Opelousas Hotel Guide - Opelousas General Health System hotels in Opelousas, United States of America.

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Tonight
25 Dec - 26 Dec
Tomorrow
26 Dec - 27 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Opelousas General Health System hotels

Exterior
Hampton Inn Opelousas

Hampton Inn Opelousas

Hampton Inn Opelousas
2.5 star property
2.6 km from Opelousas General Health System
8.4 out of 10, Very good, (348)
"Clean room, friendly and helpful staff. Highly recommended "
United States
James
The price is €122
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Opelousas
Casino
Evangeline Downs Hotel, an Ascend Collection Hotel

Evangeline Downs Hotel, an Ascend Collection Hotel

Evangeline Downs Hotel, an Ascend Collection Hotel
3.0 star property
2.5 km from Opelousas General Health System
8.2 out of 10, Very good, (729)
"Best sleep everytime I visit love the beds "
United States
Rochelle
The price is €112
includes taxes & fees
25 Jan - 26 Jan 2026
Evangeline Downs Hotel, an Ascend Collection Hotel
Exterior
Holiday Inn Express & Suites Opelousas by IHG

Holiday Inn Express & Suites Opelousas by IHG

Holiday Inn Express & Suites Opelousas by IHG
3.0 star property
3.2 km from Opelousas General Health System
9.2 out of 10, Wonderful, (206)
"Really enjoyed the stay"
United States
Felisha
The price is €100
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express & Suites Opelousas by IHG
Outdoor pool
Hotel Klaus

Hotel Klaus

Hotel Klaus
2.0 star property
8.1 km from Opelousas General Health System
9.8 out of 10, Exceptional, (36)
"Cute Cute Cute hotel and even better staff. "
United States
Adele
The price is €134
includes taxes & fees
9 Jan - 10 Jan 2026
Hotel Klaus
Room, 1 King Bed
Spark by Hilton Opelousas

Spark by Hilton Opelousas

Spark by Hilton Opelousas
2.5 star property
3.6 km from Opelousas General Health System
7.6 out of 10, Good, (383)
"Everything looks gud great location an clean room "
United States
william
The price is €75
includes taxes & fees
11 Jan - 12 Jan 2026
Spark by Hilton Opelousas
Desk, iron/ironing board, free WiFi, bed sheets
Days Inn & Suites by Wyndham Opelousas

Days Inn & Suites by Wyndham Opelousas

Days Inn & Suites by Wyndham Opelousas
2.0 star property
3.3 km from Opelousas General Health System
6.8 out of 10, (689)
"Staff was amazing. Enjoyed my stay"
United States
Feleicia
The price is €67
includes taxes & fees
18 Jan - 19 Jan 2026
Days Inn & Suites by Wyndham Opelousas
Free WiFi, bed sheets
Motel 6 Opelousas, LA

Motel 6 Opelousas, LA

Motel 6 Opelousas, LA
2.0 star property
7.6 km from Opelousas General Health System
6.8 out of 10, (404)
"The lady at the front desk Jasmine is absolutely phenomenal!! Always so sweet and nice !!!"
United States
Ashley
The price is €57
includes taxes & fees
9 Jan - 10 Jan 2026
Motel 6 Opelousas, LA
Reception
Studio 6 Opelousas, LA

Studio 6 Opelousas, LA

Studio 6 Opelousas, LA
2.0 star property
3.3 km from Opelousas General Health System
5.6 out of 10, (261)
"The worst stay ever."
United States
Diendre
The price is €65
includes taxes & fees
9 Jan - 10 Jan 2026
Studio 6 Opelousas, LA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Opelousas General Health System Hotel Reviews

Howard Johnson by Wyndham Scott Lafayette

Howard Johnson by Wyndham Scott Lafayette

10/10 Excellent
"Have stayed here frequently. Always excellent accommodation."
Robert 1-night trip
Posted 4 days ago
Howard Johnson by Wyndham Scott Lafayette

Hotels near other Opelousas General Health System attractions

St. Landry Catholic Church

3.9/5 (13 reviews)
After visiting St. Landry Catholic Church, make a plan to see the other sights and activities in Opelousas. While in the area, you can find time to visit its casinos.
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Rural African American Museum

You can spend an afternoon exploring the galleries in Rural African American Museum during your trip to Opelousas. While in the area, you can find time to visit its casinos.
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Frequently asked questions

What's the area like around Opelousas General Health System?
Opelousas General Health System is located in Opelousas. Travellers like the surrounding area for its casinos. You'll find 15 hotels and other accommodations within a few miles for a convenient home base.
Where is the best place to stay close to Opelousas General Health System?
Evangeline Downs Hotel, an Ascend Collection Hotel is one of the top choices for your stay based on our traveller data, and this hotel offers a casino and 3 restaurants. It's located 1.6 mi (2.5 km) from Opelousas General Health System. Other good choices within a few miles include Days Inn & Suites by Wyndham Opelousas and Hampton Inn Opelousas.
How many hotels will I find near Opelousas General Health System?
Expedia has 15 hotels and other accommodation options a few miles from Opelousas General Health System.
If I need to cancel the hotel reservation for my stay near Opelousas General Health System, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might be able to still cancel and get a refund within 24 hours of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to review the best deals available near Opelousas General Health System.