Odessa Hotel Guide - Odessa Regional Medical Center hotels in Odessa, United States of America.

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
3 Mar - 4 Mar
Tomorrow
4 Mar - 5 Mar
This weekend
6 Mar - 8 Mar
Next weekend
13 Mar - 15 Mar

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Odessa Regional Medical Center hotels

Lobby

Odessa Marriott Hotel & Conference Center

Odessa Marriott Hotel & Conference Center
4.0 star property
0.2 km from Odessa Regional Medical Center
9.2 out of 10, Wonderful, (480 reviews)
"great place "
United States
Sam
The price is €175
includes taxes & fees
14 Mar - 15 Mar
Odessa Marriott Hotel & Conference Center
Terrace/patio

Holiday Inn Express & Suites Odessa I-20 by IHG

Holiday Inn Express & Suites Odessa I-20 by IHG
2.5 star property
3.1 km from Odessa Regional Medical Center
8.8 out of 10, Excellent, (485 reviews)
"The room was clean and comfortable. The staff were friendly and efficient. We enjoyed the breakfast."
United States
Holly
The price is €99
includes taxes & fees
22 Mar - 23 Mar
Holiday Inn Express & Suites Odessa I-20 by IHG
Lobby

Motel 6 Odessa, TX - 2nd Street

Motel 6 Odessa, TX - 2nd Street
2.0 star property
1.9 km from Odessa Regional Medical Center
7.8 out of 10, Good, (520 reviews)
"Clean room, nice place to lay your head after a 13 hour drive."
United States
Carson
The price is €59
includes taxes & fees
5 Mar - 6 Mar
Motel 6 Odessa, TX - 2nd Street
Lobby

MainStay Suites Odessa I-20

MainStay Suites Odessa I-20
2.5 star property
3 km from Odessa Regional Medical Center
8.2 out of 10, Very good, (311 reviews)
"Very clean very spacious rooms friendly staff loved it"
United States
Jamayea
The price is €74
includes taxes & fees
4 Apr - 5 Apr
MainStay Suites Odessa I-20
Indoor pool

SureStay Plus Hotel by Best Western Odessa

SureStay Plus Hotel by Best Western Odessa
3.0 star property
2.7 km from Odessa Regional Medical Center
7.4 out of 10, Good, (80 reviews)
"Very nice place to stay "
United States
Jerry
The price is €83
includes taxes & fees
16 Mar - 17 Mar
SureStay Plus Hotel by Best Western Odessa
Rollaway beds, free WiFi

Villa West Inn

Villa West Inn
2.0 star property
2.6 km from Odessa Regional Medical Center
7.4 out of 10, Good, (183 reviews)
"Spacious room, comfortable bed for a good nights rest. Definitely book a stay again. "
United States
Timothy
The price is €61
includes taxes & fees
16 Mar - 17 Mar
Villa West Inn
Living area

DELUX INN

DELUX INN
2.5 star property
2.5 km from Odessa Regional Medical Center
6.8 out of 10, (24 reviews)
"Best hotel "
United States
Poncho
The price is €64
includes taxes & fees
5 Mar - 6 Mar
DELUX INN
Blackout curtains, free WiFi, bed sheets

Motel 6 Odessa, TX

Motel 6 Odessa, TX
2.0 star property
2.9 km from Odessa Regional Medical Center
6.8 out of 10, (561 reviews)
"The room was very clean. And management was very helpful."
United States
Bonnie
The price is €64
includes taxes & fees
9 Mar - 10 Mar
Motel 6 Odessa, TX
Lobby sitting area

Executive Inn Odessa

Executive Inn Odessa
2.5 star property
3.2 km from Odessa Regional Medical Center
7.6 out of 10, Good, (206 reviews)
"Its a decent place to stay if you get a deal "
United States
John
The price is €54
includes taxes & fees
22 Mar - 23 Mar
Executive Inn Odessa
Seasonal outdoor pool, open 7:00 AM to 10:00 PM, pool loungers

Hawthorn Extended Stay by Wyndham Odessa

Hawthorn Extended Stay by Wyndham Odessa
3.5 star property
4.7 km from Odessa Regional Medical Center
8.6 out of 10, Excellent, (280 reviews)
"Clean room, reasonable price and restaurant on site which was perfect after a long day of driving"
United States
Kimberly
The price is €97
includes taxes & fees
6 Mar - 7 Mar
Hawthorn Extended Stay by Wyndham Odessa
BBQ/picnic Area

Staybridge Suites Odessa - Interstate HWY 20 by IHG

Staybridge Suites Odessa - Interstate HWY 20 by IHG
3.0 star property
4.5 km from Odessa Regional Medical Center
8.8 out of 10, Excellent, (152 reviews)
"Very friendly staff. "
United States
Todd
The price is €111
includes taxes & fees
3 Apr - 4 Apr
Staybridge Suites Odessa - Interstate HWY 20 by IHG
Exterior

Candlewood Suites Odessa by IHG

Candlewood Suites Odessa by IHG
2.5 star property
4.6 km from Odessa Regional Medical Center
8.6 out of 10, Excellent, (190 reviews)
"Very nice, will stay again."
United States
Marian
The price is €99
includes taxes & fees
14 Mar - 15 Mar
Candlewood Suites Odessa by IHG
Iron/ironing board, free WiFi, bed sheets

