Santana Holidays

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    Save up to €900 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top hotels in Santana

Arecibo Inn

Arecibo Inn

Road #2 km 67.2 Arecibo
Fully refundableReserve now, pay when you stay
€72
15 Sept - 16 Sept
includes taxes & fees
8/10 Very good! (1,028 reviews)
"Good place to stay."

Reviewed on 12 Sept 2026

Arecibo Inn
Hyatt Place Manati

Hyatt Place Manati

122 Carretera PR-2 Manati
Fully refundableReserve now, pay when you stay
€160
14 Sept - 15 Sept
includes taxes & fees
9.2/10 Wonderful! (1,049 reviews)
"It would have been convenient to have a microwave in the room."

Reviewed on 12 Sept 2026

Hyatt Place Manati
Hotel El Guajataca

Hotel El Guajataca

Carretera 2 Km. 103.8 Quebradillas
€90
15 Sept - 16 Sept
includes taxes & fees
8.4/10 Very good! (1,004 reviews)
"I’m a local and I just hope that tourists DO NOT think that this is how we do it down here in Puerto Rico! Property grounds are beautiful but the hotel is awful, starting from the service, to the rooms and to the food. People with poor work ethic, attitude and zero knowledge(or zero willingness to ..."

Reviewed on 12 Sept 2026

Hotel El Guajataca
See all 479 properties in Santana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in Santana

Private Adventure at Guayaney Spring

Adventure in Cave and the Guayaney Spring

€86
per adult
Adventure in Cave and the Guayaney Spring
tubing

Tanama River Cave Tubing

€95
per adult
90% of travellers recommend
Tanama River Cave Tubing
Full-Day Cueva Ventana, Indian Cave and Waterfall Adventure

3 in 1 Full Day Cueva Ventana, Indian Cave & Waterfall Adventure

€134
per adult
100% of travellers recommend
3 in 1 Full Day Cueva Ventana, Indian Cave & Waterfall Adventure
See all activities in Santana

Frequently asked questions

How much does a Santana holiday package cost?
You can snap up a holiday package to this popular destination on Expedia. However, how much your holiday to Santana costs will depend on the season, hotel choice and length of stay.
What are the cheapest months to go to Santana?
You're likely to find lower rates and better availability in July, August and October. Check out our cheap Santana holiday packages and you could land some excellent off-season deals.
How many days is enough for Santana?
Usually, a handful of days is enough to check out the major sights during your Santana holiday. But if you prefer to have time to relax or go on day trips, think about extending your trip.
How to find the best Santana package deals?
Finding a cheap Santana package deal is a breeze with Expedia. After you've entered your travel dates and destination under our "Packages" tab, set your budget, add a few filters and see what's available. You can tailor your search by "Popular locations," "Property type," "Guest rating" and more. Sort the results by "Price: low to high" to view the most affordable Santana package deals. Want a simple trick to get even more savings? Be flexible with your departure dates and consider going away on a weekday, when prices are usually lower.
Is it cheaper to book a Santana holiday as a package?
An Expedia holiday package could score you significant savings when compared to arranging flights and accommodation separately. Better still, you can customise your Santana escape to match your exact needs. Pick your preferred flight time, select the hotel type and add a rental car. Browse our bundle deals and find out how much you can save.
When to book a holiday package to Santana?
Land incredible bargains by booking your flights early with Expedia. If being spontaneous is more your style, take advantage of our last-minute deals for an impromptu Santana trip.
How to plan a trip to Santana?
  1. Choose the right time to travel: Your schedule, favourite season and the type of weather you like can all impact your decision on when to visit Santana.
  2. Figure out your budget: Make sure you have enough money to pay for everything from transportation and meals to airfares and activities. Your accommodation will probably be the biggest expense during your trip to Santana.
  3. Decide your trip length: Consider how long you want to spend discovering Santana. Plan your itinerary so you can get to all the attractions and experiences you're interested in at a comfortable pace.
  4. Bundle your hotel and flights: Epic destination, check. Length of stay, check. Now all that's left is to pick a Santana holiday package that brings all your bookings together.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.