Cheap Flights from Guatemala City to Palo Alto

View €219 flight on Fri, 22 Aug 2025Opens in a new window

Popular airlines from Guatemala City to Palo Alto

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 15% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap flights from Guatemala City to Palo Alto (GUA-SJC)

Prices were available within the past 7 days and start at €219 for one-way flights and €378 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
Fri, 22 Aug - Tue, 26 Aug
GUA
Guatemala City
SFO
San Francisco
€378 Return, found 21 hours ago
€378
Return
found 21 hours ago
Select United flight, departing Fri, 22 Aug from Guatemala City to San Francisco, returning Tue, 26 Aug, priced at €378 found 21 hours ago
United
Fri, 22 Aug - Tue, 26 Aug
GUA
Guatemala City
SFO
San Francisco
€427 Return, found 21 hours ago
€427
Return
found 21 hours ago
Select United flight, departing Fri, 22 Aug from Guatemala City to San Francisco, returning Tue, 26 Aug, priced at €427 found 21 hours ago
American Airlines
Fri, 22 Aug - Tue, 26 Aug
GUA
Guatemala City
SFO
San Francisco
€447 Return, found 21 hours ago
€447
Return
found 21 hours ago
Select American Airlines flight, departing Fri, 22 Aug from Guatemala City to San Francisco, returning Tue, 26 Aug, priced at €447 found 21 hours ago
Copa
Fri, 22 Aug - Tue, 26 Aug
GUA
Guatemala City
SFO
San Francisco
€489 Return, found 21 hours ago
€489
Return
found 21 hours ago
Select Copa flight, departing Fri, 22 Aug from Guatemala City to San Francisco, returning Tue, 26 Aug, priced at €489 found 21 hours ago
Alaska Airlines
Fri, 22 Aug - Tue, 26 Aug
GUA
Guatemala City
SFO
San Francisco
€559 Return, found 21 hours ago
€559
Return
found 21 hours ago
Select Alaska Airlines flight, departing Fri, 22 Aug from Guatemala City to San Francisco, returning Tue, 26 Aug, priced at €559 found 21 hours ago
JetBlue Airways
Fri, 22 Aug - Tue, 26 Aug
GUA
Guatemala City
SFO
San Francisco
€564 Return, found 21 hours ago
€564
Return
found 21 hours ago
Select JetBlue Airways flight, departing Fri, 22 Aug from Guatemala City to San Francisco, returning Tue, 26 Aug, priced at €564 found 21 hours ago

Find the cheapest month to fly from Guatemala City (GUA) to San Francisco (SFO)

September is typically the cheapest month to fly

From €250 - €419 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.