Studio 6 Odessa, TX

Studio 6 Odessa, TX
2.5 star property
4.6 km from Odessa Regional Medical Center
8.0 out of 10, Very good, (259 reviews)
"Very clean, comfortable and quiet. "
United States
Andrew
The price is €79
includes taxes & fees
9 Mar - 10 Mar
Studio 6 Odessa, TX
Exterior

Sleep Inn & Suites Odessa near University

Sleep Inn & Suites Odessa near University
2.5 star property
5.2 km from Odessa Regional Medical Center
8.6 out of 10, Excellent, (467 reviews)
"Very good"
United States
Sharmin
The price is €63
includes taxes & fees
27 Mar - 28 Mar
Sleep Inn & Suites Odessa near University
Lobby

Sonesta Essential Hotels Odessa

Sonesta Essential Hotels Odessa
2.0 star property
4.3 km from Odessa Regional Medical Center
7.8 out of 10, Good, (775 reviews)
"Nice place"
United States
Jose
The price is €59
includes taxes & fees
15 Mar - 16 Mar
Sonesta Essential Hotels Odessa
Reception

Fairfield Inn & Suites Odessa

Fairfield Inn & Suites Odessa
3.0 star property
5.3 km from Odessa Regional Medical Center
8.8 out of 10, Excellent, (417 reviews)
"Henrietta checked me in at the front desk and was so kind and friendly! Clean facilities and conveniently located ."
United States
Monica
The price is €84
includes taxes & fees
15 Mar - 16 Mar
Fairfield Inn & Suites Odessa
Premium Room, 1 King Bed, Balcony | Terrace/patio

MCM Elegante Hotel and Conference Center Odessa

MCM Elegante Hotel and Conference Center Odessa
3.5 star property
6 km from Odessa Regional Medical Center
9.0 out of 10, Wonderful, (1,007 reviews)
"Excellent stay"
United States
John
The price is €98
includes taxes & fees
13 Mar - 14 Mar
MCM Elegante Hotel and Conference Center Odessa
Reception

Hampton Inn by Hilton Odessa

Hampton Inn by Hilton Odessa
2.5 star property
5.3 km from Odessa Regional Medical Center
8.6 out of 10, Excellent, (369 reviews)
"Always a great place to stay!!!"
United States
Xavier
The price is €95
includes taxes & fees
4 Apr - 5 Apr
Hampton Inn by Hilton Odessa
BBQ/picnic Area

TownePlace Suites by Marriott Odessa

TownePlace Suites by Marriott Odessa
3.0 star property
5.6 km from Odessa Regional Medical Center
8.8 out of 10, Excellent, (515 reviews)
"Great service and breakfast was very good."
United States
Iris
The price is €97
includes taxes & fees
20 Mar - 21 Mar
TownePlace Suites by Marriott Odessa
Desk, laptop workspace, blackout curtains, iron/ironing board

Comfort Inn & Suites, Odessa I-20

Comfort Inn & Suites, Odessa I-20
2.5 star property
4.6 km from Odessa Regional Medical Center
7.8 out of 10, Good, (580 reviews)
"Room was clean and comfortable "
United States
Dolores
The price is €71
includes taxes & fees
27 Mar - 28 Mar
Comfort Inn & Suites, Odessa I-20
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Odessa Regional Medical Center Hotel Reviews

MCM Elegante Hotel and Conference Center Odessa

MCM Elegante Hotel and Conference Center Odessa

4/10 Poor
"Love the place. I have stayed there every time I come to town. Was the first time using the handicap room. Had my 80 year old friend and I think the room needs a face lift. I wasn't able to enjoy the spa but I want to book an extra day and get the works done. "
Timothy 1-night trip
Posted 3 hours ago
MCM Elegante Hotel and Conference Center Odessa

Hotels near other Odessa Regional Medical Center attractions

Odessa Jackrabbit Statue

You can learn about the history of Odessa when you stop by Odessa Jackrabbit Statue. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

White-Pool House

4.3/5 (20 reviews)
You can find out about the history of Odessa when you stop by White-Pool House. Experience the area's entertainment venues or attend a sporting event.
See properties

Frequently asked questions

What's the area like around Odessa Regional Medical Center?
Odessa Regional Medical Center is located in Odessa. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 18 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Odessa Regional Medical Center?
Adjacent to Odessa Regional Medical Center, Odessa Marriott Hotel & Conference Center is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within a few miles include MCM Grande Hotel FunDome Odessa and MCM Elegante Hotel and Conference Center Odessa.
How many hotels can I expect to find near Odessa Regional Medical Center?
Expedia has 18 hotels and other accommodation options within a mile from Odessa Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Odessa Regional Medical Center, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the best deals near Odessa Regional Medical Center.
What can I see and do near Odessa Regional Medical Center?
Study the collections at White-Pool House, Ellen Noel Art Museum or Parker House Museum. Create some family memories at Altitude Trampoline Park and Fun City. Attractions like Globe of the Great Southwest and Presidential Museum and Leadership Library highlight the local culture.