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Santa Fe Hotels

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Check prices for these dates

Tonight
25 Dec - 26 Dec
Tomorrow
26 Dec - 27 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Santa Fe hotels

Restaurant
Hotel Anachoreo

Hotel Anachoreo

Hotel Anachoreo
3.0 star property
Santa Fe
9.4 out of 10, Exceptional, (36)
Experience this charming B&B with complimentary breakfast, WiFi, and parking. Unwind with massages after exploring the nearby Town Square and Mercado, or relax at the garden terrace and lounge.
"Wonderful place at a beautiful stay . I can recommend it totally ! "
United States
Ingmar
Hotel Anachoreo
Terrace/patio
La Qhia Eco Retreat

La Qhia Eco Retreat

La Qhia Eco Retreat
2.5 star property
Santa Fe
8.0 out of 10, Very good, (18)
Escape to this eco-friendly hostal near Town Square and Mercado. Unwind with Thai massages at the on-site spa, savour meals at Cayucos Restaurante & Bar, or relax on the terrace. The property includes a snack bar and free parking for convenient exploration.
"Very noisy due to neighbouring roosters & dogs at night. Food good & easy access. "
Canada
Heather
La Qhia Eco Retreat
Outdoor pool
HOTEL VISTA LAGO

HOTEL VISTA LAGO

HOTEL VISTA LAGO
3.0 star property
La Pena
9.2 out of 10, Wonderful, (81)
Splash into the inviting outdoor pool or savour cuisine at the restaurant while enjoying complimentary breakfast, WiFi, and parking. With 2 bars/lounges and proximity to Parque Acuatico Italia Guadalupe Panama, relaxation comes naturally here.
"perfect for an overnight stop on the road, beautiful view of the lake and good restaurant"
Canada
Géraldine
The price is €71
includes taxes & fees
22 Jan - 23 Jan 2026
HOTEL VISTA LAGO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Fe attractions

Alto de Piedra Waterfall

3.3/5 (3 reviews)
Commune with nature and explore the great outdoors at Alto de Piedra Waterfall during your travels in Santa Fe. While you're in the area, wander around the natural setting.
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Town Square

3.6/5 (7 reviews)
You can find out about the history of Santa Fe when you stop by Town Square. Amble around the area's riverfront or visit its churches.
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Learn more about Santa Fe

Escape to Santa Fe! Enjoy its adventures and natural setting.

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After the rain...
Photo by Binin Urlaub
Open Photo by Binin Urlaub

Top Santa Fe Hotel Reviews

HOTEL VISTA LAGO

HOTEL VISTA LAGO

10/10 Excellent
"Wow! I can’t say enough about this place, it’s a hidden gem in Boquete. The view is spectacular, beautiful private room, very comfortable bed, spotless everything. Daniel and Andrea are very friendly and proud of their property, they have thought of every detail.Thank you for making us the most amazing breakfast on the terrace, can’t wait to come back, congratulations!!"
Richard 1-night trip
Posted 3 weeks ago
HOTEL VISTA LAGO

More cheap stays in Santa Fe

Cabana Vergara Santa Fe

Cabana Vergara Santa Fe

Provincia de Veraguas, Panama Panama
The price is €140 per night from 20 Jan to 21 Jan
€140
20 Jan - 21 Jan 2026
includes taxes & fees

Frequently asked questions

Where is the best place to stay in Santa Fe?
Based on our traveller data, Hotel Anachoreo is one of the top choices for your stay. This B&B offers free breakfast and a restaurant. Other good choices for your stay include La Qhia Eco Retreat and Rainforest Yasmin Hotel. See all available top hotels, or vacation rentals in Santa Fe.
What are some of the best holiday rentals that Santa Fe has to offer?
Cabana Vergara Santa Fe: This highly rated holiday home rental in Santa Fe offers a patio, a garden and air conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and kitchenware. See all vacation rentals in Santa Fe.
If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?
Yes, most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a non-refundable reservation, it may still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.
What is staying in Santa Fe like?
Visitors will definitely enjoy all that Santa Fe has to offer. In Santa Fe, there are 4 hotels and other accommodation options to choose from. Find out more about Santa Fe.
What is there to see in Santa Fe?
Landmarks like Town Square and Mercado might be worth a visit. Natural beauty is on display at Alto de Piedra Waterfall, Sante Fe National Park and Quebrada Las Trancas Spa. Additionally, you might want to add Orchid House to your itinerary. Take a look at what more there is to see and do in Expedia's Santa Fe guide.
What's the seasonal weather in Santa Fe?
The hottest months are usually March and April, with an average temperature of 27°C, while the coldest months are January and December, with an average of 25°C. The rainiest months in Santa Fe are October, August, June and November, with each month seeing an average of 447 mm of rainfall.