Western Pennsylvania Guest Houses

A city skyline at night with illuminated buildings and a river reflecting the lights.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Next weekend

In two weeks

In one month

In two months

Our top choices for Western Pennsylvania guest houses

Three stained glass windows with a landscape scene.

1. Thistledown At Seger House

Ligonier

William

includes taxes & fees

19 Oct - 20 Oct

A patio with outdoor seating and a pool.

2. The Jacqueline House of Wilmington

New Wilmington

Toni

includes taxes & fees

18 Oct - 19 Oct

A spacious bedroom with a large bed, a wooden chest, a round coffee table, and a fireplace.

3. Deer Creek Winery at Watson Estate

Uniontown

Lynn

includes taxes & fees

19 Oct - 20 Oct

A lakeside cabin with a balcony, surrounded by trees and a calm water body.

4. Applebutter Inn

Slippery Rock

"Applebutter Inn is a breath of fresh air! The historic and cozy building is a welcome change from chain hotels. Julie is so kind and hospitable, we felt like old friends by the time we left. We were all charmed by her companion, Chiquita Banana, who is the sweetest pup you'll ever meet! Our room was immaculate and comfortable. We hope to make it back to Slippery Rock some day, and will definitely stay at Applebutter Inn again!"

Ellen

includes taxes & fees

25 Oct - 26 Oct

A spacious living area with a large sofa, a red armchair, and a coffee table. A kitchen with dark cabinets and a central island is visible in the background.

5. Crystal Run Suites of Springboro

Springboro

Anonymous traveller

includes taxes & fees

18 Oct - 19 Oct

A compact living space with a kitchenette, a dining area, and two checkered armchairs.

6. Peggy's Guest Hideaway

Connellsville

Kurt H.

includes taxes & fees

19 Oct - 20 Oct

A covered outdoor area with a garden, columns, and a building in the background.

7. Modern Homestead Guest House

Reedsville

dulce

includes taxes & fees

18 Oct - 19 Oct

A kitchen with dark cabinets, a white stove, and a dining table with a pumpkin decoration.

8. Cozy Country Retreat Near SPIRE, Wineries & Ashtabula Harbor. Fisherman welcome

Kingsville

Matthew

includes taxes & fees

19 Oct - 20 Oct

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Western Pennsylvania Hotel Reviews

Pittsburgh Marriott City Center

10/10 Excellent

"The location was perfect as we arrived by car and it’s close to the highway. But we could also walk to downtown theater district. The room was not only spacious but enormous. The staff were fantastic. Dee at the front desk was particularly helpful and made us feel welcome. She went above and beyond. Brian, the concierge loaned us his personal umbrella when we had to go out in the rain. My only caveat is that the on-site restaurant is not good. The service was terrible and the food was even worse. But the ambience is good. I would highly recommend this property."

TRYP by Wyndham Pittsburgh/Lawrenceville

10/10 Excellent

"This hotel is super cool! As a retired teacher, it is awesome to see an old school building turned into a nice hotel! And the bar top is a great city. I’ve stayed here a couple of times now with my daughter attending the University of Pittsburgh. It’s a great location. And the last time I was in town, I had an issue with a different reservation Trypp was able to accommodate me and my dog Max for the night! I will definitely continue to stay here when I travel to Pittsburgh to visit my daughter!"

Find out more about Western Pennsylvania