Holiday Rentals in St Mary

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Our top choices for St Mary holiday rentals

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
9.8 out of 10, Exceptional, (46)
"The cabin was cozy and very peaceful such a good experience "
United States
Russhell
The price is €118
includes taxes & fees
5 Jan - 6 Jan 2026
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Cozy 1-bedroom house with AC and WiFi in charming Farmington

Cozy 1-bedroom house with AC and WiFi in charming Farmington
Farmington
10.0 out of 10, Exceptional, (6)
"A very nice place to stay. It is close to everything we were interested in doing.Everything worked as advertised. "
United States
Cary B.
The price is €162
includes taxes & fees
29 Dec - 30 Dec
Cozy 1-bedroom house with AC and WiFi in charming Farmington

⚜️Rivertown Retreat⚜️ Lewis & Clark stayed here. King bed. Sleeps 4

⚜️Rivertown Retreat⚜️ Lewis & Clark stayed here. King bed. Sleeps 4
2.0 star property
Ste. Genevieve
10.0 out of 10, Exceptional, (18)
"Great historic property!"
United States
Rhonda R.
The price is €181
includes taxes & fees
29 Dec - 30 Dec
⚜️Rivertown Retreat⚜️ Lewis & Clark stayed here. King bed. Sleeps 4

Vallee Suite at Baetje Farms

Vallee Suite at Baetje Farms
Bloomsdale
10.0 out of 10, Exceptional, (4)
"It was beautiful, quite and everything we expected!! Thanks for a great stay!!"
United States
Heather
The price is €123
includes taxes & fees
29 Dec - 30 Dec
Vallee Suite at Baetje Farms

"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
2.0 star property
Farmington
10.0 out of 10, Exceptional, (8)
"It is a very nice place and very comfortable has everything you could possibly need for homeaway from home."
United States
Scott
The price is €204
includes taxes & fees
4 Jan - 5 Jan 2026
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

THE CAAMP. Gorgeous 2-bedroom tiny home. Very close to the Barn/Pebble Creek

THE CAAMP. Gorgeous 2-bedroom tiny home. Very close to the Barn/Pebble Creek
Ste. Genevieve
10.0 out of 10, Exceptional, (5)
"Tiny house was absolutely perfect for a quick getaway or even a longer stay had everything we needed except a toaster! Owners were great on getting in touch for anything needed."
United States
Deborah J.
The price is €225
includes taxes & fees
29 Dec - 30 Dec
THE CAAMP. Gorgeous 2-bedroom tiny home. Very close to the Barn/Pebble Creek

"Little Brick House on Main (1865)”

"Little Brick House on Main (1865)”
Ste. Genevieve
10.0 out of 10, Exceptional, (63)
"Great place to stay!"
United States
Lettitia B.
The price is €139
includes taxes & fees
29 Dec - 30 Dec
"Little Brick House on Main (1865)”

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
2.0 star property
Farmington
10.0 out of 10, Exceptional, (13)
"Great place and very comfortable! Hosts were super attentive when our door code didn’t work and got us sorted out right away. "
United States
Kyser B.
The price is €205
includes taxes & fees
29 Dec - 30 Dec
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

Cozy Three bedroom home in Central Farmington

Cozy Three bedroom home in Central Farmington
Farmington
9.6 out of 10, Exceptional, (29)
"House was adorable and comfortable. Location close to everything. Drive to The Landing was not bad at all. Host was friendly and available. I would stay again!"
United States
Jody C.
The price is €215
includes taxes & fees
29 Dec - 30 Dec
Cozy Three bedroom home in Central Farmington

Beautiful Modern Loft In Wine Country!

Beautiful Modern Loft In Wine Country!
Ste. Genevieve
10.0 out of 10, Exceptional, (271)
"It appeared to be. We never cooked anything during our stay. The host were very friendly and helpful during our stay. It is a beautiful place that is nice and relaxing. "
United States
stephanie b.
The price is €158
includes taxes & fees
30 Dec - 31 Dec
Beautiful Modern Loft In Wine Country!

Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.2 out of 10, Wonderful, (17)
"Great place to stay! "
United States
Eric
Urban Lofts

Miette Suite at Baetje Farms

Miette Suite at Baetje Farms
Bloomsdale
10.0 out of 10, Exceptional, (2)
"Beautiful space. Had a lovely time. Don’t forget to feed the goats."
United States
John P.
The price is €127
includes taxes & fees
31 Dec - 1 Jan 2026
Miette Suite at Baetje Farms

Goforth into Nature, a charming 1-bdrm home in the quiet Bloomsdale countryside.

