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Memphis Hotel Guide. Hotels in South Main, Memphis, United States of America

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Our top choices for South Main hotels

The Central Station Memphis, Curio Collection by Hilton

The Central Station Memphis, Curio Collection by Hilton
4.0 star property
South Main
9.0 out of 10, Wonderful, (1001)
"Wonderful staff and ambiance "
United States
Gabriela
The price is €112
includes taxes & fees
28 Dec - 29 Dec
The Central Station Memphis, Curio Collection by Hilton

ARRIVE Memphis

ARRIVE Memphis
4.0 star property
South Main
9.6 out of 10, Exceptional, (1003)
"Great stay "
United States
LaKera
The price is €174
includes taxes & fees
1 Jan - 2 Jan 2026
ARRIVE Memphis

Hotel Pontotoc

Hotel Pontotoc
2.0 star property
South Main
10.0 out of 10, Exceptional, (3)
"Beautiful hotel, great bar, spacious rooms. Excellent!!!"
United States
Cheryl
The price is €261
includes taxes & fees
28 Dec - 29 Dec
Hotel Pontotoc

The Rambler

The Rambler
4.0 star property
South Main
9.2 out of 10, Wonderful, (527)
"Walkable, neat spot."
United States
Teresa
The price is €136
includes taxes & fees
22 Dec - 23 Dec
The Rambler

Drury Inn & Suites Memphis Southaven

Drury Inn & Suites Memphis Southaven
3.0 star property
19.9 km from South Main
9.2 out of 10, Wonderful, (1001)
"Friendly staff, clean room, happy hour food & drink"
United States
Kathleen
The price is €95
includes taxes & fees
27 Dec - 28 Dec
Drury Inn & Suites Memphis Southaven

Big Cypress Lodge

Big Cypress Lodge
5.0 star property
Pinch District, 2.3 km from South Main
9.0 out of 10, Wonderful, (1720)
"Everything was great! It’s a very relaxing hotel to visit but also has lots to do in the hotel and surrounding areas. 10/10 we are planning to visit again! "
United States
Albina
The price is €237
includes taxes & fees
21 Jan - 22 Jan 2026
Big Cypress Lodge

Hampton Inn & Suites Memphis-Beale Street

Hampton Inn & Suites Memphis-Beale Street
2.5 star property
Downtown Memphis, 0.9 km from South Main
8.6 out of 10, Excellent, (1227)
"Excellent hotel in a great location "
United States
Ralph
The price is €119
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn & Suites Memphis-Beale Street

Hyatt Centric Beale Street Memphis

Hyatt Centric Beale Street Memphis
4.0 star property
Downtown Memphis, 0.7 km from South Main
8.8 out of 10, Excellent, (1407)
"Clean room, friendly staff "
United States
Phil
The price is €129
includes taxes & fees
24 Dec - 25 Dec
Hyatt Centric Beale Street Memphis

La Quinta Inn & Suites by Wyndham Memphis Airport Graceland

La Quinta Inn & Suites by Wyndham Memphis Airport Graceland
3.0 star property
8.8 km from South Main
7.4 out of 10, Good, (2210)
"Room was clean the stay was very pleasant"
United States
Tammy
The price is €56
includes taxes & fees
28 Dec - 29 Dec
La Quinta Inn & Suites by Wyndham Memphis Airport Graceland

The Westin Memphis Beale Street

The Westin Memphis Beale Street
4.0 star property
Downtown Memphis, 0.7 km from South Main
8.8 out of 10, Excellent, (1004)
"Room and location was very nice. "
United States
DEREX
The price is €156
includes taxes & fees
18 Jan - 19 Jan 2026
The Westin Memphis Beale Street

Comfort Inn Memphis Downtown

Comfort Inn Memphis Downtown
2.5 star property
Downtown Memphis, 1.6 km from South Main
8.8 out of 10, Excellent, (1003)
"Great hotel "
United States
Andre
The price is €93
includes taxes & fees
28 Dec - 29 Dec
Comfort Inn Memphis Downtown

Hyatt Place Memphis/Wolfchase Galleria

Hyatt Place Memphis/Wolfchase Galleria
3.0 star property
Wolfchase, 24.7 km from South Main
9.0 out of 10, Wonderful, (1378)
"Great breakfast selection, cleanliness "
United States
JACQUE
The price is €100
includes taxes & fees
4 Jan - 5 Jan 2026
Hyatt Place Memphis/Wolfchase Galleria

Holiday Inn Express & Suites Memphis Arpt Elvis Presley Blv by IHG

Holiday Inn Express & Suites Memphis Arpt Elvis Presley Blv by IHG
2.5 star property
Whitehaven, 9.2 km from South Main
8.2 out of 10, Very good, (1002)
"The Staff and everything from rooms to secured parking was top notch . "
United States
Pamela
The price is €104
includes taxes & fees
26 Dec - 27 Dec
Holiday Inn Express & Suites Memphis Arpt Elvis Presley Blv by IHG

