Photo by Norberto Moctezuma Gomez

Holiday Rentals in Santana

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Our top choices for Santana holiday rentals

Nature's Lodge Escape

Nature's Lodge Escape
Sabana Grande
The price is €72
includes taxes & fees
26 Jan - 27 Jan 2026
Nature's Lodge Escape

Buye Apartments

Buye Apartments
3.0 star property
Cabo Rojo
8.0 out of 10, Very good, (24)
"It was outstanding "
United States
Jorge
The price is €162
includes taxes & fees
1 Jan - 2 Jan 2026
Buye Apartments

Finca Don Chaguin - Exquisite sunset views in the beautiful mountains of Utuado

Finca Don Chaguin - Exquisite sunset views in the beautiful mountains of Utuado
Utuado
10.0 out of 10, Exceptional, (2)
"So happy we were the first ones to stay at this new cabin rental. The area is beautiful and the sunsets were gorgeous. we couldn’t have been happier with our stay. The cabin is so cozy with a very spacious outdoor fully equipped kitchen. The bed was super comfy and the AC was very cold. We loved watching the sheep grazing on the property. The owners even offer private tours of various places. My only regret is not planning to spend more time here during our Puerto Rico trip. Utuado itself is...
United States
Jose S.
The price is €206
includes taxes & fees
9 Jan - 10 Jan 2026
Finca Don Chaguin - Exquisite sunset views in the beautiful mountains of Utuado

Palmeras Beach Apartments

Palmeras Beach Apartments
3.0 star property
Guanica
10.0 out of 10, Exceptional, (11)
"The way was everything organized "
United States
Jesus
The price is €152
includes taxes & fees
28 Jan - 29 Jan 2026
Palmeras Beach Apartments

The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico
Adjuntas
9.6 out of 10, Exceptional, (13)
"A beautiful home and a great host! Strongly recommend! "
United States
Brandon C.
The price is €254
includes taxes & fees
7 Jan - 8 Jan 2026
The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

Blue House Joyuda

Blue House Joyuda
3.5 star property
Cabo Rojo
9.4 out of 10, Exceptional, (32)
"Raul and his staff Laura were excellent. They make us feel like home. The pool was neat and clean, refreshing. Highly recommend and the beach and market are pretty close. "
United States
Edwin
The price is €134
includes taxes & fees
11 Jan - 12 Jan 2026
Blue House Joyuda

Villa Flamingo Cabo Rojo | Buye Beach | Pool |

Villa Flamingo Cabo Rojo | Buye Beach | Pool |
Cabo Rojo
9.8 out of 10, Exceptional, (10)
"Absolutely loved the spot."
United States
Erin D.
Villa Flamingo Cabo Rojo | Buye Beach | Pool |

A few steps away from paradise

A few steps away from paradise
Guanica
9.2 out of 10, Wonderful, (23)
"Everything was just like in the photo from the website, interior in a nautical style, silence, tranquility, Caribbean comfort, a full kitchen that allows you to cook something delicious, beaches within walking distance, thank you... Also grateful for the help in solving questions, the answers were instant, thank you..."
United States
Oleg
The price is €121
includes taxes & fees
2 Jan - 3 Jan 2026
A few steps away from paradise

High Tide Guesthouse PR

High Tide Guesthouse PR
Lajas
9.4 out of 10, Exceptional, (24)
"Very convenient for viewing the bioluminescence at La Paguera (which was excellant). Jessica was very quick to respond and helpful with her communications. Place was charming. Easy parking on the street."
United States
Paula
The price is €125
includes taxes & fees
1 Jan - 2 Jan 2026
High Tide Guesthouse PR

Enjoy a cozy space in a RV Camper w/hot tub, near beaches.

Enjoy a cozy space in a RV Camper w/hot tub, near beaches.
Lajas
10.0 out of 10, Exceptional, (10)
"Very peaceful place near la parguera, Guanica beaches and Yauco art murals and coffee shops. "
United States
Eileen
The price is €193
includes taxes & fees
4 Jan - 5 Jan 2026
Enjoy a cozy space in a RV Camper w/hot tub, near beaches.

