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Residence Inn Durham McPherson/Duke University Medical Center offers a refreshed retreat with practical comforts. Enjoy a to-go breakfast, relax by the lobby fireplace, and request complimentary grocery shopping. WiFi in all rooms and an area shuttle make attractions accessible.
Reviews
9.2 out of 10
Wonderful
Popular amenities
The current price is €152
includes taxes & fees
28 Sept - 29 Sept
Room options
Check availability for these dates
Available filters for rooms
Showing 10 of 10 rooms
View all photos for Suite, 1 Bedroom

Suite, 1 Bedroom
9.2 out of 10
Wonderful
(5 reviews)
Highlights
Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
View all photos for Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)

Studio, 1 King Bed with Sofa bed (Mobility/Hearing Accessible, Tub)
Highlights
Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
View all photos for Studio, 1 King Bed with Sofa bed, Non Smoking

Studio, 1 King Bed with Sofa bed, Non Smoking
8.8 out of 10
Excellent
(31 reviews)
Highlights
Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
View all photos for Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

Studio, 1 King Bed with Sofa bed (Mobility Accessible, Tub)
Highlights
Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
View all photos for Suite, 1 Bedroom, Non Smoking (Hearing Accessible)

Suite, 1 Bedroom, Non Smoking (Hearing Accessible)
10.0 out of 10
Exceptional
(2 reviews)
Highlights
Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
View all photos for Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)

Suite, Multiple Beds, Non Smoking (Mobility Accessible, Tub)
Highlights
Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
View all photos for Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)

Suite, 1 Bedroom, Non Smoking (Mobility Accessible, Roll-in Shower)
10.0 out of 10
Exceptional
(1 review)
Highlights
Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
View all photos for Studio, 1 King Bed with Sofa bed (Hearing Accessible)

Studio, 1 King Bed with Sofa bed (Hearing Accessible)
Highlights
Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
View all photos for Studio, 1 Queen Bed with Sofa bed, Non Smoking

Studio, 1 Queen Bed with Sofa bed, Non Smoking
9.6 out of 10
Exceptional
(14 reviews)
Highlights
Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
View all photos for Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)

Studio, 1 Queen Bed with Sofa bed (Hearing Accessible)
Highlights
Separate sitting area
Air conditioning
Kitchen
Full-sized fridge/freezer
Dining table
Dishwasher
Smart TV
Renovated in 2024
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The price is €151
includes taxes & fees
28 Sept - 29 Sept
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About the area

1108 West Main Street, Durham, NC, 27701
About this property
Residence Inn Durham McPherson/Duke University Medical Cntr
Property amenities
Room amenities
Policies
Important information
Optional extras
- Self-parking fee: USD 15 per day
- Pet fee: USD 100.00 per pet (varies based on length of stay)
- Service animals are exempt from fees
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector and a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.
We should mention
Guests under 18 years old are not allowed in the fitness facility, and guests under 18 years old are only allowed in the swimming pool and fitness facility with adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)
Property is also known as
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn Durham McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr Hotel
Residence Inn McPherson/Duke University Medical Cntr
Frequently asked questions
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Reviews
Residence Inn Durham McPherson/Duke University Medical Cntr Reviews
9.2
Wonderful
9.4
Cleanliness
9.0
Location
9.4
Staff & service
9.0
Eco-friendliness
9.4
Property conditions & facilities
Reviews
5 Aug 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Aug 2025
8/10 Good
Maria
19 Aug 2025
Liked: Cleanliness, staff & service, amenities
Maria
Stayed 7 nights in Aug 2025
8/10 Good
Heman
18 Jul 2025
Liked: Cleanliness, amenities, property conditions & facilities
Heman
Stayed 9 nights in Jul 2025
10/10 Excellent
Melissa
29 Jul 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Melissa
Stayed 8 nights in Jul 2025
10/10 Excellent
LaMeesha
26 Jun 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
LaMeesha
Stayed 8 nights in Jun 2025
10/10 Excellent
Ronnie A.
26 Jul 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Ronnie A.
Stayed 8 nights in Jul 2025
10/10 Excellent
Kaiqing
19 Jul 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Kaiqing
Stayed 14 nights in Jul 2025
10/10 Excellent
Timmy
9 Jun 2025
Liked: Cleanliness, amenities, property conditions & facilities
Timmy
Stayed 1 night in Jun 2025
8/10 Good
Minor
2 Feb 2025
Liked: Cleanliness, staff & service
Minor
Stayed 1 night in Feb 2025
10/10 Excellent
David
31 May 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
David
Stayed 7 nights in May 2025
10/10 Excellent
Reed
10 May 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Reed
Stayed 6 nights in Apr 2025
8/10 Good
Robert
21 May 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Robert
Stayed 1 night in May 2025
10/10 Excellent
Judy
2 Nov 2024
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Judy
Stayed 3 nights in Oct 2024
10/10 Excellent
Hong
3 Feb 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Hong
Stayed 6 nights in Jan 2025
6/10 Okay
Tian
30 May 2025
Disliked: Staff & service, amenities
Tian
Stayed 1 night in May 2025
10/10 Excellent
Margaret
27 Sept 2024
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Margaret
Stayed 1 night in Sep 2024
10/10 Excellent
Verified traveller
7 Feb 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great value, good location, decent breakfast
Verified traveller
Stayed 2 nights in Jan 2025
10/10 Excellent
Wendy
19 Sept 2024
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wendy
Stayed 1 night in Sep 2024
10/10 Excellent
Swarup
23 Dec 2024
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Swarup
Stayed 1 night in Dec 2024
10/10 Excellent
Jo Anne
7 May 2024
Liked: Cleanliness, staff & service, property conditions & facilities
Jo Anne
Stayed 2 nights in May 2024
10/10 Excellent
Christopher
30 Jan 2024
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Christopher
Stayed 3 nights in Dec 2023
10/10 Excellent
Cynthia
31 Dec 2024
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Loved Tiffani. Beautiful facility.
Cynthia
Stayed 1 night in Dec 2024
4/10 Poor
zubina
26 Aug 2024
Disliked: Amenities, property conditions & facilities
zubina
Stayed 2 nights in Aug 2024
10/10 Excellent
eric
28 Oct 2024
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
The place to stay!!
eric
Stayed 2 nights in Oct 2024
10/10 Excellent
Lalita
3 Sept 2024
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Excellent
Lalita
Stayed 3 nights in Aug 2024