San Luis Obispo Hotel Guide - Hotels with Spa in San Luis Obispo, California

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Check availability on San Luis Obispo Hotels with Spa

Our top choices for San Luis Obispo hotels with a spa

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Oxford Suites Paso Robles

Oxford Suites Paso Robles

Oxford Suites Paso Robles
3.5 star property
Paso Robles
9.6 out of 10, Exceptional, (1645)
"Super clean, great location, amazing staff. Would absolutely stay here again"
United States
Thomas
The price is €224
includes taxes & fees
31 Dec - 1 Jan 2026
Oxford Suites Paso Robles
Restaurant
The Agrarian Hotel, BW Signature Collection

The Agrarian Hotel, BW Signature Collection

The Agrarian Hotel, BW Signature Collection
2.5 star property
Arroyo Grande
9.6 out of 10, Exceptional, (1005)
"This is a wonderful place to stay. Beautiful interior, cozy common area, nice people, ideal location. "
United States
Michael
The price is €130
includes taxes & fees
21 Dec - 22 Dec
The Agrarian Hotel, BW Signature Collection
Yoga
Allegretto Vineyard Resort Paso Robles

Allegretto Vineyard Resort Paso Robles

Allegretto Vineyard Resort Paso Robles
4.5 star property
River Oaks
9.6 out of 10, Exceptional, (1468)
"Beautiful place, well located"
Australia
Mario
The price is €243
includes taxes & fees
21 Dec - 22 Dec
Allegretto Vineyard Resort Paso Robles
Morro Suite | Living area
Hotel San Luis Obispo

Hotel San Luis Obispo

Hotel San Luis Obispo
4.5 star property
Downtown San Luis Obispo
9.4 out of 10, Exceptional, (549)
"Great space, friendly staff and good restaurants - we thoroughly enjoyed ourselves. "
United States
michelle
The price is €337
includes taxes & fees
1 Jan - 2 Jan 2026
Hotel San Luis Obispo
Exterior
Cayucos Sunset Inn B&B

Cayucos Sunset Inn B&B

Cayucos Sunset Inn B&B
3.5 star property
Cayucos
9.8 out of 10, Exceptional, (195)
"Great place to stay"
United States
Jason
The price is €167
includes taxes & fees
22 Dec - 23 Dec
Cayucos Sunset Inn B&B
Reception
HOTEL CERRO, Autograph Collection

HOTEL CERRO, Autograph Collection

HOTEL CERRO, Autograph Collection
4.0 star property
Downtown San Luis Obispo
9.2 out of 10, Wonderful, (468)
"We had a great stay"
United States
ADALBERT
The price is €207
includes taxes & fees
23 Dec - 24 Dec
HOTEL CERRO, Autograph Collection
Property entrance
Avila Village Inn

Avila Village Inn

Avila Village Inn
3.5 star property
Avila Beach
9.2 out of 10, Wonderful, (1000)
"We really enjoyed our stay-room was clean-lobby was cozy and the entire place has tons of character!! "
United States
Alfredo
Avila Village Inn
Property grounds
Avila La Fonda Hotel

Avila La Fonda Hotel

Avila La Fonda Hotel
4.0 star property
Avila Beach
9.6 out of 10, Exceptional, (1000)
"Very nice hotel. Great for and rest and relaxation kind of vacation"
United States
Princess
The price is €197
includes taxes & fees
21 Dec - 22 Dec
Avila La Fonda Hotel
Caveman | Bathroom
Madonna Inn

Madonna Inn

Madonna Inn
3.5 star property
San Luis Obispo
9.2 out of 10, Wonderful, (1327)
"Great place."
United States
Caeli
The price is €173
includes taxes & fees
4 Jan - 5 Jan 2026
Madonna Inn
Outdoor pool
Sea Pines Resort

Sea Pines Resort

Sea Pines Resort
3.0 star property
Los Osos
8.2 out of 10, Very good, (411)
"Nice staff."
United States
Ann
Sea Pines Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Spa hotels with pools in San Luis Obispo

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Oxford Suites Paso Robles

Oxford Suites Paso Robles

Oxford Suites Paso Robles
3.5 star property
Paso Robles
9.6 out of 10, Exceptional, (1645)
The price is €224
includes taxes & fees
31 Dec - 1 Jan 2026
Oxford Suites Paso Robles
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Spa hotels with hot tubs in San Luis Obispo

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Oxford Suites Paso Robles

Oxford Suites Paso Robles

Oxford Suites Paso Robles
3.5 star property
Paso Robles
9.6 out of 10, Exceptional, (1645)
The price is €224
includes taxes & fees
31 Dec - 1 Jan 2026
Oxford Suites Paso Robles
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Spa hotels with free breakfast in San Luis Obispo

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Oxford Suites Paso Robles

Oxford Suites Paso Robles

Oxford Suites Paso Robles
3.5 star property
Paso Robles
9.6 out of 10, Exceptional, (1645)
The price is €224
includes taxes & fees
31 Dec - 1 Jan 2026
Oxford Suites Paso Robles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top San Luis Obispo Hotel Reviews

Madonna Inn

Madonna Inn

10/10 Excellent
"Lovely stay at the Iconic Madonna Inn. Bar was excellent as was restaurant. Xmas decorations were wonderful."
Richard 1-night trip
Posted 1 day ago
Madonna Inn

Frequently asked questions

Looking for a spa hotel in San Luis Obispo?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travellers love the wineries and restaurants in San Luis Obispo. Enjoy the art galleries and beaches during your holiday. Hotels with spas are a great way to break out of your daily routine and add a layer of luxury to your stay.
What is the best spa hotel in San Luis Obispo?
Madonna Inn is a top spa hotel featuring a fitness centre, tennis courts, a bar and an outdoor pool. Treat yourself to a facial, body scrub or Swedish massage at the on-site spa. Other popular spa hotels in San Luis Obispo include Hotel San Luis Obispo and HOTEL CERRO, Autograph Collection.
How many spa hotels will I find in San Luis Obispo?
Among Expedia's 203 accommodation options in San Luis Obispo, there are 3 spa hotels.
What's there to see and do in San Luis Obispo?
Enjoy all that San Luis Obispo has to offer and visit Fremont Theater, Downtown SLO Farmers' Market and San Luis Obispo Superior Court. If you have extra time while you're in the area, you might want to see Mission San Luis Obispo de Tolosa and Ah Louis Store.
What is a San Luis Obispo spa hotel?
Spa hotels in San Luis Obispo provide lodging and have a full on-site spa which offers services including massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.