Guayaquil Hotel Guide - Santa Ana Port hotels in Guayaquil, Ecuador.

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Tonight
26 Dec - 27 Dec
Tomorrow
27 Dec - 28 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Santa Ana Port hotels

Exterior
Luxva Hotel Boutique

Luxva Hotel Boutique

Luxva Hotel Boutique
3.0 star property
Urdesa, 1.6 km from Santa Ana Port
9.4 out of 10, Exceptional, (173)
"Breakfast was ok and the staff is wonderful!"
United States
James
The price is €71
27 Dec - 28 Dec
Luxva Hotel Boutique
Outdoor pool, pool loungers
Radisson Hotel Guayaquil

Radisson Hotel Guayaquil

Radisson Hotel Guayaquil
5.0 star property
Kennedy, 2 km from Santa Ana Port
9.2 out of 10, Wonderful, (636)
"Good service "
United States
Genny
The price is €69
4 Jan - 5 Jan 2026
Radisson Hotel Guayaquil
Rooftop bar, al fresco dining, open daily
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

Wyndham Garden Guayaquil
3.5 star property
Simón Bolívar, 3.1 km from Santa Ana Port
9.0 out of 10, Wonderful, (1001)
"Room was "
United States
Aditi
The price is €71
9 Jan - 10 Jan 2026
Wyndham Garden Guayaquil
Lobby
Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil

Courtyard by Marriott Guayaquil
3.5 star property
Kennedy, 2.4 km from Santa Ana Port
8.8 out of 10, Excellent, (1001)
"Great stay and they were able to accommodate our last minute booking. We had an amazing view of the city and the room was spotless."
United States
Cesar
The price is €68
4 Jan - 5 Jan 2026
Courtyard by Marriott Guayaquil
Lobby
Hilton Colon Guayaquil

Hilton Colon Guayaquil

Hilton Colon Guayaquil
4.5 star property
Kennedy, 2.4 km from Santa Ana Port
8.6 out of 10, Excellent, (821)
"Great room"
United States
Trevor
The price is €90
10 Jan - 11 Jan 2026
Hilton Colon Guayaquil
Outdoor pool, open 8:00 AM to 10:00 PM, pool loungers
Cedros Inn Boutique Hotel

Cedros Inn Boutique Hotel

Cedros Inn Boutique Hotel
3.5 star property
Urdesa, 1.6 km from Santa Ana Port
8.4 out of 10, Very good, (84)
"The staff went above and beyond to accommodate any special needs that we had. The place itself is clean and very beautiful. Great location, near many restaurants (and Chabad). 10/10 recommend booking your stay here. "
United States
Chana
The price is €59
26 Jan - 27 Jan 2026
Cedros Inn Boutique Hotel
Terrace/patio
Hotel Marcelius

Hotel Marcelius

Hotel Marcelius
3.5 star property
Kennedy, 2.2 km from Santa Ana Port
8.2 out of 10, Very good, (224)
"Excellent price easy to book"
United States
Carlos
Hotel Marcelius
Lobby sitting area
MC Suites

MC Suites

MC Suites
3.5 star property
Kennedy, 2.2 km from Santa Ana Port
8.2 out of 10, Very good, (133)
"Great place!!!!!!"
Mexico
Inti
MC Suites
Interior
Hostal Macaw

Hostal Macaw

Hostal Macaw
3.0 star property
Kennedy, 2.9 km from Santa Ana Port
10.0 out of 10, Exceptional, (9)
"Wonderful hosts and felt like home "
United States
Tina
The price is €60
9 Jan - 10 Jan 2026
Hostal Macaw
Deluxe Loft | Living area
PRAGA APARTMENTS

PRAGA APARTMENTS

PRAGA APARTMENTS
4.0 star property
Urdesa, 1.4 km from Santa Ana Port
9.0 out of 10, Wonderful, (15)
"Great place to stay at "
United States
Eric
PRAGA APARTMENTS
Living area
Pachamac House

Pachamac House

Pachamac House
2.0 star property
3 km from Santa Ana Port
The price is €17
27 Dec - 28 Dec
Pachamac House
Reception
Hotel Sada

Hotel Sada

Hotel Sada
3.0 star property
Roca, 4.2 km from Santa Ana Port
9.8 out of 10, Exceptional, (8)
"El personal muy atento. "
United States
José
The price is €39
27 Dec - 28 Dec
Hotel Sada
Children’s activities
Oro Verde Guayaquil

