American Airlines Cheap Flights from Detroit to San Diego

View €113 flight on Wed, 8 Oct 2025Opens in a new window

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Prices were available within the past 7 days and start at €113 for one-way flights and €246 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, 8 Oct - Sun, 12 Oct
DTW
Detroit
SAN
San Diego
€246 Return, found 4 days ago
€246
Return
found 4 days ago
Select American Airlines flight, departing Wed, 8 Oct from Detroit to San Diego, returning Sun, 12 Oct, priced at €246 found 4 days ago
American Airlines
Wed, 8 Oct - Sun, 12 Oct
DTW
Detroit
SAN
San Diego
€251 Return, found 4 days ago
€251
Return
found 4 days ago
Select American Airlines flight, departing Wed, 8 Oct from Detroit to San Diego, returning Sun, 12 Oct, priced at €251 found 4 days ago
American Airlines
Wed, 8 Oct - Sun, 12 Oct
DTW
Detroit
SAN
San Diego
€295 Return, found 4 days ago
€295
Return
found 4 days ago
Select American Airlines flight, departing Wed, 8 Oct from Detroit to San Diego, returning Sun, 12 Oct, priced at €295 found 4 days ago
American Airlines
Wed, 8 Oct - Sun, 12 Oct
DTW
Detroit
SAN
San Diego
€300 Return, found 4 days ago
€300
Return
found 4 days ago
Select American Airlines flight, departing Wed, 8 Oct from Detroit to San Diego, returning Sun, 12 Oct, priced at €300 found 4 days ago
American Airlines
Wed, 8 Oct - Sun, 12 Oct
DTW
Detroit
CLD
Carlsbad
€307 Return, found 4 days ago
€307
Return
found 4 days ago
Select American Airlines flight, departing Wed, 8 Oct from Detroit to Carlsbad, returning Sun, 12 Oct, priced at €307 found 4 days ago
American Airlines
Wed, 8 Oct - Sun, 12 Oct
DTW
Detroit
SAN
San Diego
€307 Return, found 4 days ago
€307
Return
found 4 days ago
Select American Airlines flight, departing Wed, 8 Oct from Detroit to San Diego, returning Sun, 12 Oct, priced at €307 found 4 days ago
Detroit to San Diego route information
Origin airport
Detroit Metropolitan Wayne County
Destination airport
San Diego Intl.
Distance
3124 km
*Available to Expedia members.