San Antonio Hotel Guide. Hotels in Medical Center District, San Antonio, United States of America

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Our top choices for Medical Center District hotels

San Antonio Marriott Northwest Medical Center

San Antonio Marriott Northwest Medical Center
3.5 star property
Medical Center District
8.6 out of 10, Excellent, (1,001 reviews)
"Perfect place to stay comfy and clean delicious food good staff thank you much."
United States
Iris Grisell
The price is €103
includes taxes & fees
22 Mar - 23 Mar
San Antonio Marriott Northwest Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center

Fairfield Inn & Suites by Marriott San Antonio Medical Center
3.0 star property
Medical Center District
9.0 out of 10, Wonderful, (1,001 reviews)
"clean room staff was very friendly, breakfast was amazing!!"
United States
Drew
The price is €90
includes taxes & fees
5 Apr - 6 Apr
Fairfield Inn & Suites by Marriott San Antonio Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center

Drury Inn & Suites San Antonio Northwest Medical Center
3.0 star property
Medical Center District
9.2 out of 10, Wonderful, (1,275 reviews)
"We had a great stay! Staff was always helpful, room was clean. "
United States
Raymalyn
The price is €92
includes taxes & fees
25 Mar - 26 Mar
Drury Inn & Suites San Antonio Northwest Medical Center

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
3.0 star property
Medical Center District
8.4 out of 10, Very good, (3,211 reviews)
"Nice, clean, quiet, easy, quick check in and check out, nice pool and hot tub"
United States
donald
The price is €91
includes taxes & fees
18 Mar - 19 Mar
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Courtyard by Marriott Medical Center San Antonio

Courtyard by Marriott Medical Center San Antonio
3.0 star property
Medical Center District
8.8 out of 10, Excellent, (1,002 reviews)
"It is an older property but clean and very close to our doctors appt. "
United States
Melissa
The price is €86
includes taxes & fees
29 Mar - 30 Mar
Courtyard by Marriott Medical Center San Antonio

Studio 6 San Antonio, Tx - Northwest Medical Center

Studio 6 San Antonio, Tx - Northwest Medical Center
2.0 star property
Medical Center District
7.4 out of 10, Good, (257 reviews)
"This Hotel is well lit and we felt safe. The staff was outstanding during check in and check out! Room was very clean. We had a very comfortable stay. "
United States
Gilbert
The price is €47
includes taxes & fees
23 Mar - 24 Mar
Studio 6 San Antonio, Tx - Northwest Medical Center

OYO Inn & Suites Medical Center San Antonio

OYO Inn & Suites Medical Center San Antonio
2.0 star property
Medical Center District
7.2 out of 10, Good, (229 reviews)
"Staff was courteous and professional and the room is nice."
United States
Thomas
The price is €70
includes taxes & fees
15 Mar - 16 Mar
OYO Inn & Suites Medical Center San Antonio

Park Inn by Radisson

Park Inn by Radisson
2.0 star property
Medical Center District
7.2 out of 10, Good, (1,000 reviews)
"Room was spotless and bed was great."
United States
Pamela
The price is €64
includes taxes & fees
12 Apr - 13 Apr
Park Inn by Radisson

Flex Studios

Flex Studios
2.5 star property
Medical Center District
6.0 out of 10, (512 reviews)
"It was a comfortable stay. No roaches or bed bugs at affordable prices "
United States
FrankR
The price is €41
includes taxes & fees
15 Mar - 16 Mar
Flex Studios

Atria Inn & Suites

Atria Inn & Suites
2.0 star property
Medical Center District
7.6 out of 10, Good, (284 reviews)
"Room was good standings, staff was friendly "
United States
Luis
Atria Inn & Suites

Motel 6 San Antonio, TX - Northwest Medical Center

Motel 6 San Antonio, TX - Northwest Medical Center
2.0 star property
Medical Center District
6.0 out of 10, (999 reviews)
"Room was clean, beds comfortable, staff extremely friendly and helpful "
United States
Kathleen
The price is €49
includes taxes & fees
26 Mar - 27 Mar
Motel 6 San Antonio, TX - Northwest Medical Center

Studio 6 San Antonio, TX - Medical Center

Studio 6 San Antonio, TX - Medical Center
2.0 star property
Medical Center District
6.8 out of 10, (838 reviews)
"Staff was great, very clean rooom"
United States
Laura
The price is €45
includes taxes & fees
26 Mar - 27 Mar
Studio 6 San Antonio, TX - Medical Center

Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Country Inn & Suites by Radisson, San Antonio Medical Center, TX
3.0 star property
Medical Center District
6.8 out of 10, (1,004 reviews)
"Great place , front desk are helpful and friendly. Safe place to stay ."
United States
Justin
The price is €63
includes taxes & fees
22 Mar - 23 Mar
Country Inn & Suites by Radisson, San Antonio Medical Center, TX

Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Hyatt Vacation Club at Wild Oak Ranch, San Antonio
3.5 star property
Far West Side, 11.3 km from Medical Center District
9.0 out of 10, Wonderful, (1,505 reviews)
"Great place"
United States
Jonatan
The price is €125
includes taxes & fees
12 Apr - 13 Apr
Hyatt Vacation Club at Wild Oak Ranch, San Antonio

Plaza San Antonio Hotel & Spa, Autograph Collection

Plaza San Antonio Hotel & Spa, Autograph Collection
4.0 star property
Downtown San Antonio, 12.9 km from Medical Center District
9.4 out of 10, Exceptional, (747 reviews)
"absolutely gorgeous place to stay at if your in san antonio this is definitely the spot to be at 😁"
United States
Joangel
The price is €200
includes taxes & fees
5 Apr - 6 Apr
Plaza San Antonio Hotel & Spa, Autograph Collection

Extended Stay America Premier Suites - San Antonio - Schertz

Extended Stay America Premier Suites - San Antonio - Schertz
2.5 star property
29.4 km from Medical Center District
9.2 out of 10, Wonderful, (219 reviews)
"Room was excellent and staff were friendly and helpful. Will stay here again"
United States
Sharon
The price is €84
includes taxes & fees
16 Mar - 17 Mar
Extended Stay America Premier Suites - San Antonio - Schertz

Best Western Garden Inn

Best Western Garden Inn
2.5 star property
Uptown, 21.2 km from Medical Center District
8.2 out of 10, Very good, (1,002 reviews)
"Clean room, very friendly staff, grounds were well kept and breakfast was great!"
United States
Gregory
The price is €65
includes taxes & fees
22 Mar - 23 Mar
Best Western Garden Inn

Spark by Hilton San Antonio Dominion

Spark by Hilton San Antonio Dominion
3.0 star property
19.5 km from Medical Center District
8.8 out of 10, Excellent, (311 reviews)
"Clean room, comfy bed, nice staff."
United States
Kaitlyn
The price is €64
includes taxes & fees
13 Apr - 14 Apr
Spark by Hilton San Antonio Dominion

stayAPT Suites San Antonio-Randolph

stayAPT Suites San Antonio-Randolph
2.5 star property
Live Oak, 24.4 km from Medical Center District
8.8 out of 10, Excellent, (499 reviews)
"Well maintained property, quiet, very comfortable, easy access, with resturants and services close."
United States
David
stayAPT Suites San Antonio-Randolph

Staybridge Suites San Antonio Lackland AFB Area by IHG

Staybridge Suites San Antonio Lackland AFB Area by IHG
3.0 star property
Far West Side, 9.6 km from Medical Center District
9.6 out of 10, Exceptional, (426 reviews)
"Breakfast, evening social, kitchenettes, friendly staff, good location to visit downtown and Lackland Airforce base."
United States
Kelly
The price is €93
includes taxes & fees
6 Apr - 7 Apr
Staybridge Suites San Antonio Lackland AFB Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Medical Center District

Find the best Medical Center District areas for the activities you enjoy most. Learn more about Medical Center District
Learn more about Medical Center District

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown

If you're spending some time in Uptown, San Antonio Zoo and Aquarium and Marion Koogler McNay Art Museum are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

Arena District

If you're spending some time in Arena District, Frost Bank Center and Freeman Coliseum are top sights worth seeing.

Top Medical Center District Hotel Reviews

Frequently asked questions

What is Medical Center District like?
Travellers are sure to enjoy a stay in San Antonio's Medical Center District neighbourhood. Are you looking for Medical Center District travel tips? Make sure that you visit USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're in the neighbourhood.
What's a favourite hotel to stay in Medical Center District?
Based on Expedia customer reviews, Drury Inn & Suites San Antonio Northwest Medical Center is the highest ranked property in Medical Center District. This hotel offers free breakfast and an indoor pool. Other favourite options in the area include Fairfield Inn & Suites by Marriott San Antonio Medical Center and Courtyard by Marriott Medical Center San Antonio.
How many hotels will I be able to find in Medical Center District?
Expedia has 121 hotels and other accommodation options in Medical Center District to choose from, making this an ideal home base for exploring the greater San Antonio area.
If I need to cancel my hotel reservation in Medical Center District, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to review the top deals on offer in Medical Center District.
What can I see and do in this San Antonio neighbourhood?
USAA Corporate Office Headquarters, Cinemark San Antonio 16 and The San Antonio Art Institute are just a few attractions to check out in Medical Center District. Wonderland of the Americas Mall and Regal Huebner Oaks are also worth a visit when you're out sightseeing in San Antonio.

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