0 star property
Historic Downtown La Crosse, 1.2 km from Mayo Clinic Health System - Franciscan Healthcare
9.4 out of 10, Exceptional, (833)
"Everything was perfect, from the comfortable bed to the great breakfast. I would very much recommend this hotel. "
United States
Michael
The price is €91
includes taxes & fees
25 Jan - 26 Jan 2026
Home2 Suites by Hilton La Crosse
Lobby
Fairfield Inn & Suites by Marriott La Crosse Downtown

Fairfield Inn & Suites by Marriott La Crosse Downtown

Fairfield Inn & Suites by Marriott La Crosse Downtown
2.5 star property
Historic Downtown La Crosse, 1.1 km from Mayo Clinic Health System - Franciscan Healthcare
9.2 out of 10, Wonderful, (809)
"Fresh food and clean eatery"
United States
Kristine
The price is €103
includes taxes & fees
6 Jan - 7 Jan 2026
Fairfield Inn & Suites by Marriott La Crosse Downtown
Indoor pool
GrandStay Hotel & Suites

GrandStay Hotel & Suites

GrandStay Hotel & Suites
2.5 star property
Historic Downtown La Crosse, 1.7 km from Mayo Clinic Health System - Franciscan Healthcare
9.0 out of 10, Wonderful, (1042)
"Great location & nice large suite"
United States
Brooke
The price is €96
includes taxes & fees
5 Jan - 6 Jan 2026
GrandStay Hotel & Suites
Property amenity
Courtyard by Marriott La Crosse

Courtyard by Marriott La Crosse

Courtyard by Marriott La Crosse
3.0 star property
Historic Downtown La Crosse, 1.4 km from Mayo Clinic Health System - Franciscan Healthcare
9.0 out of 10, Wonderful, (547)
"Very comfortable bed in the room was spotless! We used the fitness center and that was also very nice and clean."
United States
Melissa
The price is €99
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott La Crosse
Exterior detail
Radisson Hotel La Crosse

Radisson Hotel La Crosse

Radisson Hotel La Crosse
3.5 star property
Historic Downtown La Crosse, 1.5 km from Mayo Clinic Health System - Franciscan Healthcare
8.6 out of 10, Excellent, (1013)
"Clean hotel and great staff. Love staying there"
United States
Sarah
The price is €116
includes taxes & fees
8 Jan - 9 Jan 2026
Radisson Hotel La Crosse
Exterior
Candlewood Suites La Crosse N by IHG

Candlewood Suites La Crosse N by IHG

Candlewood Suites La Crosse N by IHG
2.5 star property
Lower Northside, 2.2 km from Mayo Clinic Health System - Franciscan Healthcare
8.4 out of 10, Very good, (331)
"Very nice place to stay. "
United States
Keith
The price is €95
includes taxes & fees
28 Jan - 29 Jan 2026
Candlewood Suites La Crosse N by IHG
Iron/ironing board, free WiFi, bed sheets
Pearl Street Hotel & Suites

Pearl Street Hotel & Suites

Pearl Street Hotel & Suites
2.5 star property
Historic Downtown La Crosse, 1.3 km from Mayo Clinic Health System - Franciscan Healthcare
8.0 out of 10, Very good, (366)
"Great location and value."
United States
Rob
Pearl Street Hotel & Suites
Front of property
Adriatic

Adriatic

Adriatic
2.0 star property
3 km from Mayo Clinic Health System - Franciscan Healthcare
7.2 out of 10, Good, (23)
"The room could have been cleaner but overall it was a good stay."
United States
Tim
The price is €73
includes taxes & fees
1 Jan - 2 Jan 2026
Adriatic
Interior entrance
Welch Motel

Welch Motel

Welch Motel
2.5 star property
3.2 km from Mayo Clinic Health System - Franciscan Healthcare
7.0 out of 10, Good, (285)
"Everything was fine. Would stay again"
United States
Ronald
The price is €57
includes taxes & fees
12 Jan - 13 Jan 2026
Welch Motel
Standard Room, 2 Queen Beds, Non Smoking
Rodeway Inn La Crosse

Rodeway Inn La Crosse

Rodeway Inn La Crosse
2.0 star property
Lower Northside, 2.7 km from Mayo Clinic Health System - Franciscan Healthcare
5.8 out of 10, (111)
"Clean"
United States
Austin
The price is €54
includes taxes & fees
12 Jan - 13 Jan 2026
Rodeway Inn La Crosse
Lunch and dinner served
Best Western Plus LaCrescent / LaCrosse

Best Western Plus LaCrescent / LaCrosse

Best Western Plus LaCrescent / LaCrosse
2.5 star property
5.9 km from Mayo Clinic Health System - Franciscan Healthcare
9.2 out of 10, Wonderful, (508)
"Great location and a lot of amenities. The staff was great and we enjoyed the pub. "
United States
Nary
The price is €94
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus LaCrescent / LaCrosse
Hypo-allergenic bedding, desk, iron/ironing board, free WiFi
Country Inn & Suites by Radisson, La Crosse, WI

