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Residence Inn Durham McPherson/Duke University Medical Cntr

3.0 star property
Hotel with free breakfast, 5-minute walk to Duke University

Choose dates to view prices

Residence Inn Durham McPherson/Duke University Medical Center offers a refreshed retreat with practical comforts. Enjoy a to-go breakfast, relax by the lobby fireplace, and request complimentary grocery shopping. WiFi in all rooms and an area shuttle make attractions accessible.

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Pet-friendly
  • Free Wi-Fi
  • Air-conditioning
  • Parking available
The current price is €135
includes taxes & fees
19 Dec - 20 Dec

Room options

Available filters for rooms
Showing 10 of 10 rooms

View all photos for Suite, 1 Bedroom

32-inch Smart TV with cable channels, TV, Netflix

Suite, 1 Bedroom

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 44 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Studio, 1 King Bed with Sofa bed

In-room safe, desk, laptop workspace, blackout curtains

Studio, 1 King Bed with Sofa bed

8.8 out of 10
Excellent
(32 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 45 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 Queen Bed with Sofa bed

In-room safe, desk, laptop workspace, blackout curtains

Studio, 1 Queen Bed with Sofa bed

9.6 out of 10
Exceptional
(14 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 39 sq m
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout curtains

Suite, 1 Bedroom (Hearing Accessible)

8.8 out of 10
Excellent
(3 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

View all photos for Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

In-room safe, desk, laptop workspace, blackout curtains

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

10.0 out of 10
Exceptional
(1 review)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 44 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

In-room safe, desk, laptop workspace, blackout curtains

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 45 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 King Bed with Sofa bed (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout curtains

Studio, 1 King Bed with Sofa bed (Hearing Accessible)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 45 sq m
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

In-room safe, desk, laptop workspace, blackout curtains

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • 40 sq m
  • Sleeps 3
  • 1 Queen Bed and 1 Double Sofa Bed

View all photos for Suite, Multiple Beds (Mobility Accessible, Tub)

Suite, Multiple Beds (Mobility Accessible, Tub)

Suite, Multiple Beds (Mobility Accessible, Tub)

8.0 out of 10
Very good
(2 reviews)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed

View all photos for Suite, 1 Bedroom (Mobility Accessible, Roll-in Shower)

In-room safe, desk, laptop workspace, blackout curtains

Suite, 1 Bedroom (Mobility Accessible, Roll-in Shower)

10.0 out of 10
Exceptional
(1 review)

Highlights

Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed OR 1 Queen Bed

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About the area

Map
1108 West Main Street, Durham, NC, 27701

What's nearby

  • Brightleaf Square - 3 min walk - 0.3 km
  • Duke University - 3 min walk - 0.3 km
  • Durham Convention Center - 12 min walk - 1.1 km
  • Carolina Theatre - 12 min walk - 1.1 km
  • Durham Performing Arts Center - 17 min walk - 1.4 km

Getting around

  • Durham Station - 8 min walk
  • Raleigh-Durham International Airport (RDU) - 19 min drive

Restaurants

  • ‪The Can Opener - ‬7 min walk
  • ‪Ramblers - ‬7 min walk
  • ‪Emmy Squared - ‬5 min walk
  • ‪The Federal - ‬3 min walk
  • ‪Fonda Lupita - ‬3 min walk

About this property

Residence Inn Durham McPherson/Duke University Medical Cntr

Hotel remodelled in 2024 and located near Duke University
Consider a stay at Residence Inn Durham McPherson/Duke University Medical Cntr and take advantage of free on-the-go breakfast, a free food/drink shopping service and a terrace. In addition to dry cleaning/laundry services and a fireplace in reception, guests can connect to free in-room WiFi.
Other perks include:
  • A free local area shuttle, self-parking (surcharge) and express check-out
  • Express check-in, a computer station and coffee/tea in reception
  • Free newspapers, laundry services and a banquet hall
  • Guest reviews say great things about the helpful staff
Room features
All 147 rooms include comforts such as laptop-friendly workspaces and air conditioning, in addition to thoughtful touches such as free WiFi and desk chairs.
More conveniences in all rooms include:
  • Recycling and LED light bulbs
  • Shower/bath combinations, free toiletries and hairdryers
  • 32-inch Smart TVs with Netflix and premium channels
  • Wardrobes/cupboards, separate sitting areas and kitchens

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  • Free Wi-Fi
  • Air-conditioning
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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Free area shuttle
  • Parking on site (USD 15 per day)
  • Wheelchair-accessible parking available