Goforth into Nature, a charming 1-bdrm home in the quiet Bloomsdale countryside.
Bloomsdale
10.0 out of 10, Exceptional, (8)
"What a beautiful fun stay that was a nice quick getaway for us! Everything was perfect from booking, to arrival, to overall stay, we had the best time! "
United States
Blake H.
The price is €244
includes taxes & fees
30 Dec - 31 Dec
Goforth into Nature, a charming 1-bdrm home in the quiet Bloomsdale countryside.

Parkside B&B

Parkside B&B
Farmington
10.0 out of 10, Exceptional, (1)
"Great property, quiet, clean, home away from home. Thank you"
United States
ana G.
The price is €217
includes taxes & fees
28 Jan - 29 Jan 2026
Parkside B&B

Newly remodeled house minutes away from downtown, golf courses + BIG back yard

Newly remodeled house minutes away from downtown, golf courses + BIG back yard
2.0 star property
Farmington
10.0 out of 10, Exceptional, (22)
"very nice house and good location . had so many things to enjoy"
United States
Peter V.
The price is €189
includes taxes & fees
5 Jan - 6 Jan 2026
Newly remodeled house minutes away from downtown, golf courses + BIG back yard

Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Farmington
8.6 out of 10, Excellent, (4)
"Great place. "
United States
Diana
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations

Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC in lovely Weingarten.

Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC in lovely Weingarten.
New Offenburg
10.0 out of 10, Exceptional, (6)
"Relaxing setting between Farmington and St Genevieve. Both towns are rich in history and have small town charm. "
United States
Tim M.
The price is €262
includes taxes & fees
29 Dec - 30 Dec
Sunset Ridge - Peaceful 3-bedroom house with WiFi and AC in lovely Weingarten.

Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.

Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.
Ste. Genevieve
10.0 out of 10, Exceptional, (58)
"Clean spacious quiet( except for the dogs barking) kitchen pans are terrible."
United States
Barb S.
The price is €316
includes taxes & fees
1 Jan - 2 Jan 2026
Gorgeous 5 Bedroom Log Home Less Than 5 Minutes From Chaumette And Charleville.

St Francis River: The Blue Yurt and Hot Tub

St Francis River: The Blue Yurt and Hot Tub
Fredericktown
8.8 out of 10, Excellent, (18)
"Loved this rental - great property!"
United States
Julie S.
The price is €190
includes taxes & fees
28 Jan - 29 Jan 2026
St Francis River: The Blue Yurt and Hot Tub

Your home away from home in downtown, historic Farmington!

Your home away from home in downtown, historic Farmington!
Farmington
10.0 out of 10, Exceptional, (36)
"Beautiful piece of property. Would stay here again and again. "
United States
Mary N.
The price is €204
includes taxes & fees
1 Jan - 2 Jan 2026
Your home away from home in downtown, historic Farmington!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St Mary Hotel Reviews

Find out more about St Mary

Everything you need to know about St Mary holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the St Mary holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St Mary holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

St Mary holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St Mary. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A St Mary holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of St Mary holiday rentals we have selected for you start as low as €118 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on St Mary rentals

At Expedia, we put the best St Mary holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top St Mary rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St Mary holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St Mary. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

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Frequently asked questions

Can I find holiday rentals in St Mary?

Yes, there are holiday rentals close to the most popular sights in St Mary, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best holiday rentals that St Mary has to offer?

Goforth into Nature, a charming 1-bdrm home in the quiet Bloomsdale countryside.: This holiday home rental outside of St Mary is located in a rural location, and has a patio, a garden and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. You can relax into your holiday with a selection of games and 1 hot tub.

What’s there to see and do in St Mary?

Mark Twain National Forest and Mississippi River are a couple of lovely local spots to get outside and enjoy nature. In the wider area, you’ll find Fort Kaskaskia and Popeye Museum.

What are holiday rentals like in St Mary?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in St Mary. Holiday rentals provide amenities like laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about a sanitised environment, holiday rentals can provide a sense of security away from public hotel lifts and bustling concierge desks while still allowing you a great travel experience. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is an attractive choice for a family getaway.