Holiday Homes in Southeast Iowa

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks
In one month
In two months

Featured Holiday Homes in Southeast Iowa and around

Riverside Waterfront on the Mississippi River

9.6 out of 10, Exceptional, (15)
"I would stay again for sure. Very nice place in a great location. "
The price is €252
includes taxes & fees
17 Aug - 18 Aug
Riverside Waterfront on the Mississippi River

Golf and Stay house is next to Twin Oaks Golf Course. Lovely 9 hole golf course.

9.6 out of 10, Exceptional, (13)
"Very nice house , as advertised. Will stay again."
The price is €144
includes taxes & fees
9 Aug - 10 Aug
Golf and Stay house is next to Twin Oaks Golf Course. Lovely 9 hole golf course.

Voted "Best Location" and "Most Comfortable".....

10.0 out of 10, Exceptional, (40)
"Rooms were absolutely beautiful. We really enjoyed our stay and will probably come back next year"
The price is €138
includes taxes & fees
30 Aug - 31 Aug
Voted "Best Location" and "Most Comfortable".....

The Artist's Bungaloo

10.0 out of 10, Exceptional, (3)
"Everything about this property went very smoothly. The host and manager were very accommodating for our special requests and the house was very clean.This location was central to everything Fairfield has to offer."
The price is €196
includes taxes & fees
8 Sept - 9 Sept
The Artist's Bungaloo

Finn's Hideaway - Secluded family home with river view

10.0 out of 10, Exceptional, (34)
"I loved the house and the owner was very helpful with communication."
Finn's Hideaway - Secluded family home with river view

Mayor's Manor - with everything you need in a homebase get away. Pet friendly.

10.0 out of 10, Exceptional, (13)
"We had a wonderful weekend, quaint little town tucked into the Mississippi Valley. Neighbors were welcoming, enjoyed this stay."
Mayor's Manor - with everything you need in a homebase get away. Pet friendly.

Historic 1840s Lamoreaux House / Modern Addition

9.8 out of 10, Exceptional, (15)
"Had a wonderful time at the Vrbo and enjoyed the towns of Ft. Madison and Nauvoo. "
The price is €288
includes taxes & fees
11 Aug - 12 Aug
Historic 1840s Lamoreaux House / Modern Addition

Cozy House

10.0 out of 10, Exceptional, (3)
"I loved it! We were greeted by the host and their dog (who’s friendly as ever!) upon arrival and everything went perfectly smooth from there. The blankets were honestly the best part, LOL! We were all obsessed! Perfect little spot to stay right off the highway in a quiet neighborhood. Will definitely consider it again in the future if I need somewhere to stay near here again! "
The price is €154
includes taxes & fees
20 Aug - 21 Aug
Cozy House

Nauvoo Windmill Farmhouse 10-12 people

10.0 out of 10, Exceptional, (7)
"Our family had a wonderful weekend at the Windmill Farmhouse! "
The price is €184
includes taxes & fees
9 Aug - 10 Aug
Nauvoo Windmill Farmhouse 10-12 people

Oquawka Cottage With River View

9.6 out of 10, Exceptional, (7)
"We thoroughly enjoyed our recent stay highlighted by a clean house and comfortable beds with a well stocked kitchen for our long weekend in Henderson County. Mindi was very responsive and speedy checkin. Cottage located within sight of the Mississippi and we watched boat traffic easily. We would easily stay again."
The price is €170
includes taxes & fees
14 Aug - 15 Aug
Oquawka Cottage With River View

Family Home in Carthage

10.0 out of 10, Exceptional, (12)
"Great location-"
The price is €200
includes taxes & fees
8 Sept - 9 Sept
Family Home in Carthage

Idyllic Biggsville Vacation Rental: 10 Mi to River

The price is €181
includes taxes & fees
9 Aug - 10 Aug
Idyllic Biggsville Vacation Rental: 10 Mi to River

Family friendly 3 bedroom home in Kahoka MO

9.0 out of 10, Wonderful, (2)
"The place was exactly as advertised and perfect for our stay. Becca was so helpful. We forgot something and she mailed it out to us right away. I recommend anyone looking for a place to stay, dont hesitate to book with Becca."
The price is €157
includes taxes & fees
15 Aug - 16 Aug
Family friendly 3 bedroom home in Kahoka MO

Charming 3-bedroom building with WiFi, AC in enjoyable West Point

2.0 star property
10.0 out of 10, Exceptional, (2)
"I was in the area on a hunting trip. This is a great cabin and I couldn't ask for better communication with the host. A"
Charming 3-bedroom building with WiFi, AC in enjoyable West Point

Large home with 35+ guests : 10 Minutes from Nauvoo

9.8 out of 10, Exceptional, (12)
"We stayed with our family of 30 people, including 15 grandkids. There are only 4 private bedrooms, but the endless bunk beds in the basement made such a FUN sleeping place! The property was even better than we had imagined, with a gorgeous view of the Mississippi River and acres of grass for playing football and other games. We stayed there in June and enjoyed the magic of fireflies at night, but the favorite activity was swimming in the POOL! It was a lovely place to stay."
Large home with 35+ guests : 10 Minutes from Nauvoo

Peaceful, spacious 4 bedroom house in the country - Gazebo/Pond

10.0 out of 10, Exceptional, (20)
"Nice place to stay with family"
Peaceful, spacious 4 bedroom house in the country - Gazebo/Pond

"A Taste of Heaven" 3-bedroom house in Fairfield with WiFi, A/C & east entrance

2.0 star property
10.0 out of 10, Exceptional, (6)
"Relaxing stay in the country yet within 15 minutes of Fairfield. Very clean & comfortable!. We will definitely stay again when in the area!"
"A Taste of Heaven" 3-bedroom house in Fairfield with WiFi, A/C & east entrance

Riverview Orchard 2: Master Suite Studio Style

8.0 out of 10, Very good, (2)
"Private and very clean location. King bed was SOOO comfortable to relax and sleep in. Roomy bathroom. Just like staying in a fancy hotel. If was staying longer would have preferred more than a mini fridge. Since no kitchen we made due with doing dishes in shower & sink with a small wash tub. Possibly a small utility sink in laundry storage room would be beneficial. Brought an electric griddle to make our food a few times. Otherwise a perfect location with nice views on both of the spacious...
The price is €149
includes taxes & fees
9 Aug - 10 Aug
Riverview Orchard 2: Master Suite Studio Style

Recently remodeled Nauvoo home, 7 acres on the river

10.0 out of 10, Exceptional, (35)
"The property was just as expected and more. Very clean and well stocked. Great beds and bathroom. We enjoyed the home very much."
Recently remodeled Nauvoo home, 7 acres on the river

Experience Beautiful Pioneer Home In Nauvoo!

10.0 out of 10, Exceptional, (74)
"We had a wonderful anniversary trip to Nauvoo. The historic and quaint Mix House added some period charm to our stay. While the house retains much of its 19th century charm, it has the modern conveniences needed for a relaxing stay. It may have been the off season, but food and meal choices were limited in Nauvoo itself. We were grateful for the items we ordered from The Apron Bake Shoppe."
The price is €335
includes taxes & fees
2 Sept - 3 Sept
Experience Beautiful Pioneer Home In Nauvoo!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Southeast Iowa Hotel Reviews