Clayton
St. Louis
Visit Clayton
Top hotels in Clayton
Clayton Plaza Hotel & Extended Stay
This is an older property, but very clean, comfortable, spacious and convenient to downtown Clayton. Parking was convenient and free on the weekend. Breakfast was better than average, with chef-made omelets and waffles.
Reviewed on 11 Mar 2026
The Ritz-Carlton, St. Louis
Le Méridien St. Louis Clayton
Pool was closed for the season so didn’t get to enjoy but had wonderful view from our room. Staff and hotel was clean. Room was a little small but nice.
Reviewed on 5 Mar 2026
Hampton Inn & Suites Clayton/St. Louis-Galleria Area
We've stayed in this hotel several times. The rooms are clean and comfortable, and we'll return here in the future when we travel to St. Louis.
Reviewed on 9 Mar 2026
21C Museum Hotel St Louis
Such a cool hotel I love the museum on the second floor so interesting and all the penguins food is great restaurants great everything just what a great stay very unique but very quiet very cozy love everything about it. Can’t wait to stay at the other ones.
Reviewed on 11 Mar 2026
Drury Plaza Hotel St. Louis at the Arch
Very nice staff and great atmosphere. Quietest hotel room i have ever stayed in
Reviewed on 10 Mar 2026
Other neighbourhoods around Clayton
University City
Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.
Dogtown
When in Dogtown, you can plan a visit to St. Louis Zoo and St. Louis Art Museum, some noteworthy sights in the nearby area.
Ladue
Ladue is well liked for its restaurants and churches. If you're hoping to see more of the larger area, Saint Louis Galleria Mall and St. Louis Art Museum are some interesting sights nearby to check out.
The Hill
While The Hill isn't home to many top sights, St. Louis Science Center and Missouri Botanical Gardens and Arboretum are some notable places to visit nearby.
Southwest Garden
While Southwest Garden may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
