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Santa Cruz Hotels

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Our top choices for Santa Cruz hotels

Hotel Vendimia Parador

Hotel Vendimia Parador
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (79)
"Great place for a weekend of wines and relax. My gf and I really enjoyed the facilities, good breakfast, owners provide great customer service. "
United States
Stephen
The price is €84
18 Jan - 19 Jan 2026
Hotel Vendimia Parador

La Perla Hotel

La Perla Hotel
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (101)
"Nice stay"
United States
George
La Perla Hotel

Santa Cruz Plaza

Santa Cruz Plaza
4.0 star property
Santa Cruz
8.6 out of 10, Excellent, (335)
"Yes all great."
United States
Barrett
The price is €108
25 Dec - 26 Dec
Santa Cruz Plaza

Hotel Cava Colchagua

Hotel Cava Colchagua
4.0 star property
Santa Cruz
8.8 out of 10, Excellent, (170)
"Interesting and beautiful place to stay. Barrel rooms are comfortable. Staff are very pleasant and accomodating. Food at the restaurant was fantastic. Shower was not the best."
Canada
Anonymous traveller
Hotel Cava Colchagua

TerraViña

TerraViña
3.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (203)
"It is situated in the midfle of a vineyard - so it is certainly quiet. Great base for exploring (by own car or taxi) the Uco Valley. It is a 20 minute walk to the road! Simple but stylish place. Gym is just for show… $300 dollars would sort it out! Staff were very helpful. This is a unique place for a wine aficionado! "
United Kingdom
Paul
The price is €138
24 Dec - 25 Dec
TerraViña

Hotel Boutique Solaz Bella Vista de Colchagua

Hotel Boutique Solaz Bella Vista de Colchagua
3.0 star property
Santa Cruz
9.4 out of 10, Exceptional, (96)
"Wonderful place, great people, access to wine tastings."
United States
Irving
The price is €78
22 Jan - 23 Jan 2026
Hotel Boutique Solaz Bella Vista de Colchagua

Barrica Lodge

Barrica Lodge
4.0 star property
Santa Cruz
8.0 out of 10, Very good, (1)
The price is €117
16 Jan - 17 Jan 2026
Barrica Lodge

Hotel Boutique Grand Cru

Hotel Boutique Grand Cru
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (8)
"Excellent staff, beautiful rooms and amenities "
United States
Jonathan
The price is €99
24 Dec - 25 Dec
Hotel Boutique Grand Cru

Casa Calfu

Casa Calfu
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (63)
"Charming place ! "
France
Ruxandra
Casa Calfu

Hotel Boutique Vendimia Premium

Hotel Boutique Vendimia Premium
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (136)
"Loved the rustic hotel and Mauricio and Carla are awesome hosts! Great location and an amazing place to stay. Highly recommended. "
United States
Orlando
The price is €103
26 Dec - 27 Dec
Hotel Boutique Vendimia Premium

Colchagua Tiny Lodge

Colchagua Tiny Lodge
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (4)
"The Tiny Lodge has so many amenities thoughtfully packed into a cozy package. Loved the thought put into surfaces and spaces to sit your personal belongings. The bed is luxurious. 10 out of 10. "
United States
Trisha
The price is €173
24 Dec - 25 Dec
Colchagua Tiny Lodge

Vik Chile

Vik Chile
5.0 star property
San Vicente
9.2 out of 10, Wonderful, (156)
"If I could rate this place 11/10 I would. Despite the fact the hotel and surrounding grounds are incredible, the staff and experiences are what make this place. We have never been somewhere with such exceptional service. Would highly recommend the trip out of Santiago to anyone visiting Chile"
United Kingdom
Amy
The price is €594
7 Jan - 8 Jan 2026
Vik Chile

Noi Blend Colchagua

Noi Blend Colchagua
3.0 star property
Palmilla
9.0 out of 10, Wonderful, (137)
"Great place, attentive staff, made our stay very enjoyable. "
United States
Raymond
The price is €127
25 Dec - 26 Dec
Noi Blend Colchagua

Hotel Ontiveros

Hotel Ontiveros
3.5 star property
San Fernando
9.6 out of 10, Exceptional, (21)
"Amplia y comoda habitacion. Personal de recepcion muy amable y colaborador "
Mexico
Eileen
Hotel Ontiveros

