A space shuttle exhibit with a large model of a space shuttle, a red pillar, and informational displays.

St. Louis Hotel Guide - St. Louis Science Center hotels in St. Louis, United States of America.

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
17 Jul - 19 Jul
Next weekend
24 Jul - 26 Jul

Filter by

Guest rating
Guest rating
Star rating

Our top choices for St. Louis Science Center hotels

Indoor pool

Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 1 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Clean rooms, comfortable beds, friendly staff."
United States
Krystina
The price is €143
includes taxes & fees
2 Aug - 3 Aug
Hampton Inn & Suites St. Louis at Forest Park
Lobby

Drury Inn & Suites St. Louis Forest Park

Drury Inn & Suites St. Louis Forest Park
3.0 star property
2 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,002 reviews)
"Clean rooms, Breakfast was great. Adjoining restaurant was convenient and delicious."
United States
Sarah
The price is €152
includes taxes & fees
23 Jul - 24 Jul
Drury Inn & Suites St. Louis Forest Park
Lobby

AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End, 1.8 km from St. Louis Science Center
9.0 out of 10, Wonderful, (786 reviews)
"Such a nice hotel!!"
United States
Elizabeth
The price is €147
includes taxes & fees
2 Aug - 3 Aug
AC Hotel St. Louis Central West End
Courtyard

Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown
3.0 star property
Midtown, 2.7 km from St. Louis Science Center
9.0 out of 10, Wonderful, (780 reviews)
"Really enjoyed my stay I will return"
United States
Brittany
The price is €138
includes taxes & fees
6 Aug - 7 Aug
Element by Marriott St. Louis Midtown
Bar (on property)

Aloft by Marriott St. Louis Cortex

Aloft by Marriott St. Louis Cortex
3.0 star property
Central West End, 1.8 km from St. Louis Science Center
8.6 out of 10, Excellent, (972 reviews)
"Great Stay"
United States
Larry
The price is €116
includes taxes & fees
3 Aug - 4 Aug
Aloft by Marriott St. Louis Cortex
Outdoor spa tub

The West End

The West End
2.0 star property
Central West End, 2.3 km from St. Louis Science Center
8.6 out of 10, Excellent, (580 reviews)
"This place was super cute and the staff was amazing. Would recommend and would stay here again."
United States
Heather
The price is €119
includes taxes & fees
22 Jul - 23 Jul
The West End
Restaurant

Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End, 1.7 km from St. Louis Science Center
8.6 out of 10, Excellent, (1,002 reviews)
"Friendly staff, clean, good location. Will stay again."
United States
Kristin
The price is €134
includes taxes & fees
9 Aug - 10 Aug
Hotel Indigo St Louis - Central West End by IHG
Terrace/patio

Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 0.9 km from St. Louis Science Center
8.6 out of 10, Excellent, (1,002 reviews)
"Breakfast is different from every other hotel breakfast which is refreshing. Nice accommodations."
United States
Brian
The price is €139
includes taxes & fees
9 Aug - 10 Aug
Home2 Suites by Hilton St. Louis/Forest Park
In-room safe, desk, blackout curtains, iron/ironing board

DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End, 1.3 km from St. Louis Science Center
8.2 out of 10, Very good, (1,005 reviews)
"Beautiful hotel in a convenient locations. Walking distance to great restaurants and coffee shops."
United States
Gary
The price is €134
includes taxes & fees
2 Aug - 3 Aug
DoubleTree by Hilton St. Louis Forest Park
Standard Double Room

Forest Park Hotel by MDR

Forest Park Hotel by MDR
3.0 star property
The Hill, 1.8 km from St. Louis Science Center
7.4 out of 10, Good, (1,629 reviews)
"Good place to stay"
United States
Jeremy
The price is €88
includes taxes & fees
16 Aug - 17 Aug
Forest Park Hotel by MDR
Superior Room, 1 King Bed (Smoke Free)

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
2.5 star property
The Hill, 1.8 km from St. Louis Science Center
5.8 out of 10, (1,000 reviews)
"Clean room , no bugs … nice staff, good coffee, and lots of food choices near"
United States
Mary
The price is €91
includes taxes & fees
20 Jul - 21 Jul
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
Lobby lounge

Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
6.5 km from St. Louis Science Center
9.6 out of 10, Exceptional, (1,023 reviews)
"Great place to vacation. Great staff and clean rooms."
United States
Shaleria
The price is €141
includes taxes & fees
16 Aug - 17 Aug
Drury Plaza Hotel St. Louis Brentwood
Hallway