Food and drink

  • Free on-the-go breakfast available daily 7:00 AM to 9:00 AM
  • A bar/lounge
  • Coffee and tea in common areas

Things to do

  • 24-hour gym

Family friendly

  • Dining table
  • Free area shuttle
  • Grocery/convenience store
  • In-room full-sized refrigerator/freezer
  • In-room kitchen
  • In-room microwave
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Wedding services

Business services

  • 2,530 square feet of conference space
  • Business centre
  • Computer station

Outdoors

  • Terrace

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • 7 accessible parking spaces
  • Assistive listening devices in meeting rooms
  • Braille/raised signage
  • Hardwood flooring in room
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Thin carpet in room
  • Visual alarms in hallways
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business centre
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible registration desk (86 centimetre high)
  • Wheelchair-accessible restaurant

More

  • 5 floors
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Built in 2015
  • Comprehensive recycling policy
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • No plastic drinking straws
  • Renovated entire property - April 2024
  • Smoke-free property
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Free toiletries
  • Hair dryer
  • Shower/bathtub combination
  • Towels provided

Entertainment

  • 32-inch smart TV with premium cable channels
  • Netflix
  • Pay films

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dining table
  • Dishwasher
  • Full-sized refrigerator/freezer
  • Hob
  • Kitchen
  • Microwave

More

  • Air conditioning (climate-controlled)
  • Desk
  • Desk chair
  • Energy-saving switches in guestrooms
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • LED lighting
  • Phone
  • Recycling
  • Safe
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 3 PM; check-in end time: midnight
Express check-in available
Minimum check-in age - 21

Check-out

Check-out before noon
Contactless check-out
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets are allowed for an extra charge of USD 100.00 per pet (varies based on length of stay)
Service animals are welcome, and are exempt from fees
2 total (up to 45 kg per pet)
Restrictions apply; for more information contact the property on the number on the booking confirmation

Children and extra beds

Children are welcome
Rollaway/extra beds are not available.
Cots (infant beds) are not available

Payment types at the property

Important information

Optional extras

  • Self-parking fee: USD 15 per day
  • Pet fee: USD 100.00 per pet (varies based on length of stay)
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.

We should mention

Guests under 18 years old are not allowed in the fitness facility, and guests under 18 years old are only allowed in the swimming pool and fitness facility with adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn Durham McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr

Frequently asked questions

Is Residence Inn Durham McPherson/Duke University Medical Cntr pet-friendly?

Yes, Residence Inn Durham McPherson/Duke University Medical Cntr allows pets (limit 2 total) with a maximum weight of up to 45 kg per pet. There's a fee of USD 100.00 per pet, per stay. Service animals are exempt from fees. Some restrictions may apply, so please contact the property for more details.

How much does it cost to stay at Residence Inn Durham McPherson/Duke University Medical Cntr?

As of 16 Dec 2025, prices found for a 1-night stay for 2 adults at Residence Inn Durham McPherson/Duke University Medical Cntr on 19 Dec 2025 start from €135.10, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

How much is parking at Residence Inn Durham McPherson/Duke University Medical Cntr?

Self-parking is available for USD 15 per day.

What time is check-in at Residence Inn Durham McPherson/Duke University Medical Cntr?

Check-in start time: 3 PM; check-in end time: midnight.

What time is check-out at Residence Inn Durham McPherson/Duke University Medical Cntr?

Checkout is at noon.

Where is Residence Inn Durham McPherson/Duke University Medical Cntr located?

Located in Downtown Durham, this hotel is within a 10-minute walk of Brightleaf Square and Duke University. Carolina Theatre and Durham Convention Center are also within 15 minutes. Durham Station is 8 minutes by foot.

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Reviews

Residence Inn Durham McPherson/Duke University Medical Cntr Reviews

9.2

Wonderful

9.4

Cleanliness

9.0

Location

9.4

Staff & service

9.0

Eco-friendliness

9.4

Property conditions & facilities
Rating 10 - Excellent. 312 out of 459 reviews
Rating 8 - Good. 104 out of 459 reviews
Rating 6 - Okay. 27 out of 459 reviews
Rating 4 - Poor. 6 out of 459 reviews
Rating 2 - Terrible. 10 out of 459 reviews

Reviews

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Hotel was great - very friendly staff.
Stayed 2 nights in Sep 2025

8/10 Good

James

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice hotel for the price. Good location. Big rooms. Quiet. Easy parking. Could be a little cleaner.
Stayed 2 nights in Oct 2025

8/10 Good

nicole

Liked: Cleanliness, staff & service, property conditions & facilities
Clean room. Lighting in bathroom needs to be better.
Stayed 1 night in Oct 2025

