A historic building with a dome and columns, surrounded by trees and benches.

Mesagne Hotel Guide - Hotels with Spa in Mesagne, Puglia

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Mesagne Hotels with Spa

Tonight
13 Oct - 14 Oct
Tomorrow
14 Oct - 15 Oct
This weekend
16 Oct - 18 Oct
Next weekend
23 Oct - 25 Oct

Our top choices for Mesagne hotels with a spa

A modern indoor pool area with a glass wall, white lounge chairs, and a visible sauna area.
An indoor dining area with tables and chairs, large windows, and potted plants.
A pool with a clear view through a woven arch, surrounded by lounge chairs and a white building in the background.
A restaurant with white tables and chairs, large windows, and hanging light fixtures.

1. Masseria Elysium

Masseria Elysium
Mesagne
  • Rejuvenate at this Mediterranean farm stay offering indulgent spa services, a hot tub, and a sauna amid serene garden landscapes.
€108
includes taxes & fees
16 Oct - 17 Oct
Masseria Elysium
Indoor spa tub
Hallway
Property amenity
Interior

2. Tenuta Moreno

Tenuta Moreno
Mesagne
  • Relax and rejuvenate at this Beaux Arts hotel with a full-service spa offering aromatherapy and Ayurvedic treatments.
€122
includes taxes & fees
17 Oct - 18 Oct
Tenuta Moreno
A modern interior with a glass-enclosed shower, a seating area with candles, and a wooden floor.
A well-lit outdoor lounge area with lounge chairs, umbrellas, and a wooden ceiling.
A beach scene with a thatched roof structure, white lounge chairs, and a red boat labeled "SAINT FRANCOIS" in the water.
A bedroom with a large bed, white bedding, and a canopy.

3. Masseria Messapia Wine Resort & SPA

Masseria Messapia Wine Resort & SPA
Mesagne
  • Luxurious Turkish bath and deep-tissue massages await at this winery resort with private beach access.
€199
includes taxes & fees
18 Oct - 19 Oct
Masseria Messapia Wine Resort & SPA
A modern bathroom with a large bathtub, a wooden vanity, and a seating area with a bench and cushions.
A hot tub with water bubbling, a wooden cabinet, a potted plant, and a doorway leading to another room.
A modern living room with a wooden bench, a small table, and a sofa. There is a wooden cabinet with a glass door and a potted plant.
A modern living room with a curved sofa, a blue armchair, and a wooden cabinet.

4. Centrale Suites

Centrale Suites
Brindisi Historic Center
€75
includes taxes & fees
1 Nov - 2 Nov
Centrale Suites
A person lying on a massage table with a view of a pool and outdoor seating.
A stone building with a sign reading "RISTORANTE" and a bench in front.
A restaurant with stone walls, wooden tables, and a fireplace.
A stone building with arched windows and a covered outdoor seating area.

5. Tenute Al Bano

Tenute Al Bano
Cellino San Marco
  • Enjoy rejuvenating treatments at this rural retreat with couples spa rooms, an outdoor pool, and an attached winery for a complete escape.
€132
includes taxes & fees
27 Oct - 28 Oct
Tenute Al Bano
A spa room with a sauna, a glass-enclosed shower, and a wooden bench.
A spacious room with a large oval bathtub, a wooden chair, a small table, and a view of the outdoors through a window.
A bedroom with a stone fireplace, a large bathtub, and a bed with green bedding.
A swimming pool with a metal ladder, surrounded by lush greenery and tall trees under a partly cloudy sky.

6. Villa Neviera - Wine Resort and Spa

Villa Neviera - Wine Resort and Spa
San Donaci
  • Unwind in a full-service spa villa nestled within a wine resort, where garden views and vineyard experiences create a restorative retreat.
€79
includes taxes & fees
1 Nov - 2 Nov
Villa Neviera - Wine Resort and Spa
A sauna with wooden walls and a bench.
A modern bathroom with a glass-enclosed shower, a bathtub with green water, and a large mirror.
A kitchen with white walls, a stone accent wall, a wooden table with a bowl of fruit, a bottle, and a cup. There are two white chairs and a hanging light fixture.
A bedroom with a bed, a mirror, a ladder, and a glass door leading to a bathroom.

7. FILIA SOLIS - Old Town SUITEs & SPA

FILIA SOLIS - Old Town SUITEs & SPA
Brindisi Historic Center
  • Relax in the heart of Old Town Brindisi with private hot tubs and luxurious massages at this spa-focused aparthotel retreat.
€123
includes taxes & fees
1 Nov - 2 Nov
FILIA SOLIS - Old Town SUITEs & SPA
A reception area with a wooden counter, a round mirror, and a chandelier.
A modern bathroom with a bathtub, a sink, and a mirror. There are shelves with toiletries and a towel rack.
A modern bedroom with a large bed, a desk, and a shower area.
A modern indoor pool with a water feature, arched ceilings, and a reception area visible through an archway.

