American Airlines Cheap Flights from Houston to San Diego

View €184 flight on Thu, 5 Mar 2026Opens in a new window
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Prices were available within the past 7 days and start at €184 for one-way flights and €367 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, 5 Mar - Wed, 11 Mar
HOU
Houston
SAN
San Diego
€367 Return, found 3 days ago
€367
Return
found 3 days ago
Select American Airlines flight, departing Thu, 5 Mar from Houston to San Diego, returning Wed, 11 Mar, priced at €367 found 3 days ago
American Airlines
Thu, 5 Mar - Wed, 11 Mar
HOU
Houston
SAN
San Diego
€368 Return, found 3 days ago
€368
Return
found 3 days ago
Select American Airlines flight, departing Thu, 5 Mar from Houston to San Diego, returning Wed, 11 Mar, priced at €368 found 3 days ago
American Airlines
Thu, 5 Mar - Wed, 11 Mar
HOU
Houston
SAN
San Diego
€376 Return, found 3 days ago
€376
Return
found 3 days ago
Select American Airlines flight, departing Thu, 5 Mar from Houston to San Diego, returning Wed, 11 Mar, priced at €376 found 3 days ago
American Airlines
Thu, 5 Mar - Wed, 11 Mar
HOU
Houston
SAN
San Diego
€510 Return, found 3 days ago
€510
Return
found 3 days ago
Select American Airlines flight, departing Thu, 5 Mar from Houston to San Diego, returning Wed, 11 Mar, priced at €510 found 3 days ago

Find the cheapest month to fly from Houston (HOU) to San Diego (SAN)

February is typically the cheapest month to fly

From €80 - €329 per traveller.
Houston to San Diego route information
Origin airport
William P. Hobby
Destination airport
San Diego Intl.
Distance
2096 km
Average flight time
2 hours 55 mins

Frequently asked questions

How much is an American Airlines flight from William P. Hobby Airport (HOU) to San Diego Intl. Airport (SAN)?
Scoring cheap one-way American Airlines flights from HOU to SAN from €184 on Expedia couldn't be simpler — just filter by "Price (lowest to highest)." Or check out our budget-friendly round-trip fares from €367 for your next exciting getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly from HOU to SAN with American Airlines?
January is one of the most affordable months to jet away to San Diego with American Airlines. You could also find fantastic deals on return and one-way tickets in November.
Does American Airlines fly nonstop from William P. Hobby Airport (HOU) to San Diego Intl. Airport (SAN)?
Use our "Nonstop" filter when looking for direct American Airlines flights from HOU to SAN. You'll also be able to compare other airlines offering the same direct trip.
What airports does American Airlines fly into in San Diego?
San Diego Intl. Airport (SAN) is the main San Diego hub for American Airlines flights from William P. Hobby Airport (HOU).
Can I change or cancel my American Airlines flight from William P. Hobby Airport (HOU) to San Diego Intl. Airport (SAN)?
Changes are generally free within 24 hours of making a booking, but your airline may add a charge after that. For further details about altering your reservation, check out your "Trips," select your flight and click on "Manage Booking." If you'd like the flexibility to adjust your plans without additional charges, tick the "No cancel fee" or "Changes included" filter when organising your next break.
*Available to Expedia members.