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Experience the perfect blend of comfort and convenience at Hampton Inn & Suites St. Louis/South I-55. Start your day with a breakfast buffet, unwind by the lobby fireplace or take a refreshing dip in the indoor pool.
Reviews
9.6 out of 10
Exceptional
Popular amenities
The current price is €129
includes taxes & fees
31 Aug - 1 Sept
Room options
Available filters for rooms
Showing 7 of 7 rooms
View all photos for Two Queen Beds, Non-Smoking, Accessible

Two Queen Beds, Non-Smoking, Accessible
9.6 out of 10
Exceptional
(25 reviews)
Highlights
Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Separate bedroom
Blackout curtains
Shower/bath combination
View all photos for Room

Room
9.6 out of 10
Exceptional
(14 reviews)
Highlights
Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Separate bedroom
Blackout curtains
Hairdryer
View all photos for One King Bed, Non-Smoking, Accessible

One King Bed, Non-Smoking, Accessible
9.8 out of 10
Exceptional
(18 reviews)
Highlights
Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Separate bedroom
Blackout curtains
Shower/bath combination
View all photos for Studio, Accessible, Non Smoking

Studio, Accessible, Non Smoking
9.0 out of 10
Wonderful
(4 reviews)
Highlights
Separate sitting area
Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Blackout curtains
Sofa bed - double
View all photos for Room

Room
9.8 out of 10
Exceptional
(34 reviews)
Highlights
Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Separate bedroom
Blackout curtains
Hairdryer
View all photos for Room

Room
10.0 out of 10
Exceptional
(2 reviews)
Highlights
Separate sitting area
Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Blackout curtains
Sofa bed - double
View all photos for Room

Room
9.6 out of 10
Exceptional
(4 reviews)
Highlights
Separate sitting area
Air conditioning
Connecting rooms available
Free cots/infant beds
Fridge
LCD TV
Separate bedroom
Blackout curtains
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The price is €117
includes taxes & fees
31 Aug - 1 Sept
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About the area
St. Louis is home to Hampton Inn & Suites St. Louis/South I-55. St. Louis Zoo is a popular attraction and the area's natural beauty can be seen at Mississippi River and Forest Park. Grant's Farm and Swing-A-Round Fun Town are also worth visiting.

4200 Midamerica Lane, St. Louis, MO, 63129
What's nearby
- Barnes Jewish South Campus - 5 min walk - 0.4 km
- Mercy Hospital South - 5 min drive - 4.6 km
- Grant's Farm - 11 min drive - 9.4 km
- River City Casino - 11 min drive - 12.1 km
- Magic House - St. Louis Children's Museum - 13 min drive - 16.8 km
Getting around
Restaurants
- McDonald's - 3 min drive
- Burger King - 10 min walk
- Starbucks - 9 min walk
- Buffalo Wild Wings - 5 min drive
- Popeyes Louisiana Kitchen - 3 min walk
About this property
Hampton Inn & Suites St. Louis/South I-55
Property amenities
Room amenities
Policies
Important information
Optional extras
- Pet fee: USD 75 per accommodation, per stay
- Service animals are exempt from fees
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
This property is managed by a professional host. The provision of housing is linked to their trade, business or profession.
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorise the guest's credit card prior to arrival.
If you cancel your booking, you'll be subject to the host's cancellation policy. In accordance with EU regulations about consumer rights, property booking services are not subject to the right of withdrawal.
We should mention
Pool access available from 8 AM to 10 PM
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
Children under 13 years old are not allowed in the swimming pool or fitness facility without adult supervision
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)
Property is also known as
Hampton Inn I-55
Hampton Inn I-55 St.Louis
Hampton Inn South St.Louis
Hampton Inn St.Louis I-55
Hampton Inn St.Louis South
Hampton Inn St.Louis South I-55
Hampton Inn St.Louis South I-55 Hotel
Hampton Inn St.Louis South I-55 Hotel St. Louis
Hampton Inn St.Louis South I-55 St. Louis
St.Louis South
Hampton Inn Suites St.Louis South at I 55
Frequently asked questions
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Hampton Inn & Suites St. Louis/South I-55 Reviews
Reviews
9.6
Exceptional
9.8/10
Cleanliness
9.8/10
Staff & service
9.4/10
Amenities
9.6/10
Property conditions & facilities
9.2/10
Eco-friendliness
Reviews
17 Jun 2025
Liked: Cleanliness, amenities, property conditions & facilities
Stayed 2 nights in Jun 2025
10/10 Excellent
Brittany
27 Jul 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Brittany
Stayed 1 night in Jul 2025
10/10 Excellent
Peter
6 Aug 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Peter
Stayed 1 night in Jul 2025
10/10 Excellent
Fannie
21 Aug 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Fannie
Stayed 3 nights in Aug 2025
10/10 Excellent
Angie
12 May 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great stay
Angie
Stayed 2 nights in Feb 2025
10/10 Excellent
Sandro
16 Jun 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Sandro
Stayed 2 nights in Jun 2025
10/10 Excellent
Franklin
31 Mar 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Franklin
Stayed 1 night in Mar 2025
10/10 Excellent
Ralph
1 Jul 2025
Ralph
Stayed 1 night in Jun 2025
8/10 Good
Ellene
19 Jul 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Ellene
Stayed 5 nights in Jul 2025
10/10 Excellent
Michael
29 May 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Quick trip
Michael
Stayed 1 night in May 2025
10/10 Excellent
Angela
21 Mar 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Angela
Stayed 1 night in Mar 2025
10/10 Excellent
Richard
20 Apr 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Perfect
Richard
Stayed 2 nights in Apr 2025
10/10 Excellent
Beverly
22 Jun 2025
Liked: Cleanliness, amenities, property conditions & facilities
Beverly
Stayed 1 night in Jun 2025
10/10 Excellent
Mike
16 May 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Mike
Stayed 2 nights in Mar 2025
8/10 Good
Michael
18 Jan 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Michael
Stayed 4 nights in Dec 2024
10/10 Excellent
Damon
29 Mar 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Damon
Stayed 2 nights in Mar 2025
10/10 Excellent
Shannon
19 Dec 2024
Liked: Cleanliness, staff & service, property conditions & facilities
Shannon
Stayed 1 night in Dec 2024
10/10 Excellent
Nicole
28 Mar 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Nicole
Stayed 2 nights in Mar 2025
8/10 Good
cristina
16 Aug 2024
Liked: Cleanliness, staff & service, property conditions & facilities
cristina
Stayed 1 night in Aug 2024
10/10 Excellent
Ryan
10 Jan 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Ryan
Stayed 1 night in Jan 2025
10/10 Excellent
Jennifer
9 Mar 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Jennifer
Stayed 2 nights in Mar 2025
8/10 Good
Tracy
8 Jul 2025
Liked: Cleanliness, amenities, property conditions & facilities
Tracy
Stayed 3 nights in Jul 2025
10/10 Excellent
Anthony
30 Mar 2025
Liked: Amenities
Anthony
Stayed 1 night in Mar 2025
8/10 Good
Kim
1 Jan 2025
Liked: Cleanliness, property conditions & facilities, room comfort
Kim
Stayed 1 night in Dec 2024
10/10 Excellent
Kimberly
11 Feb 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Kimberly
Stayed 4 nights in Nov 2024