10/10 Excellent

Derek

Liked: Cleanliness, staff & service, property conditions & facilities
Was very nice. The staff was very polite when we arrived.
Stayed 1 night in Aug 2025

10/10 Excellent

Anthony

Liked: Amenities
Yes
Stayed 4 nights in Sep 2025

8/10 Good

Heman

Liked: Cleanliness, amenities, property conditions & facilities
Laura and Tiffany were extremely helpful and accommodating. The whole staff was very friendly and welcoming!
Stayed 9 nights in Jul 2025

8/10 Good

Maria

Liked: Cleanliness, staff & service, amenities
Great location! You can walk to great restaurants and coffee shops. The room is clean and spacious. The bed is very comfortable and it felt like a nice treat at the end of long day. The staff is very friendly, specially Tiffani and Laura at the reception desk. They were very helpful and welcoming, always greeting you with a big smile and making sure we were doing fine. I will definitely stay there on my next visit.
Stayed 7 nights in Aug 2025

8/10 Good

Minor

Liked: Cleanliness, staff & service
An excellent place to stay!
Stayed 1 night in Feb 2025

10/10 Excellent

LaMeesha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
I am thankful for the very hospitable staff that I encountered at the hotel. Everyone was smiling at the front desk every time I passed by.
Stayed 8 nights in Jun 2025

10/10 Excellent

Timmy

Liked: Cleanliness, amenities, property conditions & facilities
It was very clean and the staff was excellent. The stay was really good. The attendant was great at checking.
Stayed 1 night in Jun 2025

10/10 Excellent

Melissa

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Staff was amazing! Breakfast had so many options, quiche, waffles, fresh fruit, sausage, hard boiled eggs…. Room was very clean. Small market store in lobby. Lobby area with a tv and tons of seating. Nice workout room. But again, staff was incredible!
Stayed 8 nights in Jul 2025

10/10 Excellent

Kaiqing

Liked: Cleanliness, staff & service, property conditions & facilities
All good as expected
Stayed 14 nights in Jul 2025

10/10 Excellent

Ronnie A.

Liked: Cleanliness, staff & service, property conditions & facilities
We had an issue with the room but the district manager took care of it immediately. Excellent Team
Stayed 8 nights in Jul 2025

10/10 Excellent

David

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We love staying here when we come to visit our family. Every stay has been wonderful. The room is very comfortable. We love the gym and the breakfasts. Having a nice laundry area on the premises is also a huge plus. The best part is the fantastic staff-everyone is so nice and helpful. Thank you for always making our trips memorable.
Stayed 7 nights in May 2025

10/10 Excellent

Reed

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The place to stay if you have business at Duke. Housekeeping is hit-or-miss, but that's par for the course for an extended-stay hotel.
Stayed 6 nights in Apr 2025

10/10 Excellent

Judy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great location with some incredible Restaurants nearby
Stayed 3 nights in Oct 2024

10/10 Excellent

Hong

Liked: Cleanliness, staff & service, property conditions & facilities
Nice staff, very helpful. Close to Duke University, great place to stay.
Stayed 6 nights in Jan 2025

10/10 Excellent

Margaret

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great and reasonably priced place to stay as a family in the center of Durham.
Stayed 1 night in Sep 2024

10/10 Excellent

Wendy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, friendly, great location.
Stayed 1 night in Sep 2024

8/10 Good

Robert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Shoutout to Tiffany/Stephanie? on front desk duty - she greeted us with a warm welcome & useful information!
Stayed 1 night in May 2025

10/10 Excellent

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great value, good location, decent breakfast

Clean, walking distance to gas stations and restaurants.,, decent breakfast in the morning that was free so can't complain... free hot coffee all day... spacious and well-decorated rooms with good cable and smart tvs. All around, great value for the price
Stayed 2 nights in Jan 2025

10/10 Excellent

Jo Anne

Liked: Cleanliness, staff & service, property conditions & facilities
Great place
Stayed 2 nights in May 2024

10/10 Excellent

Christopher

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great place!
Stayed 3 nights in Dec 2023

8/10 Good

PRAVEEN

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Good place to stay ...convenient to walk to Duke

The check in was super nice. The air conditioner was making a lot of noise - a racket. We had to complain multiple times. But they did respond 🙄 after the third vociferous complaint and replaced compressor. Friendly maintainence team , Barry the maintainence executive brought in a lot of smiles with his attitude.
Stayed 14 nights in Jun 2025

10/10 Excellent

Jackson

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice clean room,good breakfast and great staff.
Stayed 4 nights in Nov 2022