San Luis Obispo Hotel Guide - Hotels with Spa in San Luis Obispo, California

Start date: Check-in selected.
End date: Check-out
    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on San Luis Obispo Hotels with Spa

Top San Luis Obispo Hotels with Spa

Our top choices for San Luis Obispo hotels with a spa

Quality Suites Downtown San Luis Obispo
Free daily buffet breakfast

Quality Suites Downtown San Luis Obispo

3.0 star property
9.4 out of 10, Exceptional, (1213)
"Great stay"
The price is €139
includes taxes & fees
19 Oct - 20 Oct
Quality Suites Downtown San Luis Obispo
Hotel San Luis Obispo
Rooftop terrace

Hotel San Luis Obispo

4.5 star property
9.6 out of 10, Exceptional, (526)
"Great location. "
The price is €328
includes taxes & fees
1 Oct - 2 Oct
Hotel San Luis Obispo
University Inn
Free daily on-the-go breakfast

University Inn

2.0 star property
8.0 out of 10, Very good, (1008)
"Convenient location. "
University Inn
Madonna Inn
Caveman | Bathroom

Madonna Inn

3.5 star property
9.2 out of 10, Wonderful, (1246)
"the pool was awesome, the restaurants were great, friendly, helpful staff "
The price is €171
includes taxes & fees
29 Sept - 30 Sept
Madonna Inn
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
Outdoor pool, open 10:00 AM to 10:00 PM, pool loungers

La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown

3.0 star property
9.0 out of 10, Wonderful, (1692)
"Wonderful place to stay "
The price is €143
includes taxes & fees
23 Sept - 24 Sept
La Quinta Inn & Suites by Wyndham San Luis Obispo Downtown
Vagabond Inn San Luis Obispo
Outdoor pool, open 9:00 AM to 9:00 PM, pool loungers

Vagabond Inn San Luis Obispo

2.0 star property
8.4 out of 10, Very good, (1175)
"Always a great visit"
The price is €74
includes taxes & fees
29 Sept - 30 Sept
Vagabond Inn San Luis Obispo
Mission Inn San Luis Obispo
Standard Room, 2 Double Beds, Non Smoking, Mountain View

Mission Inn San Luis Obispo

2.0 star property
7.8 out of 10, Good, (864)
"Great customer service at check in. "
The price is €100
includes taxes & fees
20 Sept - 21 Sept
Mission Inn San Luis Obispo
HOTEL CERRO, Autograph Collection
Reception

HOTEL CERRO, Autograph Collection

4.0 star property
9.2 out of 10, Wonderful, (459)
"We had a great stay"
The price is €222
includes taxes & fees
1 Oct - 2 Oct
HOTEL CERRO, Autograph Collection
Motel 6 San Luis Obispo, CA - South
Desk, free WiFi, bed sheets

Motel 6 San Luis Obispo, CA - South

2.0 star property
8.4 out of 10, Very good, (1014)
"nice staff and I had a good experience for my stay with my dogs."
The price is €73
includes taxes & fees
1 Oct - 2 Oct
Motel 6 San Luis Obispo, CA - South
Best Western Plus Royal Oak Hotel
Outdoor pool, a heated pool, pool umbrellas, pool loungers

Best Western Plus Royal Oak Hotel

2.5 star property
8.6 out of 10, Excellent, (1006)
"Great breakfast options!"
The price is €129
includes taxes & fees
7 Oct - 8 Oct
Best Western Plus Royal Oak Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top San Luis Obispo Hotel Reviews

La Cuesta Inn, BW Signature Collection

La Cuesta Inn, BW Signature Collection

10/10 Excellent
"Rooms clean, staff kind but building definitely very old."
Crystal 1-night trip
Posted 1 day ago
La Cuesta Inn, BW Signature Collection

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Looking for a spa hotel in San Luis Obispo?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travellers love the wineries and restaurants in San Luis Obispo. Enjoy the art galleries and beaches during your holiday. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in San Luis Obispo?
Madonna Inn is a top spa hotel featuring a fitness centre, tennis courts, a bar and an outdoor pool. Treat yourself to a facial, body scrub or Swedish massage at the on-site spa. Other popular spa hotels in San Luis Obispo include Hotel San Luis Obispo and HOTEL CERRO, Autograph Collection.
How many spa hotels will I find in San Luis Obispo?
Among Expedia's 201 accommodation options in San Luis Obispo, there are 3 spa hotels.
What's there to see and do in San Luis Obispo?
Enjoy all that San Luis Obispo has to offer and visit Fremont Theater, Downtown SLO Farmers' Market and Mission San Luis Obispo de Tolosa. If you have extra time while you're in the area, you might want to see Cerro San Luis Obispo and Performing Arts Center.
What is a San Luis Obispo spa hotel?
Spa hotels in San Luis Obispo provide lodging and have a full on-site spa which offers services including massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.