Hacienda Histórica Marchigüe

Hacienda Histórica Marchigüe
3.5 star property
Marchihue
8.0 out of 10, Very good, (13)
"An unusual place to stay. the staff were great and very helpful. Enjoyed the quiet and food"
United States
Anonymous traveller
Hacienda Histórica Marchigüe

Hotel Boutique Raices

Hotel Boutique Raices
3.5 star property
Curicó
9.4 out of 10, Exceptional, (40)
"I enjoyed my stay here. "
Canada
Nick
Hotel Boutique Raices

Hotel Viña La Playa

Hotel Viña La Playa
3.5 star property
Peralillo
8.2 out of 10, Very good, (17)
"Nice place, if you want to rest this is the place"
Mexico
Manuel
Hotel Viña La Playa
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Stay near popular Santa Cruz attractions

Learn more about Santa Cruz

Nestled in the heart of wine country, Santa Cruz invites visitors to taste world-class Colchagua Valley wines at family-owned vineyards. Museum of Colchagua showcases impressive pre-Columbian artefacts while the Plaza de Armas offers local crafts and regional foods on weekends.

Rows of vineyards, Santa Cruz, Chile

Top Santa Cruz Hotel Reviews

More cheap stays in Santa Cruz

Frequently asked questions

What's the best place for a stay in Santa Cruz?
Hotel Vendimia Parador is a favourite property for Expedia customers. This hotel offers an outdoor pool and an indoor pool. Reviews from our site also recommend Casa Calfu and La Perla Hotel as top options for your visit. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
Hosteria No me Olvides: This holiday home rental outside Santa Cruz offers a terrace and cable TV to help you feel comfortable in your new surroundings. Another good choice for your trip to Santa Cruz is The ambush. Field and comfort. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! The majority of hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What's the best place to stay on a budget in Santa Cruz?
Based on our traveller reviews, Hostal Gomero is a top choice for a less expensive stay. Other options to stay on the cheap include Casa Suiza - Hostel and Hostal Cepa Noble. View all budget hotels in Santa Cruz.
What's the best family accommodation in Santa Cruz?
Santa Cruz Plaza is a hotel with an outdoor pool and a free children's club, and it's a top choice on Expedia for families. Also, children of all ages will enjoy a visit to Colchagua Campo y Vino. Find more child-friendly accommodations in Santa Cruz.
What's the best dog-friendly accommodation option in Santa Cruz?
Hotel Vendimia Parador is a top hotel for people travelling with their pets, and offers an indoor pool and an outdoor pool for its human guests. Two other good options for you and your pet include Hotel Hoja de Parra and Parcela con tranque, sala de juegos, terraza,. See more pet-friendly hotel accommodations in Santa Cruz.
What's the best luxury hotel in Santa Cruz?
Vibo Wine Lodge is a luxury lodge with a winery and private balconies, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Find more luxury hotels in Santa Cruz.
What are some accommodation options with pools in Santa Cruz?
Hotel Vendimia Parador is a top hotel with an indoor pool, an outdoor pool and free WiFi. View all hotels with pools in Santa Cruz.
What is the best spa hotel in Santa Cruz?
Santa Cruz Plaza is a top spa hotel featuring a rooftop terrace, a 24-hour fitness centre, a free children's club and a bar. Treat yourself to a facial, body scrub or hydrotherapy at the on-site spa. Other popular spa hotels in Santa Cruz include Hotel Cava Colchagua and Hotel Boutique Solaz Bella Vista de Colchagua. See all spa hotels in Santa Cruz.
What's it like to stay in Santa Cruz?
Visitors to Santa Cruz will definitely enjoy the wineries, local tours and restaurants. Tourists can also enjoy so much more including its casinos. In Santa Cruz, there are 34 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What is there to see in Santa Cruz?
Wine tasting is a great activity, and Lapostolle Clos Apalta Winery is one place to visit. A couple of additional sights to add to your itinerary are Casino Colchagua and Millahue Valley. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
What's the seasonal weather in Santa Cruz?
The hottest months are usually January and February, with an average temperature of 21°C, while the coldest months are July and August, with an average of 10°C. Average annual precipitation for Santa Cruz is 743 mm.