Hu. Hotel

Hu. Hotel
3.5 star property
Downtown Memphis, 1.3 km from South Main
8.4 out of 10, Very good, (1627)
"Great hotel and location "
United States
Holiday
The price is €93
includes taxes & fees
27 Dec - 28 Dec
Hu. Hotel

Residence Inn by Marriott Memphis Downtown

Residence Inn by Marriott Memphis Downtown
3.0 star property
Downtown Memphis, 1.2 km from South Main
9.2 out of 10, Wonderful, (899)
"Well run hotel."
United States
Robert
The price is €124
includes taxes & fees
3 Jan - 4 Jan 2026
Residence Inn by Marriott Memphis Downtown

Best Western Plus Galleria Inn & Suites

Best Western Plus Galleria Inn & Suites
2.5 star property
Wolfchase, 26.8 km from South Main
8.0 out of 10, Very good, (1005)
"Very nice place to stay."
United States
Jack
The price is €80
includes taxes & fees
5 Jan - 6 Jan 2026
Best Western Plus Galleria Inn & Suites

Hampton Inn & Suites Memphis-Wolfchase Galleria

Hampton Inn & Suites Memphis-Wolfchase Galleria
2.5 star property
Wolfchase, 25.3 km from South Main
8.8 out of 10, Excellent, (857)
"I loved my stay"
United States
beatrice
The price is €98
includes taxes & fees
10 Jan - 11 Jan 2026
Hampton Inn & Suites Memphis-Wolfchase Galleria

The Guest House at Graceland

The Guest House at Graceland
4.0 star property
Whitehaven, 10 km from South Main
9.4 out of 10, Exceptional, (2854)
"Large room, excellent staff and shuttle service was prompt and easy "
United States
cathy weaver
The price is €239
includes taxes & fees
23 Dec - 24 Dec
The Guest House at Graceland

La Quinta Inn & Suites by Wyndham Memphis Downtown

La Quinta Inn & Suites by Wyndham Memphis Downtown
3.0 star property
Downtown Memphis, 1.3 km from South Main
9.2 out of 10, Wonderful, (1300)
"Great stay! Polite,friendly staff. Very clean!!"
United States
Nicholas
The price is €120
includes taxes & fees
25 Dec - 26 Dec
La Quinta Inn & Suites by Wyndham Memphis Downtown

La Quinta Inn & Suites by Wyndham Olive Branch

La Quinta Inn & Suites by Wyndham Olive Branch
2.5 star property
26.1 km from South Main
9.4 out of 10, Exceptional, (226)
"Clean rooms, large shower, friendly, helpful staff."
United States
Janice
The price is €89
includes taxes & fees
19 Jan - 20 Jan 2026
La Quinta Inn & Suites by Wyndham Olive Branch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Main

Find the best South Main areas for the activities you enjoy most.

Downtown Memphis

Downtown Memphis is a destination visitors seek out for its ample dining options, fascinating museums and great live music. You might also want to check out attractions like Statue of Elvis or Orpheum Theatre while you're exploring the neighbourhood.

East Memphis

Travellers to East Memphis praise its popular shops. If you've got some more time to explore, be sure to stop by Leftwich Tennis Center and Theatre Memphis.

Midtown

Theatres, live music and museums are some highlights of Midtown. Make a stop by Minglewood Hall or Memphis Brooks Museum of Art while you're exploring.

Whitehaven

The ample dining options and great live music are top of the list for many visitors to Whitehaven. A stop by Graceland or Tri-State Bank of Memphis might round out your trip.

North Memphis

Visitors to North Memphis like its bars and churches, and Burkle Estate is a sight worth a stop.

Top South Main Hotel Reviews

Frequently asked questions

What is South Main like?
You'll be sure to have fun exploring Memphis's South Main neighbourhood. Make sure that you visit Blues Hall of Fame Museum and Railroad & Trolley Museum as part of your South Main travel plans.
What's a favourite place to stay in South Main?
Based on Expedia customer reviews, The Cottage in the Historic South Main Arts District, Walk Everywhere Downtown is the highest ranked property in South Main. This guest house is a short 12-minute walk from Beale Street, and it offers private decks and free WiFi. Other top choices in the neighbourhood include ARRIVE Memphis and The Central Station Memphis, Curio Collection by Hilton.
How many hotels can I expect to find in South Main?
Expedia has 47 hotels and other accommodation options in South Main to choose from, making this an ideal home base for exploring the greater Memphis area.
If I need to cancel my hotel reservation in South Main, will I receive a refund?
Yes! Most hotel bookings are refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals available in South Main.
What are the top things to see and do in South Main?
Create some family memories with a visit to Blues Hall of Fame Museum or Railroad & Trolley Museum while you're in South Main. When you're sightseeing in Memphis, National Civil Rights Museum and Lorraine Motel are also worth a stop.
How can I get around South Main and the greater Memphis area?
To venture out of town, take a train from Memphis Central Station.