Benton Park Inn

Benton Park Inn
3.5 star property
5.5 km from St. Louis Science Center
9.6 out of 10, Exceptional, (336 reviews)
"The host was super friendly, and the house was really cute. We loved the quiet neighborhood, and the breakfast the host prepared was great! We would absolutely stay again!"
United States
Shane
The price is €152
includes taxes & fees
28 Jul - 29 Jul
Benton Park Inn
Miscellaneous

The Lodge at Grant's Trail

The Lodge at Grant's Trail
3.5 star property
10.1 km from St. Louis Science Center
9.6 out of 10, Exceptional, (515 reviews)
"We loved the rooms, the staff - clark was great. Food for breakfast was delicious!!"
United States
John
The price is €149
includes taxes & fees
28 Jul - 29 Jul
The Lodge at Grant's Trail
Breakfast, lunch and dinner served

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 6.7 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,244 reviews)
"Perfect location, clean and comfortable beds!"
United States
Cindy
The price is €165
includes taxes & fees
3 Aug - 4 Aug
Live by Loews - St.Louis
Front of property

Grand Center Inn

Grand Center Inn
3.0 star property
3.5 km from St. Louis Science Center
9.4 out of 10, Exceptional, (104 reviews)
"Lovely room, easy check in, close to Fox, comfy bed"
United States
Leon and Janis
The price is €184
includes taxes & fees
19 Jul - 20 Jul
Grand Center Inn
Courtyard

The Knight Center at Washington University

The Knight Center at Washington University
2.5 star property
4.3 km from St. Louis Science Center
9.4 out of 10, Exceptional, (622 reviews)
"Highly recommend staying at this hotel."
United States
Carla
The price is €137
includes taxes & fees
19 Jul - 20 Jul
The Knight Center at Washington University
Terrace/patio

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
Laclede's Landing, 7.5 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,001 reviews)
"It was ok"
United States
Sasha- Kay
The price is €382
includes taxes & fees
22 Jul - 23 Jul
Four Seasons Hotel St Louis
Terrace/patio

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
5.5 km from St. Louis Science Center
9.4 out of 10, Exceptional, (895 reviews)
"Clean room, comfy bed, friendly staff, great location!! Would definitely stay here again!!"
United States
MARY
The price is €121
includes taxes & fees
9 Aug - 10 Aug
Courtyard by Marriott St. Louis Brentwood
Property amenity

Residence Inn By Marriott St. Louis Clayton

Residence Inn By Marriott St. Louis Clayton
3.0 star property
Clayton, 6.8 km from St. Louis Science Center
9.4 out of 10, Exceptional, (227 reviews)
"Our stay was very good!"
United States
Donna
The price is €173
includes taxes & fees
9 Aug - 10 Aug
Residence Inn By Marriott St. Louis Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to St. Louis Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Indoor pool
Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
9.4
Exceptional
1,002 reviews
View
Lobby
Drury Inn & Suites St. Louis Forest Park
3.0 star property
9.4
Exceptional
1,002 reviews
View
Lobby
AC Hotel St. Louis Central West End
4.0 star property
9.0
Wonderful
786 reviews
View
Courtyard
Element by Marriott St. Louis Midtown
3.0 star property
9.0
Wonderful
780 reviews
View
Bar (on property)
Aloft by Marriott St. Louis Cortex
3.0 star property
8.6
Excellent
972 reviews
View

Top St. Louis Science Center Hotel Reviews

Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park

10/10 Excellent
"Good place"
James 1-night trip
Posted 5 hours ago
Hampton Inn & Suites St. Louis at Forest Park

Hotels near other St. Louis Science Center attractions

A modern building with large glass windows and a garden with red and pink tulips.

Jewel Box

Made of stacked glass in a restored art deco style, this glass house from the 1930s continues to flourish with tropical trees, hanging plants and a large fountain.
See properties

Frequently asked questions

What's the area like around St. Louis Science Center?
St. Louis Science Center is located in a welcoming area of St. Louis known for its picturesque gardens and sporting events. If you're looking for a convenient place to stay, take a look at the 63 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near St. Louis Science Center?
Hampton Inn & Suites St. Louis at Forest Park is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.6 mi (1 km) from St. Louis Science Center. Other good choices within a short distance include DoubleTree by Hilton St. Louis Forest Park and Home2 Suites by Hilton St. Louis/Forest Park.
How many hotels should I expect to find close to St. Louis Science Center?
Expedia has 63 hotels and other accommodation options within a mile from St. Louis Science Center.
If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals near St. Louis Science Center.
What can I see and do near St. Louis Science Center?
Cathedral Basilica of St. Louis, Missouri History Museum and St. Louis Art Museum feature captivating exhibits. St. Louis Union Station, Jewel Box and Cherokee Street are monuments to see when you're exploring the area around St. Louis Science Center. You can check out the local talent at The Muny Theater, Fox Theater and Sheldon Concert Hall.