Photo by Michael Schuier

Southeast Iowa Hotel Guide - Business Hotels in Southeast Iowa, United States of America

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Check availability on Southeast Iowa Business Hotels

Tonight
29 Dec - 30 Dec
Tomorrow
30 Dec - 31 Dec
This weekend
2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

Our top choices for Southeast Iowa business-friendly hotels

Free daily on-the-go breakfast
AmericInn by Wyndham Mount Pleasant

AmericInn by Wyndham Mount Pleasant

AmericInn by Wyndham Mount Pleasant
2.0 star property
Mount Pleasant
8.4 out of 10, Very good, (540)
"Polite staff and very comfortable bed"
United States
Stasia
The price is €72
includes taxes & fees
4 Jan - 5 Jan 2026
AmericInn by Wyndham Mount Pleasant
Terrace/patio
Cobblestone Inn & Suites - Fort Madison

Cobblestone Inn & Suites - Fort Madison

Cobblestone Inn & Suites - Fort Madison
2.5 star property
Fort Madison
9.4 out of 10, Exceptional, (649)
"Really nice hotel, especially when it's below zero and snowing. "
United States
David
The price is €63
includes taxes & fees
31 Dec - 1 Jan 2026
Cobblestone Inn & Suites - Fort Madison
Exterior
Best Western Mt. Pleasant Inn

Best Western Mt. Pleasant Inn

Best Western Mt. Pleasant Inn
2.5 star property
Mount Pleasant
8.2 out of 10, Very good, (780)
"Very friendly. "
United States
Barry
The price is €69
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Mt. Pleasant Inn
Free daily buffet breakfast
Hampton Inn Keokuk

Hampton Inn Keokuk

Hampton Inn Keokuk
2.5 star property
Keokuk
8.8 out of 10, Excellent, (642)
"Very good stay. I’ll definitely stay there again "
United States
Tammy
The price is €93
includes taxes & fees
9 Jan - 10 Jan 2026
Hampton Inn Keokuk
Suite, 1 King Bed with Sofa bed, Non Smoking
Quality Inn & Suites Keokuk North

Quality Inn & Suites Keokuk North

Quality Inn & Suites Keokuk North
2.5 star property
Keokuk
8.4 out of 10, Very good, (752)
"Decent room. Good breakfast. "
United States
Matthew
The price is €76
includes taxes & fees
11 Jan - 12 Jan 2026
Quality Inn & Suites Keokuk North
Double Room, 2 Double Beds
Super 8 by Wyndham Mt Pleasant

Super 8 by Wyndham Mt Pleasant

Super 8 by Wyndham Mt Pleasant
2.0 star property
Mount Pleasant
8.2 out of 10, Very good, (842)
"Good stay , no issues "
United States
John
The price is €72
includes taxes & fees
21 Jan - 22 Jan 2026
Super 8 by Wyndham Mt Pleasant
Exterior
Hampton Inn & Suites Burlington

Hampton Inn & Suites Burlington

Hampton Inn & Suites Burlington
2.5 star property
Burlington
9.6 out of 10, Exceptional, (311)
"Clean room, nice staff "
United States
Michael
The price is €132
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Burlington
Front of property – evening/night
Fairfield Inn & Suites by Marriott Burlington

Fairfield Inn & Suites by Marriott Burlington

Fairfield Inn & Suites by Marriott Burlington
2.5 star property
Burlington
8.4 out of 10, Very good, (295)
"It was quiet & they gave us water, when we checked in, was hot out, so that was so nice!"
United States
Loren
The price is €119
includes taxes & fees
16 Jan - 17 Jan 2026
Fairfield Inn & Suites by Marriott Burlington
Reception
Quality Inn & Suites Mount Pleasant

Quality Inn & Suites Mount Pleasant

Quality Inn & Suites Mount Pleasant
2.5 star property
Mount Pleasant
8.0 out of 10, Very good, (116)
"The staff were absolutely great!!"
United States
Jacob
The price is €64
includes taxes & fees
22 Jan - 23 Jan 2026
Quality Inn & Suites Mount Pleasant
Free daily buffet breakfast
Holiday Inn Express Hotel & Suites Burlington by IHG

Holiday Inn Express Hotel & Suites Burlington by IHG

Holiday Inn Express Hotel & Suites Burlington by IHG
2.5 star property
Burlington
8.6 out of 10, Excellent, (467)
"Friendly staff and very clean hotel"
United States
Julie
The price is €122
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Hotel & Suites Burlington by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southeast Iowa Hotel Reviews

AmericInn by Wyndham West Burlington

AmericInn by Wyndham West Burlington

10/10 Excellent
"Very nice and clean room"
Karen 1-night trip
Posted 5 days ago
AmericInn by Wyndham West Burlington

Frequently asked questions

How much do business-friendly hotels in Southeast Iowa cost?
Expect to pay between €63 and €132 per night for business-friendly hotels in Southeast Iowa. Awesome deals on stays that are suitable for corporate travellers are a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Southeast Iowa?
Southeast Iowa has 17 business-friendly hotels to choose from. Whether you're attending a conference or working remotely, these properties are equipped with everything you need to be productive.
Why book your business-friendly hotel in Southeast Iowa with Expedia?
Expedia will help you find a fabulous business-friendly hotel when work takes you on the road. From free WiFi and parking to gyms and spas, our stays come with all you'll need to settle that big contract.
How can I find cheap business-friendly hotels in Southeast Iowa?
Expedia can help you easily find cheap business-friendly hotels in Southeast Iowa. Simply head to the "traveller experience" filter and click on "business friendly." This will show you properties with amenities designed to help you work comfortably and efficiently, like included breakfast and free WiFi. You can also choose your hotel star rating and budget to keep costs down.
What is there to do in Southeast Iowa near my business-friendly hotel?
You'll find tons of attractions to see during your time in Southeast Iowa. If you've planned a couple of nights in Nauvoo, Rheinberger House Museum is a must-see.