Cozy 2BR house w/ AC & WiFi in Utuado near Tanama River

Cozy 2BR house w/ AC & WiFi in Utuado near Tanama River
Utuado
10.0 out of 10, Exceptional, (1)
The price is €183
includes taxes & fees
13 Jan - 14 Jan 2026
Cozy 2BR house w/ AC & WiFi in Utuado near Tanama River

Beach Apartment with Terrace in Playa Santa

Beach Apartment with Terrace in Playa Santa
Ensenada
10.0 out of 10, Exceptional, (1)
"This place had such a warm and welcoming environment. Beautifully decorated, tasteful, comfortable bed, roomy bathroom. The air conditioning was instant The place is magical. I loved it so much and will definitely return!"
United States
Lori W.
Beach Apartment with Terrace in Playa Santa

Boulevard 201

Boulevard 201
3.0 star property
Cárcel
8.0 out of 10, Very good, (1)
"Lugar centrico"
Mexico
Celinette
The price is €145
includes taxes & fees
10 Jan - 11 Jan 2026
Boulevard 201

Boqueron Beach and Country Cabins

Boqueron Beach and Country Cabins
2.5 star property
Boqueron
The price is €139
includes taxes & fees
11 Jan - 12 Jan 2026
Boqueron Beach and Country Cabins

Cozy studio near rest,malls,beaches, attractions, plenty of secure parking.

Cozy studio near rest,malls,beaches, attractions, plenty of secure parking.
Anasco
10.0 out of 10, Exceptional, (3)
"We enjoyed our stay very much. Host was very communicative & cordial. Loved the area & would consider staying again. "
United States
Nancy N.
The price is €148
includes taxes & fees
1 Jan - 2 Jan 2026
Cozy studio near rest,malls,beaches, attractions, plenty of secure parking.

HighTide Guesthouse Apartments, La Parguera

HighTide Guesthouse Apartments, La Parguera
La Parguera
9.4 out of 10, Exceptional, (3)
"The place was super cute, clean, and cozy. The place was in a quiet street, but still close enough to walk to the restaurants and night life. The host communicated all the necessary information in a tjmely manner, and didn't have any issues. I would definitely stay there again! "
United States
Maria
The price is €107
includes taxes & fees
1 Jan - 2 Jan 2026
HighTide Guesthouse Apartments, La Parguera

Camper Capacidad Hasta 6 Personas

Camper Capacidad Hasta 6 Personas
Cabo Rojo
The price is €117
includes taxes & fees
7 Jan - 8 Jan 2026
Camper Capacidad Hasta 6 Personas

Mayaguez spacious 3-bedroom Villa

Mayaguez spacious 3-bedroom Villa
Mayaguez
9.4 out of 10, Exceptional, (10)
"We stayed in Mayaguez to participate in the "Justas" activities and it was excellent. Good location, spacious property with parking. Thanks Gerard!"
United States
Monika O.
The price is €207
includes taxes & fees
9 Jan - 10 Jan 2026
Mayaguez spacious 3-bedroom Villa

Beach House with Pool in Playa Santa - Casa Perla

Beach House with Pool in Playa Santa - Casa Perla
Guánica
9.8 out of 10, Exceptional, (6)
"We went there for a basketball tournament so we spent most of our time out of the property but Ill definitely rent it again to be able to enjoy what it has to offer! Beautiful, beautiful place! "
United States
Taína T.
The price is €216
includes taxes & fees
18 Jan - 19 Jan 2026
Beach House with Pool in Playa Santa - Casa Perla

Centrally located , Family and Pet Friendly.

Centrally located , Family and Pet Friendly.
Cabo Rojo
10.0 out of 10, Exceptional, (2)
"This place was comfortable clean beautiful and close enough to drive in many directions. I would stay here again. Thank you my family also loved it!"
United States
Lorraine l.
The price is €198
includes taxes & fees
13 Jan - 14 Jan 2026
Centrally located , Family and Pet Friendly.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santana Hotel Reviews

Find out more about Santana

Everything you need to know about Santana holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santana holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santana holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Santana holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santana. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santana holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santana holiday rentals we have selected for you start as low as €95 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Santana rentals

At Expedia, we put the best Santana holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santana rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santana holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santana. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Are there holiday rentals in Santana?

Yes, there are holiday rentals close to the most popular sights in Santana, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that Santana has to offer?

Blue House Joyuda: This holiday home rental outside of Santana is located near the beach, and has an outdoor pool, a garden and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a fridge, a microwave and a coffee maker.

What can I see and do in Santana?

While exploring the area, visit family-friendly sights like Surf 'N Fun Water Park, or get outside and enjoy nature at Bosque Estatal de Maricao. In the wider area, you’ll find Church of Porta Coeli and Plaza San Pedro.

What are holiday rentals like in Santana?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santana. Holiday rentals feature amenities like laundry facilities and kitchens so you'll feel just like you're at home. If you're concerned about a sanitised environment, holiday rentals can offer a sense of seclusion away from shared hotel lifts and busy concierge desks while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a hotel, which makes a holiday rental a great choice for family trips.