Oro Verde Guayaquil

Oro Verde Guayaquil
5.0 star property
Downtown Guayaquil, 3.9 km from Santa Ana Port
9.4 out of 10, Exceptional, (1002)
"Great room, excellent breakfast options! "
United States
Francisco
The price is €81
27 Dec - 28 Dec
Oro Verde Guayaquil
Executive Suite, Kitchenette, City View | Private kitchen
Suitesecu Rentals Guayaquil

Suitesecu Rentals Guayaquil

Suitesecu Rentals Guayaquil
4.5 star property
Simón Bolívar, 3.6 km from Santa Ana Port
9.4 out of 10, Exceptional, (8)
"You can walk to the airport."
United States
Digna
The price is €28
4 Jan - 5 Jan 2026
Suitesecu Rentals Guayaquil
Terrace/patio
Hotel del Parque

Hotel del Parque

Hotel del Parque
4.5 star property
6 km from Santa Ana Port
9.8 out of 10, Exceptional, (108)
"Friendly staff. We arrived very early and they were ablemto accommodate an early check-in. The hotel is beautiful "
Canada
Victor
The price is €420
1 Jan - 2 Jan 2026
Hotel del Parque
Double Room
Casa Serena

Casa Serena

Casa Serena
2.5 star property
Simón Bolívar, 3.4 km from Santa Ana Port
9.2 out of 10, Wonderful, (54)
"the property was ok for the price"
United States
ASONG
Casa Serena
Outdoor pool
Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG

Holiday Inn Guayaquil Airport by IHG
3.5 star property
4.6 km from Santa Ana Port
9.4 out of 10, Exceptional, (1001)
"Great stay"
United States
Susan
The price is €68
29 Dec - 30 Dec
Holiday Inn Guayaquil Airport by IHG
43-inch flat-screen TV with digital channels, TV, Netflix
Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE

Luxury Suites Riverfront GYE
3.5 star property
Puerto Santa Ana, 4.9 km from Santa Ana Port
9.4 out of 10, Exceptional, (100)
"The apartment was in a great location and very clean and well maintained."
United States
Rolando
The price is €92
5 Jan - 6 Jan 2026
Luxury Suites Riverfront GYE
Restaurant
Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil

Ibis Styles El Malecon Guayaquil
4.0 star property
Downtown Guayaquil, 5.2 km from Santa Ana Port
9.4 out of 10, Exceptional, (274)
"Great location and great hotel "
United States
José
The price is €57
9 Jan - 10 Jan 2026
Ibis Styles El Malecon Guayaquil
2 restaurants, breakfast, lunch, dinner served; Regional cuisine
Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel

Sheraton Guayaquil Hotel
5.0 star property
Simón Bolívar, 3.2 km from Santa Ana Port
9.0 out of 10, Wonderful, (606)
"Very friendly front desk thank you for a comfortable and enjoyable stay. "
United States
Andrew
The price is €79
4 Jan - 5 Jan 2026
Sheraton Guayaquil Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Ana Port Hotel Reviews

Oro Verde Guayaquil

Oro Verde Guayaquil

10/10 Excellent
"Clean room great staff and delicious food . Would definitely recommend this place. See you in 6 months. Thanks 🙏"
Glubis 3-night trip
Posted 1 day ago
Oro Verde Guayaquil

Hotels near other Santa Ana Port attractions

Churute Mangroves Ecological Reserve

Explore the great outdoors at Churute Mangroves Ecological Reserve, a lovely green space in Guayaquil. While you're in the area, find time to visit its shops.
See properties

Alban Borja Commercial Center

During your trip to Guayaquil, you can search for that perfect souvenir at Alban Borja Commercial Center. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Santa Ana Port?
Santa Ana Port is located in an area of Guayaquil known for its major shopping area. If you're looking for a convenient place to stay, take a look at the 30 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near Santa Ana Port?
Adjacent to Santa Ana Port, Apartterrazas Guayaquil is one of the top choices for your stay based on our traveller data, and this hotel offers free parking and in-room kitchenettes. Other good options within a short distance include Iguanazu Bed & Breakfast and NOVAPARK ILANES.
How many hotels will I find near Santa Ana Port?
Expedia has 30 hotels and other accommodation options within a mile from Santa Ana Port.
If I need to cancel the hotel reservation for my stay near Santa Ana Port, will I receive a refund?
Yes, the majority of hotel room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to review the best deals available near Santa Ana Port.
What can I see and do near Santa Ana Port?
Study the collections at Museum of Anthropology and Contemporary Art, Nahim Isaias Museum or Municipal Museum of Guayaquil. George Capwell Stadium, Clock Tower and Crystal Palace are some of the local landmarks to explore. You can enjoy live performances at Teatro Sanchez Aguilar and Supercines Orellana.