8. Dimora Nettare

Dimora Nettare
Brindisi Historic Center
  • Soothe away stress at this rejuvenating affittacamere featuring Swedish, Thai, and hot stone massages near Port of Brindisi.
€104
includes taxes & fees
14 Oct - 15 Oct
Dimora Nettare
A restaurant with a long table layout, wooden beams, and a view through an arched window.
A building with a white facade, an arched entrance, and a garden with various plants and flowers.
A rooftop deck with outdoor seating and a pool.
A bedroom with a four-poster bed, stone walls, and a wooden ceiling beam.

9. Le Scuderie - Castello Monaci

Le Scuderie - Castello Monaci
Salice Salentino
  • Serene spa getaway with Turkish bath, couples massage rooms, and seasonal outdoor pool for relaxation.
€144
includes taxes & fees
25 Oct - 26 Oct
Le Scuderie - Castello Monaci
A spacious room with a pool, a table with a floral tablecloth, and a red accent wall.
A hallway with a red wall, a tiled floor, a wicker sofa, a small table with a lamp, and a decorative rug.
A spacious living area with a high arched ceiling, a dining table with chairs, a sofa, and a small side table with a lamp.
A bedroom with a large arched stone ceiling, a wooden bed, two smaller beds, a red chair, and a patterned rug.

10. Laurito Resort & Spa

Laurito Resort & Spa
Oria
  • Indulge in restorative treatments at this spa retreat with indoor pool, sauna, and dedicated couples rooms for relaxation.
€135
includes taxes & fees
14 Oct - 15 Oct
Laurito Resort & Spa
View all properties

Choose what matters most at spa hotels in Mesagne

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Mesagne Hotel Reviews

Ostuni a Mare

Ostuni a Mare

10/10 Excellent
"This was a definite WOW! The place is beautifully designed in and out. Always impeccably clean! Very comfortable and spacious room, breakfast is delicious as well as the lunch and evening meals, wine list and bar menu. Best of all the staff is simply amazing!! From reception to restaurant to beach and cleaning ladies. We meet so many wonderful, helpful and always smiling people. Sonia, Rosa, Pamela, Giovanni, Antonio, Angela and so many more, thank you for just a fabulous time at Ostuni A Mare! Puglia is beautiful! Highly recommend!!"
Maria 9-night trip
Posted 22 hours ago
Ostuni a Mare
Hotel Orientale

Hotel Orientale

10/10 Excellent
"Fabulous! Had a lovely stay in a great location. Staff were brilliant"
Steven 7-night trip
Posted 6 days ago
Hotel Orientale
Le Dune Suite Hotel

Le Dune Suite Hotel

10/10 Excellent
"A bit out of the way and surrounding area isnt the nicest but one of the nicest beaches in Italy so far. Hotel is nice, well maintained, great staff. Excellent breakfast, easy parking and the sunsets from the beach bar are outstanding!"
Penny 1-night trip
Posted 9 days ago
Le Dune Suite Hotel
Ostuni Palace Hotel Ristorante & SPA

Ostuni Palace Hotel Ristorante & SPA

10/10 Excellent
"We really enjoyed our stay at Ostuni Palace Hotel Ristorante & Spa. The location was fantastic, with beautiful views of Ostuni right outside the hotel and only about a 10-minute walk to the historic centre. Our room was very clean and spacious, and the bathroom was surprisingly large, which was a nice bonus. The hotel itself is beautiful and well maintained, and breakfast was very good with a great selection. Another big plus was the free parking, which made having a car in Ostuni so much easier. Breakfast and parking being included made the stay even better value. We didn’t get a chance to try the spa during our stay, but it’s a nice option to have on-site. Overall, a beautiful hotel in a great location for exploring Ostuni."
Teresa 2-night trip
Posted 3 weeks ago
Ostuni Palace Hotel Ristorante & SPA
Tenuta Moreno

Tenuta Moreno

10/10 Excellent
"My Sons Wedding. Perfect in all ways. Super helpful staff, lovely, clean rooms, Outstanding food, Young man on the bar was brilliant, well kept grounds and pool area, Thank you! A beautiful experience for all our family."
John Richard 3-night trip
Posted 1 month ago
Tenuta Moreno

Frequently asked questions

Looking to holiday at a spa hotel in Mesagne?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Enjoy the historical sites and restaurants in Mesagne—your day trip starts here. Take in the culture at the monuments and museums during your stay. Spa hotels are a great way to break out of your routine and add a layer of luxury to your stay.
What is the best spa hotel in Mesagne?
Tenuta Moreno is a top spa hotel featuring a rooftop terrace, a fitness centre, tennis courts and a bar. Enjoy a facial, body scrub or thalassotherapy at the on-site spa. Another popular spa hotel in Mesagne is Masseria Messapia Wine Resort & SPA.
How many spa hotels are there in Mesagne?
Among Expedia's 84 accommodation options in Mesagne, there are 3 spa hotels.
What's there to see and do in Mesagne?
Enjoy all that Mesagne has to offer and visit Mesagne Castle, Teatro Comunale di Mesagne and Piazza Orsini del Balzo. If you have some spare time during your trip, you might want to check out Court of Brindisi and Carrisiland Resort.
What is a Mesagne spa hotel?
Spa hotels in Mesagne provide lodging and have a full on-site spa which offers services such as massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.