Photo by Jake Blucker

Southeast Ohio Hotel Guide - Business Hotels in Southeast Ohio, Ohio

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Southeast Ohio Business Hotels

Tonight
25 Dec - 26 Dec
Tomorrow
26 Dec - 27 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for Southeast Ohio business-friendly hotels

Free full breakfast
Quality Inn & Suites Zanesville City Center

Quality Inn & Suites Zanesville City Center

Quality Inn & Suites Zanesville City Center
2.5 star property
Zanesville
8.8 out of 10, Excellent, (512)
"Friendly staff. Good breakfast. Older but clean hotel. Great bed."
United States
Karen
The price is €83
includes taxes & fees
2 Jan - 3 Jan 2026
Quality Inn & Suites Zanesville City Center
Terrace/patio
The Lodge at Hocking College

The Lodge at Hocking College

The Lodge at Hocking College
2.5 star property
Nelsonville
9.0 out of 10, Wonderful, (838)
"Great place!"
United States
Haoting
The price is €57
includes taxes & fees
28 Dec - 29 Dec
The Lodge at Hocking College
Free full breakfast
HOLIDAY INN EXPRESS & SUITES ZANESVILLE NORTH by IHG

HOLIDAY INN EXPRESS & SUITES ZANESVILLE NORTH by IHG

HOLIDAY INN EXPRESS & SUITES ZANESVILLE NORTH by IHG
2.5 star property
Zanesville
9.2 out of 10, Wonderful, (567)
"The rooms were very clean and the breakfast was pretty good too. It was my first time having access to a pancake maker."
United States
ALLEN
The price is €92
includes taxes & fees
11 Jan - 12 Jan 2026
HOLIDAY INN EXPRESS & SUITES ZANESVILLE NORTH by IHG
Pool
Christopher Inn and Suites

Christopher Inn and Suites

Christopher Inn and Suites
2.5 star property
Chillicothe
9.0 out of 10, Wonderful, (1124)
"Friendly service, clean room, great breakfast, nice area!"
United States
Sandra
The price is €131
includes taxes & fees
27 Dec - 28 Dec
Christopher Inn and Suites
Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Walk-in Shower;Larger Room)
Best Western River Cities

Best Western River Cities

Best Western River Cities
2.5 star property
Russell
8.6 out of 10, Excellent, (428)
"Staff was nice. Scott helped us out as well as the lady that works overnights. The room was simple and clean. Breakfast was good for what it was. Stayed here last year and will stay next year for Thanksgiving and Christmas as well when we visit family. "
United States
Lindsay
The price is €98
includes taxes & fees
28 Dec - 29 Dec
Best Western River Cities
Property amenity
Fairfield Inn & Suites Cambridge

Fairfield Inn & Suites Cambridge

Fairfield Inn & Suites Cambridge
2.5 star property
Cambridge
9.6 out of 10, Exceptional, (835)
"Clean, comfy, nice breakfast and helpful staff."
United States
katherine
The price is €109
includes taxes & fees
26 Dec - 27 Dec
Fairfield Inn & Suites Cambridge
Reception
Hampton Inn Zanesville

Hampton Inn Zanesville

Hampton Inn Zanesville
2.5 star property
Zanesville
8.6 out of 10, Excellent, (534)
"Had the best time and the staff was so helpful with everything! "
United States
Penny
The price is €82
includes taxes & fees
30 Dec - 31 Dec
Hampton Inn Zanesville
Ballroom
The Blennerhassett Hotel

The Blennerhassett Hotel

The Blennerhassett Hotel
3.5 star property
Parkersburg
9.4 out of 10, Exceptional, (1005)
"Very nice hotel, nice big clean rooms"
United States
Cory
The price is €132
includes taxes & fees
31 Dec - 1 Jan 2026
The Blennerhassett Hotel
Lobby
Sleep Inn & Suites Parkersburg - Mineral Wells

Sleep Inn & Suites Parkersburg - Mineral Wells

Sleep Inn & Suites Parkersburg - Mineral Wells
2.5 star property
Parkersburg
8.6 out of 10, Excellent, (451)
"This is oir home away from home when we go backnto visit our grandkids.We have always been treated great, the rooms have always been clean, the beds are always comfortable. We've stayed at the other high dollar gotels in the area and they are rude, the breakfast sucks, the rooms arent any cleaner, and the beds are anymore softer, do t waste your money on the other hotels, stay at the sleep inn."
United States
scott
The price is €67
includes taxes & fees
28 Dec - 29 Dec
Sleep Inn & Suites Parkersburg - Mineral Wells
Exterior
Microtel Inn & Suites By Wyndham New Martinsville

Microtel Inn & Suites By Wyndham New Martinsville

Microtel Inn & Suites By Wyndham New Martinsville
2.5 star property
New Martinsville
9.2 out of 10, Wonderful, (143)
"Great staff. We enjoy staying here They have Thanksgiving Dinner day before Thanksgiving for all. Very friendly . Like family. "
United States
Frank
The price is €112
includes taxes & fees
27 Dec - 28 Dec
Microtel Inn & Suites By Wyndham New Martinsville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Southeast Ohio Hotel Reviews

Ohio University Inn & Conference Center

Ohio University Inn & Conference Center

10/10 Excellent
"Great location. Clean rooms and the restaurant will make you want to come back for more. Wonderful stay. "
Tim 1-night trip
Posted 3 days ago
Ohio University Inn & Conference Center

Frequently asked questions

How much do business-friendly hotels in Southeast Ohio cost?
Rates for business hotels in Southeast Ohio range between €57 and €132 per night. No matter your budget, Expedia is here to help you find the right place to get your work done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Southeast Ohio?
Southeast Ohio has multiple business-friendly hotels with a total average guest review rating of 8.9. Have a work event in Wheeling? Hampton Inn Wheeling is a 3-star stay that's highly recommended by corporate travellers and features a barbecue grill and a steam room. Another suitable option for a business trip is Hawthorn Suites by Wyndham Wheeling at the Highlands. Also in Wheeling, it has a 3.5-star rating and amenities such as premium bedding and a down comforter.
How many business-friendly hotels are there in Southeast Ohio?
When your next work trip takes you around Southeast Ohio, there are 130 business-friendly hotels to choose from.
Why book your business-friendly hotel in Southeast Ohio with Expedia?
Here at Expedia, our job is to help you land the ideal stay at the right price. From deluxe, corporate-friendly getaways to affordable motor inns filled with all the amenities you need, you'll have your next work trip planned in just a few clicks.
How can I find cheap business-friendly hotels in Southeast Ohio?
When work takes you on the road in Southeast Ohio, our "business friendly" filter will help you find the right hotel. From WiFi to workspaces and meeting rooms, they have the amenities you need to get down to business. You can also narrow your search by your preferred star rating and budget to view the cheapest accommodation.
What is there to do in Southeast Ohio near my business-friendly hotel?
There are countless things to put on your to-do list in Southeast Ohio. If you're on your way to Wheeling, be sure to look around Capitol Theatre, Heritage Port Amphitheatre and Scottish Rite Cathedral. Packing your bags for Logan? R Adventure Park, Bowen House Cultural Arts and Education Centre and Brass Ring Golf Club are popular attractions here.

Explore a world of travel with Expedia