Country Inn & Suites by Radisson, La Crosse, WI

Country Inn & Suites by Radisson, La Crosse, WI
2.5 star property
Northside, 5.5 km from Mayo Clinic Health System - Franciscan Healthcare
8.8 out of 10, Excellent, (1002)
"Great staff and good location "
United States
David
The price is €64
includes taxes & fees
25 Jan - 26 Jan 2026
Country Inn & Suites by Radisson, La Crosse, WI
Lobby
Quality Inn La Crosse North

Quality Inn La Crosse North

Quality Inn La Crosse North
2.5 star property
Northside, 5.1 km from Mayo Clinic Health System - Franciscan Healthcare
8.0 out of 10, Very good, (1000)
"Great place to stay"
United States
Dave
The price is €61
includes taxes & fees
11 Jan - 12 Jan 2026
Quality Inn La Crosse North
Desk, free cots/infant beds, free WiFi, bed sheets
Super 8 by Wyndham La Crosse

Super 8 by Wyndham La Crosse

Super 8 by Wyndham La Crosse
2.5 star property
Northside, 4.8 km from Mayo Clinic Health System - Franciscan Healthcare
7.8 out of 10, Good, (1005)
"Everything was perfect and the staff was excellent "
United States
Justin
The price is €55
includes taxes & fees
11 Jan - 12 Jan 2026
Super 8 by Wyndham La Crosse
Free continental breakfast
Holiday Inn Express & Suites Onalaska La Crosse Area by IHG

Holiday Inn Express & Suites Onalaska La Crosse Area by IHG

Holiday Inn Express & Suites Onalaska La Crosse Area by IHG
2.5 star property
9.1 km from Mayo Clinic Health System - Franciscan Healthcare
9.2 out of 10, Wonderful, (511)
"Nice enough place for the night we stayed."
United States
Chris
The price is €84
includes taxes & fees
25 Jan - 26 Jan 2026
Holiday Inn Express & Suites Onalaska La Crosse Area by IHG
Indoor spa tub
Stoney Creek Hotel La Crosse - Onalaska

Stoney Creek Hotel La Crosse - Onalaska

Stoney Creek Hotel La Crosse - Onalaska
2.5 star property
8.9 km from Mayo Clinic Health System - Franciscan Healthcare
9.0 out of 10, Wonderful, (1591)
"Always enjoy staying at Stoney Creek when visiting the La Crosse area!"
United States
Josie
The price is €112
includes taxes & fees
1 Jan - 2 Jan 2026
Stoney Creek Hotel La Crosse - Onalaska
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayo Clinic Health System - Franciscan Healthcare Hotel Reviews

Home2 Suites by Hilton La Crosse

Home2 Suites by Hilton La Crosse

10/10 Excellent
"Everything was perfect, from the comfortable bed to the great breakfast. I would very much recommend this hotel. "
Michael 1-night trip
Posted 1 day ago
Home2 Suites by Hilton La Crosse

Hotels near other Mayo Clinic Health System - Franciscan Healthcare attractions

City Brewery

You can spend an afternoon exploring the galleries in City Brewery during your travels in La Crosse. Stroll along the area's riverfront or simply savour its lively bars.
See properties

St. Rose of Viterbo Convent

You can find out about the history of La Crosse with a stop at St. Rose of Viterbo Convent. Wander the area's riverfront or simply enjoy one of its lively bars.
See properties

Frequently asked questions

What's the area like around Mayo Clinic Health System - Franciscan Healthcare?
Mayo Clinic Health System - Franciscan Healthcare is located in La Crosse. If you're looking for a convenient place to stay, take a look at the 33 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Mayo Clinic Health System - Franciscan Healthcare?
Gundersen Hotel & Suites is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.6 mi (1 km) from Mayo Clinic Health System - Franciscan Healthcare. Other good options within a short distance include Radisson Hotel La Crosse and The Charmant Hotel.
How many hotels will I be able to find near Mayo Clinic Health System - Franciscan Healthcare?
Expedia has 33 hotels and other accommodation options within a mile from Mayo Clinic Health System - Franciscan Healthcare.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Health System - Franciscan Healthcare, will I receive a refund?
Yes, the majority of hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to view the top deals on offer near Mayo Clinic Health System - Franciscan Healthcare.
What can I see and do near Mayo Clinic Health System - Franciscan Healthcare?
You'll want to browse the exhibits at Swarthout Museum and Dahl Auto Museum. Consider spending a leisurely afternoon outside at Riverside Park, Grandad Bluff Park or Goose Island County Park. Lounge by the water at Pettibone Beach and Black River Beach.