North Main Street Historic District
Visit North Main Street Historic District
Popular places to visit

Lake Wappapello State Park
You can take time to visit Lake Wappapello State Park during your travels to Wappapello.

Lake Wappapello
Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.
Margaret Harwell Art Museum
You can study the exhibits at Margaret Harwell Art Museum, a museum with a storied past, during your trip to Poplar Bluff. Stroll along the riverfront or experience the entertainment choices in this family-friendly area.
Mo-Ark Regional Railroad Museum
You can study the exhibits at Mo-Ark Regional Railroad Museum, a museum with a storied past, during your holiday in Poplar Bluff. While in this family-friendly area, you can enjoy the restaurants.
Black River Coliseum
Catch an event at Black River Coliseum during your trip to Poplar Bluff. While in this family-friendly area, you can enjoy the restaurants.
Ozark Ridge Golf Course
Enjoy a round of golf in Poplar Bluff at Ozark Ridge Golf Course. Take in the entertainment choices and waterfalls in the area.
Top Hotel Deals
Check availability on hotels close to North Main Street Historic District

Drury Inn & Suites Poplar Bluff

Holiday Inn Poplar Bluff by IHG

Hampton Inn Poplar Bluff

Motel 6 Poplar Bluff, MO

Super 8 by Wyndham Poplar Bluff Missouri

Historic home in the heart of Poplar Bluff

Comfort Inn Poplar Bluff North

Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff

Lake Wappapello
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- Holidays and getaways similar to North Main Street Historic District
- Hotels Near North Main Street Historic District, Poplar Bluff
- Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
- Lake Wappapello
- Waterfront Home Near Mark Twain National Forest
- SOLAR ECLIPSE! Lodge on10ac open field. 4 bed, 1 bath. Family/Pet friendly
- 40-acre Poplar Bluff Nature Lovers Paradise!
- 1/4 Mile To The Boat Launch & Beach 2 miles the Camp! Free WiFi, beautiful space
- Lake Wappapello 2 Bedroom Home 1/8 mile to beach and boat ramp
- Secluded in the woods, couple’s romantic cabin & hot tub, brkfast foods provided
- Camp Stonebass-Lake House-Hottub