Photo by Fabrice Récalt

São Tomé Island Hotel Guide - Business Hotels in São Tomé Island, São Tomé and Príncipe

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Check availability on São Tomé Island Business Hotels

Tonight
22 Dec - 23 Dec
Tomorrow
23 Dec - 24 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for São Tomé Island business-friendly hotels

View from property
Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection
4.0 star property
São Tomé
9.4 out of 10, Exceptional, (62)
"It’s a great resort, with friendly staff who "
United Kingdom
Kim
The price is €215
includes taxes & fees
4 Jan - 5 Jan 2026
Omali São Tomé – Principe Collection
Lobby sitting area
SH Boutique Hotel

SH Boutique Hotel

SH Boutique Hotel
3.5 star property
São Tomé
8.6 out of 10, Excellent, (10)
"Staff were very accommodating "
United States
Simon Peter
SH Boutique Hotel
Outdoor pool, pool umbrellas, pool loungers
Hotel Praia

Hotel Praia

Hotel Praia
3.5 star property
São Tomé
7.6 out of 10, Good, (17)
"Solid, basic hotel. "
United States
Jonathan
The price is €167
includes taxes & fees
23 Dec - 24 Dec
Hotel Praia
Coffee shop
Hotel Central

Hotel Central

Hotel Central
3.5 star property
São Tomé
8.2 out of 10, Very good, (24)
"Great value. Great location. Ok breakfast. Overall good value for money"
Norway
Elisabeth
Hotel Central
Poolside bar
Praia Accommodation

Praia Accommodation

Praia Accommodation
3.0 star property
São Tomé
7.2 out of 10, Good, (17)
"Great place to stay "
United States
Daniel
The price is €125
includes taxes & fees
20 Jan - 21 Jan 2026
Praia Accommodation
Bungalow
Guest House Quinta Natural

Guest House Quinta Natural

Guest House Quinta Natural
3.0 star property
Trindade
10.0 out of 10, Exceptional, (1)
Guest House Quinta Natural
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top São Tomé Island Hotel Reviews

Pestana São Tomé

Pestana São Tomé

10/10 Excellent
"Wonderful stay, great staff, easy, relaxing delightful."
alexander 5-night trip
Posted 13 days ago
Pestana São Tomé
Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

10/10 Excellent
"Staff was very friendly. Food was excellent. Room was clean and well kept."
christopher 5-night trip
Posted 3 weeks ago
Omali São Tomé – Principe Collection

Frequently asked questions

Why book your business-friendly hotel in São Tomé Island with Expedia?
We're here to help you find a great business-friendly hotel when work takes you away from home. From free parking and WiFi to gyms and on-site restaurants, our stays come with the conveniences you'll need to get the job done.
How can I find cheap business-friendly hotels in São Tomé Island?
Expedia can help you easily locate cheap business-friendly hotels in São Tomé Island. Simply go to our "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work comfortably, like included breakfast and free WiFi. You can also choose your budget and preferred star rating to keep costs under control.
What is there to do in São Tomé Island near my business-friendly hotel?
São Tomé Island has enough sights and experiences to keep you entertained for weeks, starting with Amelia Lagoon. São Nicolau Waterfall, Pico São Tomé and Bom Sucesso Botanical Garden are other impressive attractions. If your business trip keeps you hanging around town a little longer, Paroquia da Santissima Trindade and Batepa Church are great additions to your itinerary.